Amid Record Sales, SUV’s Take Center Stage at Chicago Auto Show

High gas prices and poor fuel economy led to the decline of sport utility vehicle sales in the United States in the mid-2000s, a time when customers preferred smaller, more affordable cars, some with new electric motor technology. But now, SUV’s have made a comeback, as VOA’s Kane Farabaugh reports on the floor of the Nation’s Largest Auto Show in Chicago.

First Blood Test to Help Diagnose Brain Injuries Gets US OK

The first blood test to help doctors diagnose traumatic brain injuries has won U.S. government approval.

The move means Banyan Biomarkers can commercialize its test, giving the company an early lead in the biotech industry’s race to find a way to diagnose concussions.

The test doesn’t detect concussions and the approval won’t immediately change how patients with suspected concussions or other brain trauma are treated. But Wednesday’s green light by the Food and Drug Administration “is a big deal because then it opens the door and accelerates technology,” said Michael McCrea, a brain injury expert at Medical College of Wisconsin.

The test detects two proteins present in brain cells that can leak into the bloodstream following a blow to the head. Banyan’s research shows the test can detect them up within 12 hours of injury. It’s designed to help doctors quickly determine which patients with suspected concussions may have brain bleeding or other brain injury.

Patients with a positive test would need a CT scan to confirm the results and determine if surgery or other treatment is needed. The test will first be used in emergency rooms, possibly as soon as later this year, but Banyan’s hope is that it will eventually be used on battlefields and football fields.

FDA Commissioner Dr. Scott Gottlieb said the test fits with the agency’s goals for delivering new technologies to patients and reducing unnecessary radiation exposure.

The test “sets the stage for a more modernized standard of care for testing of suspected cases,” Gottlieb said in a statement.

Traumatic brain injuries affect an estimated 10 million people globally each year; at least 2 million of them are treated in U.S. emergency rooms. They often get CT scans to detect bleeding or other abnormalities. The scans expose patients to radiation, but in many patients with mild brain injuries including concussions, abnormalities don’t show up on these imaging tests.

With Department of Defense funding, Banyan’s research shows its Brain Trauma Indicator can accurately pick up brain trauma later found on CT scans. It also shows that absence of the two proteins in the test is a good indication that CT scans will be normal. That means patients with negative blood tests can avoid CT scans and unnecessary radiation exposure, said Dr. Jeffrey Bazarian, a University of Rochester emergency medicine professor involved in Banyan’s research.

Bazarian called the test “a huge step” toward devising a blood test that can detect brain injuries including concussions.

Dr. Walter Koroshetz, director of the National Institute of Neurological Disorders and Stroke, and other brain injury experts say the test isn’t sensitive enough to rule out concussions.

“This may be a beginning. It’s not the pot of gold at the end of the rainbow,” Koroshetz said.

That prize would be a test that could detect and guide treatment for concussions and traumatic brain injuries, similar to a blood test that hospitals commonly use to evaluate suspected heart attacks, Koroshetz said.

“That’s what we’d like to have for the brain,” he said.

San Diego-based Banyan has partnered with French firm bioMerieux SA to market the test to hospitals using that company’s’ blood analyzing machines.

Other companies are developing similar blood tests to detect brain injuries. Abbott has licensed both protein biomarkers from Banyan and is developing its own blood tests. BioDirection is developing a test involving one of the proteins in Banyan’s test plus another one and using a portable device that can yield results from a single drop of blood in less than two minutes.

Quanterix is also working to develop a blood test to diagnose concussions and other brain injuries. It has licensed the use of both proteins in Banyan’s test to be used with its own technology.

Flu-stricken Texas Teacher’s Death Puts Focus on Antivirals

A Texas elementary school teacher who died almost a week after getting sick from the flu became a talking point online after her husband said she didn’t immediately fill her prescription for an antiviral drug after deeming the $116 insurance co-pay too high.

While her husband told the Wall Street Journal that he picked up the prescription the day after she refused it and she then started taking the medication, Heather Holland, 38, died three days later on Feb. 4. 

Doctors told The Associated Press that while it’s ideal to start taking antiviral medication as quickly as possible, it’s no guarantee that one’s condition will not drastically worsen.

Antivirals make it “not zero, but less likely” that complications will develop, said Dr. William Schaffner, infectious diseases specialist at the Vanderbilt University Medical Center in Nashville, Tennessee, who added, “antivirals are not a magic potion.”

Frank Holland of Willow Park, just west of Fort Worth, told the newspaper that his wife, a second-grade teacher, came home feeling a bit sick Jan. 29. The mother of two went to work in nearby Weatherford on Jan. 30 but by evening had a fever. 

She went to the doctor on Jan. 31. Frank Holland said a rapid flu test was positive for influenza B. The doctor wrote her a prescription for oseltamivir phosphate, a generic form of the antiviral medication Tamiflu.

Frank Holland told the Wall Street Journal that they had the money, but she was frugal and didn’t want to fill it. 

She went to a Fort Worth hospital on Feb. 2. The following day, blood tests showed she had sepsis, a complication of infections, he said.

Antiviral drugs – when taken within 48 hours after becoming sick – can lessen symptoms, shorten the time one is sick by about one day and reduce complications. 

“There are people who are going to do very well, regardless of getting Tamiflu or not. There are people that are going to do very poorly, regardless of getting Tamiflu or not. And then there’s kind of the middle segment of the population where Tamiflu really may push them to the right outcome,” said Dr. Luis Ostrosky, an infectious disease expert with McGovern Medical School at UTHealth and Memorial Hermann-Texas Medical Center in Houston.

Dr. Trish Perl, chief of infectious diseases at UT Southwestern Medical Center in Dallas, said that “in some cases it may be useful” to give patients an antiviral even after the 48-hour onset. 

The Centers for Disease Control and Prevention said the flu shot is the best way to prevent seasonal flu. Frank Holland said he couldn’t remember whether she got a flu shot this season. Generally, he said, they’ve both been “pretty healthy.”

Study: Partial Dose of Yellow Fever Vaccine Provides Protection

When stockpiles of yellow fever vaccine run low, partial doses are effective, according to a new study.

The report on the vaccine, which currently is in short supply, comes as officials in Brazil attempt to contain an outbreak with what they describe as the largest-ever mass vaccination campaign using partial doses.

Yellow fever is a mosquito-borne viral disease found in tropical Africa and South and Central America. Severe cases can cause jaundice and death, but most cases involve fever, muscle pain and vomiting.

Congo outbreak, experiment

During a major outbreak in the Democratic Republic of the Congo in 2016, the government aimed to prevent the disease from spreading in the capital, Kinshasa. Health officials launched a mass vaccination campaign targeting 7.6 million people.

But the outbreak had depleted vaccine stockpiles. Hoping to stretch the available supply, the World Health Organization reviewed the small number of available studies on using reduced doses and recommended using one-fifth of a dose per person.

It seemed to work.

Researchers took blood samples from more than 700 people before and after they received the partial dose. In the new study, published in the New England Journal of Medicine, nearly all of those vaccinated with the lower dose developed enough antibodies to the virus to prevent infection.

“That was the encouraging thing, that this can be done as a potential way — when there’s supply limitations on the vaccine — to help potentially control an outbreak,” said study co-author Erin Staples at the U.S. Centers for Disease Control and Prevention.

Hundreds infected

More than 350 people have become infected with yellow fever in Brazil since late last year, and health officials have launched a campaign targeting nearly 24 million people with a one-fifth dose of the vaccine.

Staples says the new study is good news for controlling outbreaks like Brazil’s in the short term. But, she notes, “We still need some information about how long immunity will last.”

A full dose of yellow fever vaccine provides lifelong immunity. Researchers will continue to study how long people who received partial doses are protected.

Uber’s Net Loss Widens to $4.5B for Tumultuous 2017

Ride-hailing giant Uber’s full-year net loss widened to $4.5 billion in 2017 as the company endured a tumultuous year that included multiple scandals, a lawsuit alleging the theft of trade secrets and the replacement of its CEO.

The results also showed that Uber cut its fourth-quarter net loss by 25 percent from the third quarter as new CEO Dara Khosrowshahi moves to make the company profitable ahead of a planned initial public stock offering sometime next year.

The full-year loss grew from $2.8 billion in 2016, a year with results skewed by a gain from the sale of Uber’s unprofitable business in China. Uber also said its U.S. ride-hailing market share fell from 82 percent at the start of last year to 70 percent in the fourth quarter. Uber said the share has now stabilized.

Gross revenue for the year rose 85 percent over 2016, to $37 billion.

For the fourth quarter, Uber’s net loss was $1.1 billion, down from $1.46 billion it lost in the third quarter. Bookings from fares rose 14 percent to just over $11 billion for the quarter.

While the losses are significant, the results still are positive for Uber with revenue rising and losses falling in three of four quarters in 2017, said Rohit Kulkarni, managing director of SharesPost, a research group focused on privately held companies.

The numbers show that Uber under Khosrowshahi is on a path toward profitability and a sustainable economic model, Kulkarni said. “If you draw that out further, a year from now, this could be a significant IPO waiting to happen,” he said.

Uber considers adjusted earnings before taxes as a better indicator of its financial performance rather than net earnings based on Generally Accepted Accounting Principles, which include losses for accounting purposes. On an adjusted basis, excluding stock-based compensation, legal costs, taxes and depreciation, the company lost $2.2 billion for the full year. The fourth-quarter adjusted loss was $475 million, down from $606 million to in the third quarter.

San Francisco-based Uber Technologies Inc.’s results are difficult to report because only pieces are released. Khosrowshahi detailed them on a conference call with investors Tuesday, and the company made some results public by giving them to a website called The Information.

A person briefed on the results provided some numbers and confirmed the accuracy of The Information’s story to The Associated Press on Wednesday. The person didn’t want to be identified because Uber remains a private company.

Last year was a particularly bad one for Uber with its reputation tarnished by the company’s acknowledgement of rampant sexual harassment within its ranks, a yearlong cover-up of a major computer break-in, and the use of duplicitous software to thwart government regulators.

CEO Travis Kalanick was ousted in June and replaced by Khosrowshahi in August.

Earlier this month Uber ended the autonomous vehicle trade secrets lawsuit filed by Alphabet Inc.’s Waymo for a payment of Uber stock valued by Waymo at $245 million.

How Best to Treat Opioids’ Youngest Sufferers? No One knows

Two babies, born 15 months apart to the same young woman overcoming opioid addiction. Two very different treatments.

 

Sarah Sherbert’s first child was whisked away to a hospital special-care nursery for two weeks of treatment for withdrawal from doctor-prescribed methadone that her mother continued to use during her pregnancy. Nurses hesitated to let Sherbert hold the girl and hovered nervously when she visited to breast-feed.

 

Born just 15 months later and 30 miles away at a different South Carolina hospital, Sherbert’s second child was started on medicine even before he showed any withdrawal symptoms and she was allowed to keep him in her room to encourage breast-feeding and bonding. His hospital stay was just a week.

 

“It was like night and day,” Sherbert said.

 

The different approaches highlight a sobering fact: The surge has outpaced the science, and no one knows the best way to treat the opioid epidemic’s youngest patients.

 

Trying to cope with the rising numbers of affected infants, hospitals around the United States are taking a scattershot approach to treating the tremors, hard-to-soothe crying, diarrhea and other hallmark symptoms of newborn abstinence syndrome.

 

“It’s a national problem,” said Dr. Lori Devlin, a University of Louisville newborn specialist. “There’s no gold-standard treatment.”

 

With help from $1 million in National Institutes of Health funding, researchers are seeking to change that by identifying the practices that could lead to a national standard for evidence-based treatment. A rigorous multi-center study comparing treatments and outcomes in hard-hit areas could start by the end of this year, said Dr. Matthew Gillman, who is helping lead the effort.

 

“When there’s so much variability in practice, not everyone can be doing the very best thing,” Gillman said.

 

Once the umbilical cord is cut, babies born to opioid users are at risk for developing withdrawal symptoms. By some estimates, one infant is born with the condition in the U.S. every 25 minutes. The numbers have tripled since 2008 at a rate that has solid medical research comparing treatments and outcomes struggling to keep pace.

 

Not all opioid-exposed babies develop the syndrome, but drug use late in a pregnancy increases the chances and can cause dependence in fetuses and newborns. These infants are not born with addiction, which experts consider a disease involving compulsive, harmful drug-seeking behavior. But the sudden withdrawal of opioids from their mothers may cause increased production of neurotransmitters, which can disrupt the nervous system and overstimulate bodily functions. Symptoms can last for months.

 

The condition can result from a mother’s use of illicit drugs, but it also can stem from mothers being prescribed methadone or other anti-addiction medicine. Doctors believe the benefits of that treatment for the mothers outweigh any risks to their infants.

 

The Centers for Disease Control and Prevention doesn’t routinely track the condition, but the agency’s most recent data — from 2014 — indicates that the syndrome affects nearly 11 in every 1,000 U.S. births. The CDC said it is working with the March of Dimes and several states to get a better picture of the number of affected infants and how they fare developmentally and academically into childhood.

 

Some studies have suggested possible increased risks for developmental delays and behavior problems, but no research has been able to determine if that’s due to mothers’ drug use during pregnancy, infants’ treatment after birth or something completely unrelated. And there’s no definitive evidence that these children fare worse than unexposed youngsters.

 

“It’s very, very frustrating” not knowing those answers, Devlin said. “It’s such a difficult population to go back and do research on. They’re people who often don’t trust the system, often people who have had lots of trauma in their lives.”

 

Treatment aims to reduce or even prevent symptoms. Some hospitals use morphine drops, while others use methadone and sometimes sedatives. Some send the babies straight to newborn intensive care units and some focus on comfort care from moms, allowing them to room-in with their infants. A recently published Dartmouth-Hitchcock Medical Center analysis linked rooming-in with less medication use and shorter hospital stays for infants, but it can be difficult if mothers are still in the throes of addiction.

 

A Florida hospital is even testing tiny acupuncture needles on affected infants.

 

Many hospitals use a 40-year-old scoring system to measure 21 symptoms and frame diagnosis and treatment length, but some have created their own scales.

 

The Government Accountability Office’s health care team has called for federal action to address the issue, saying the current recommendations from the U.S. Health and Human Services Department amount to a half-baked strategy lacking priorities and a timeline for implementation.

 

The department’s recommendations include education for doctors and nurses to teach them how to manage affected infants, along with an emphasis on non-drug treatment.

 

Katherine Iritani, director of the GAO’s health care team, said government officials have since indicated that they are convening experts to develop and finalize a plan by March 15.

 

“We’ll review it and make sure it’s responsive to our recommendations,” she said.

 

A separate GAO report released last week recommended beefed-up government guidance to help states implement programs that ensure safe care for opioid-affected infants and treatment for parents still struggling with drug use.

 

Medicaid pays for more than 80 percent of costs for treating affected babies, totaling about $1 billion in 2012, the GAO has found.

 

At Greenville Memorial Hospital, where Sarah Sherbert’s son was delivered two years ago, babies born to methadone users are given that drug before symptoms start and are sent home with a supply to continue treatment.

 

Clemson University research has showed that approach could reduce hospital stays by nearly half, to an average of eight days costing $11,000 compared with the state average of 15 days at a cost of $45,000.

 

“The baby has already been exposed to methadone for nine months so adding four to five weeks and making weaning gentle instead of quitting cold turkey we think won’t have any additional effect on babies’ brain development,” said Dr. Jennifer Hudson, who developed the treatment approach.

 

Sherbert, 31, said her drug use began eight years ago after she was prescribed opioid painkillers for injuries from a car accident. She was on methadone prescribed by her doctor when her daughter, now 3, was born.

 

She later lost custody after relapsing and her parents are caring for the children. Sherbert said she has been sober for a year and recently was promoted to supervisor at her job. She said she’s determined to get them back.

 

“I’ve worked so hard and come such a long way,” she said. “Seeing their little faces — that’s worth every bit of it.”

 

 

 

Fries, Not Flowers: Fast-Food Chains Try to Lure Valentines

Is that love in the air or french fries? White Castle, KFC and other fast-food restaurants are trying to lure sweethearts for Valentine’s Day.

It’s an attempt to capture a bit of the $3.7 billion that the National Retail Federation expects Americans to spend on a night out for the holiday. Restaurant analyst John Gordon at Pacific Management Consulting Group says it appeals to people who don’t want to splurge on a pricier restaurant. And some customers enjoy it ironically.

White Castle, which has been offering Valentine’s Day reservations for nearly 30 years, expects to surpass the 28,000 people it served last year. Diners at the chain known for its sliders get tableside service and can sip on its limited chocolate and strawberry smoothie. KFC is handing out scratch-and-sniff Valentine’s Day cards that give off a fried chicken aroma to diners who buy its $10 Chicken Share meals or a bucket full of Popcorn Nuggets.

Panera Bread wants couples to get engaged at its cafes; those who do can win food for their weddings from the soup and bread chain. And Wingstop sold out of its $25 Valentine’s Day kit, which came with a gift card and a heart-shaped box to fill with chicken wings. The company says 1,000 of the kits were gone in 72 hours.

US Inflation Increases Most in a Year

The U.S. on Wednesday reported its biggest increase in consumer prices in a year, pushing stocks lower in early trading.

The consumer price index, which follows the costs of household goods and services, advanced by a half percentage point in January, up from two-tenths of a point in December.

The January increase pushed the year-over-year inflation rate up by 2.1 percent. It was the same 12-month rate recorded in December, increasing fears among investors that firming inflation, along with increasing wages paid to American workers, could lead policymakers at the country’s central bank, the Federal Reserve, to boost interest rates at a faster pace.

The Labor Department said consumer prices, minus the volatile changes in food and energy costs, rose three-tenths of a percentage point in January, the largest increase since January 2017. Analysts had been expecting an increase of 0.2 percent.

Stock indexes were lower at the start of Wednesday, with the key Dow Jones industrial average falling about a third of a percentage point after a string of recent days with massive swings between losses and gains.

‘Can You Dig It?’ Africa Reality Show Draws Youth to Farming

As a student, Leah Wangari imagined a glamorous life as a globe-trotting flight attendant, not toiling in dirt and manure.

 

Born and raised in Kenya’s skyscraper-filled capital, Nairobi, the 28-year-old said farming had been the last thing on her mind. The decision to drop agriculture classes haunted her later, when her efforts in agribusiness investing while running a fashion venture failed.

 

Clueless, she made her way to an unusual new reality TV show, the first of its kind in Africa. “Don’t Lose the Plot,” backed by the U.S. government, trains contestants from Kenya and neighboring Tanzania and gives them plots to cultivate, with a $10,000 prize for the most productive. The goal: Prove to young people that agriculture can be fun and profitable.

 

“Being in reality TV was like the best feeling ever, like a dream come true for me,” Wangari said. But she found it exhausting. As callouses built up on her hands, her friends made bets that she wouldn’t succeed.

 

“Don’t Lose the Plot” is aimed at inspiring youth in East Africa to pursue agribusiness entrepreneurship. Producers said the show wants to demystify the barriers to starting a small business and challenge the prejudices against farming-related careers, even as many youths flee rural areas for urban ones.

“What we hope to achieve … is first to show people that you can make money out of farming, to change the age profile of farmers in Africa from 60 to the youth. And the next thing we want to do is to show farmers, young farmers, that they can use their mobile and technology in order to farm and achieve their goals,” producer Patricia Gichinga said. The show also offers training via online platforms and text message.

 

Attracting people to agriculture is no small challenge in Africa, where a booming young population is often put off by the image of punishing work and poor, weather-beaten farmers.

 

“Most young Africans think of farming as back-breaking labor that pays peanuts,” former Nigerian President Olusegun Obasanjo, the committee chair for the $100,000 annual Africa Food Prize and a farmer himself, wrote in the New African magazine last year. “This view, though largely inaccurate, is to some extent understandable.”

 

If Africa’s youth, who make up about 65 percent of the population, don’t venture into agribusiness, “then there is little chance that agriculture will have a transformative impact on the continent’s fortunes,” Obasanjo wrote.

 

Most experts agree that farming growth can boost African economies by increasing trade, creating more jobs and improving food self-sufficiency on a continent with the highest occurrence of food insecurity in the world.

 

But much of the potential remains untapped. Africa has over 60 percent of the world’s fertile but uncultivated land while importing $35 billion to $50 billion in food per year, the Alliance for the Green Revolution in Africa says . Weak or corrupt land governance is a challenge, as well as conflict.

 

Yields for major crops remain low compared to other regions of the world. Change must come by empowering the smallholder farmers who produce 80 percent of the food consumed on the continent, the organization says.

Now Wangari is one of them. After placing second in “Don’t Lose the Plot,” she became a full-time mushroom farmer.

 

In a damp structure of mud and clay on the outskirts of Nairobi, she has harvested her first crop and is preparing for her second. She had expected to make a $2,500 profit but took in $1,000 instead after mites from a nearby chicken house invaded and lowered her yield.

 

“When I see young men in the village now sitting idle I feel disappointed because there is a lot of idle land and they can use it to make ends meet,” she said. “They don’t require a lot of capital but they don’t have the information.”

Solar Power Push Lights Up Options for India’s Rural Women

In her village of Komalia, the fog swirls so thick at 7 a.m. that Akansha Singh can see no more than 15 meters ahead. But the 20-year-old is already cycling to her workplace, nine kilometers away.

Halfway there she stops for two hours at a computer training center, where she’s learning internet skills. Then she’s off again, and by 10 a.m. reaches the small garment manufacturing plant where she stitches women’s clothing for high-end brands on state-of-the-art electric sewing machines.

Solar energy powers most of her day — the computer training center and the 25-woman garment factory run on solar mini-grid electricity — and clean power has given her personal choice as well, she said.

If the mini-grid system had not been put in place, Singh — a recent college graduate without funds to pursue training as a teacher, the only job open to women in her village — would have had no alternative but to marry, she said.

In fact, “I would already be married off,” she told the Thomson Reuters Foundation.

Today, however, she earns 4,500 rupees ($70) a month working on solar-powered sewing machines. She uses part of that to pay 300 rupees ($4.70) a month for her computer education class — and is planning to start a computer training center closer to home.

Like her, most of the women at the factory earn between 2,500 and 4,500 rupees ($39- $70) a month, which has helped their families eat better, get children to school and pay for healthcare, they said.

“With a month’s earning alone we can buy new bicycles for ourselves and our school-going children,” Bandana Devi, a mother of four, told the Thomson Reuter Foundation, as she looked up from her sewing.

She bought one for her 12-year-old daughter, she said, and her 6-year-old rides pillion with her to the school, 2 km away.

Prime Minister Narendra Modi has announced a $2.5 billion plan to electrify every Indian household by 2019 — a huge task in a country where close to 240 million people still have no access to electrical power.

Solar power — including the use of small local grids — is likely to be a big part of the push, with 60 percent of new connections expected to be to renewable power, according to a report by the International Energy Agency.

Stable Power, More Contracts

In a clearing in an acacia plantation, the more than 140 solar panels that make up the Kamlapur mini-grid are being cleaned early in the morning.

The 36-kilowatt plant, set up by the for-profit OMC Power Private Ltd.(formerly Omnigrid Micropower Company) in 2015, distributes solar energy over 2.4 kilometers of power lines to 70 households, two telecommunications towers, the clothing manufacturing unit and several other small businesses.

Solar mini-grids usually rely on one or two large users of power — often mobile phone towers — to provide a stable base revenue for the system. But as solar electricity becomes available in areas beyond the traditional grid, power-hungry small businesses are emerging that could become anchor users.

Kamlapur’s garment factory, for instance, consumes 10 kilowatts of power each day — the same as the telecom towers, said Ketan Bhatt, an OMC official in Uttar Pradesh state.

The state in 2016 became India’s first to put in place a mini-grid policy, recognizing private solar companies as legitimate players in India’s push to get power to all.

Company owners, in turn, say solar mini-grids — which can be more reliable than the unstable grid power their competitors rely on — is giving them a business advantage.

“Because the power supply is steady, we are regularly able to deliver on contract deadlines, which in turn enhances our reputation to bag more contracts,” said Mohammad Riyaz, who set up the Kamlapur garment unit in 2016.

Rohit Chandra, a co-founder of OMC, said he was seeing many solar power users moving beyond simply buying power for home lighting and appliances. Now, he said, they are harnessing solar energy for profit.

“We see barbers installing televisions and fans in their shops to attract more customers. Carpenters buy electric saws and wood polishers, fruit sellers are adding electric juicers. Health centers and dispensaries are coming up in underserved villages too,” Chandra said in a telephone interview.

“People are now continuously climbing,” he said.

Sangeeta Singh, of the Uttar Pradesh New and Renewable Energy Development Agency, said rural villagers “are willing to pay for assured, customized hours of supply, even at a higher price.”

“The myth that rural consumers will not pay for electricity is now demolished,” added Jaideep Mukherji, the CEO of Smart Power India (SPI). “Over the last two years we’ve discovered not only do rural consumers pay for the electricity, 93 percent pay on time.”

SPI is backed by the the U.S.-based Rockefeller Foundation’s $75 million Smart Power for Rural Development initiative, which aims to get power the “last mile” to users without it in India, Myanmar and sub-Saharan Africa.

SPI works with seven private mini-grid operators, including OMC, in Uttar Pradesh, Bihar and Jharkhand — some of India’s least electrified states — to boost demand for solar mini-grid power and help develop rural economies.

The aim is both to improve life for poor people in power-hungry regions and help make sure solar mini-grid power is financially feasible for its operators, Mukherji said.

Chandra, of OMC, said that, on average, after supplying reliable power for a year, “we see around 30 micro-enterprises come up in each village.”

Though most are expansions of existing businesses, some are new ventures — such as a new water purifying plant in Kamlapur.

Sanskrit language teacher Aparna Mishra has just invested 400,000 rupees ($6,240) to set up a reverse osmosis water purifier.

Starting later this month, 100 customers — including schools, hotels and homes in the area — will begin receiving 20-liter refillable jars of water, dropped off at their doorstep, the entrepreneur said.

Mishra’s two-year target is to produce 3,000 liters of clean water a day, delivered over a 12-km radius from the 5-kilowatt plant.

“If villagers can understand the link between good health and clean drinking water from my plant, that itself is the biggest return on my investment,” the 26-year-old told the Thomson Reuters Foundation.

An assessment of Smart Power India villages at the end of 2016 found that after two years of access to mini-grid power, small businesses using it had increased their monthly income by 13 percent.

A Price Too High?

While Smart Power India is reaching a growing share of communities without electricity, a 2017 study by the International Center for Research on Women found that large numbers of women and poor families still lack access to clean energy, even in areas where it is available.

For some of them, the cost of private mini-grid power is a deterrent to using it.

Riyaz’s clothing factory, for instance, pays 25 rupees (39 cents) for each kilowatt of the 10 kilowatts of power it uses each day — well above the 11 to 17 rupees that rural users of grid power pay.

“The electricity bill pinches,” the 45-year-old tailor said.

Chandra, of OMC, admitted that “on the face of it, our charges for reliable power might look high.”

But grid power users in Uttar Pradesh must pay a minimum monthly fee of 1,000 rupees, he said. With many small solar businesses — such as phone recharging — using less power, and even larger businesses often saving energy by using efficient machines, solar mini-grid power can come out cheaper, he said.

Surgical Infections More Common in Low-Income Countries, Study Finds

Surgeries in low-income countries had higher rates of infections than those in higher-income countries, according to a new study published in The Lancet Infectious Diseases.

The authors said their report provided a starting point for making surgery safer.

Infections at the site of surgery are the most common complications after operations. These infections raise the cost of procedures that are already expensive. And they often make recovery longer and more painful.

The study looked at more than 12,000 gastrointestinal surgeries at 343 hospitals in 66 countries.

Marked difference

Overall, about one in 10 patients developed a surgical site infection. But in low-income countries, that rate rose to nearly one in four.

That’s after taking into account factors such as the patient’s health, the type of surgery and the condition being treated.

Other elements that could have been behind the difference included the kinds of facilities available in low-income countries, or how long it took to get patients to a hospital, said study co-author Ewen Harrison at the University of Edinburgh.

“If you’re in rural sub-Saharan Africa and you’re run over by a car, it may be a number of days before you can get to a hospital,” he said. “During that time, infection can get into wounds.”

Drug resistance

Another component could have been the availability of effective antibiotics, Harrison said.

Antibiotics were nearly always given before surgery to prevent infection. But overall, about one in five surgical site infections were resistant to these antibiotics. The rate was higher in low-income countries — one in three — but the authors cautioned that they did not have enough data to draw firm conclusions.

Resistance generally develops faster the more antibiotics are used. The study noted that hospitals in low-income countries gave patients more antibiotics than elsewhere, both before and after surgery.

“That may be completely appropriate if the patients are needing the antibiotics,” Harrison said. “But that may also be an area where unnecessary use of antibiotics could be reduced in order to reduce drug resistance.”

The authors’ next plan is to test different skin-cleaning techniques, antibiotic-impregnated stitches, and other simple, low-cost methods to reduce surgical site infections in low-income countries.

More than 1,500 health care providers took part in the research. Harrison said the study organizers “crowdsourced” their participants, using social media to recruit young surgeons-in-training around the world.

“They are really the driving force behind the change that we hope to happen,” he said.

US Social Media Firms Step Up Help on Security Efforts, Intelligence Leaders Say

Leaders of U.S. national security and law enforcement agencies said Tuesday the U.S. private sector has been helpful in efforts to keep the country safe.

While the leaders did not name companies, industry sectors or what specific help has been provided, they did discuss the challenges of monitoring social media.

The comments may reflect a shift in what law enforcement has seen as the technology industry’s adversarial approach when it comes to fighting crimes and addressing national security issues.

The most notable example of this tension was support by tech industry groups for Apple’s battle with law enforcement over breaking the encryption of an iPhone used by the man who killed 14 people in the 2015 terrorist attack in San Bernardino, California.

‘Forward-leaning engagement’

At a Senate Intelligence Committee hearing Tuesday, Dan Coats, director of National Intelligence, said the U.S. government has received more support from those in the private sector “who are beginning to recognize ever more the issues that are faced with the material that comes through their processes.”

Christopher Wray, director of the Federal Bureau of Investigation, referred to the help from the private sector as a “more forward-leaning engagement.”

“So, it’s teamwork within the intelligence community and then partnership with the private sector, which is, I think, the other big change I’ve noticed — is a lot more forward-leaning engagement with the private sector in terms of trying to share information and raise awareness on their end,” said Wray, also speaking at the hearing.

“Because at the end of the day, we can’t fully police social media, so we have to work with them so that they can police themselves a little bit better as well,” Wray added.

Gates: Be careful of arrogance

Separately, Bill Gates, the co-founder of Microsoft, said in an interview that tech firms need to be careful of being too arrogant when working in realms outside their businesses or they’ll face the kind of government intervention his firm experienced in its antitrust dispute.

“The tech companies have to be careful that they’re not trying to think their view is more important than the government’s view, or than the government being able to function in some key areas,” said Gates in an interview with Axios.

Gates cited Apple’s iPhone battle with the government, criticizing “their view that even a clear mass-murdering criminal’s communication should never be available to the government.”

“There’s no question of ability,” he said about unlocking the iPhone. “It’s the question of willingness.”

He also cited companies’ “enthusiasm about making financial transactions anonymous and invisible.”

Microsoft’s consent decree with the U.S. Justice Department came to an end in 2011, a result of the government’s settlement with the software giant in its antitrust case.

Remarks on Trump administration

On Tuesday, Gates and his wife, Melinda, issued their foundation’s annual letter.

In terms of the Trump administration, Gates wrote that while “we disagree with this administration more than the others we’ve met with, we believe it’s still important to work together whenever possible. We keep talking to them because if the U.S. cuts back on its investments abroad, people in other countries will die, and Americans will be worse off.”

Melinda Gates wrote that the president is a role model of “American values in the world.” She continued, “I wish our president would treat people, and especially women, with more respect when he speaks and tweets.”

US Postal Service Rolls Out Virtual Mail

A new service that sends virtual images of the day’s mail to inboxes, before snail mail arrives in actual mailboxes, is now a reality in the United States.  

“Informed Delivery” is the latest way the United States Postal Service (USPS) is trying to stay competitive.  

“Informed Delivery is a way for you to receive an email every single day of all the digital images of all your mail,” explained David Rupert, media relations specialist at USPS.  Rupert said his digital images arrive around 9 a.m. each day.

Though the USPS delivers about 46 percent of the world’s total mail, it is battling email, text messages, online advertising, television and other delivery services for consumers’ attention and business.

 

“In a digital world, more and more people are having their bills delivered online, paying them on line. And that’s starting to cut into the overall letter volume, as well as the handwritten letter and the notes that we used to send. The reality is, we’re not doing that anymore. That’s not just a U.S. trend, that’s a worldwide trend,” Rupert said.

WATCH: USPS Enters Digital, Virtual, Augmented Worlds to Attract Customers

Battling that trend also means using virtual and augmented technology in advertising, often called “junk” mail.

“What you can do is to take your cellphone, and you can take a mail piece, and it will interact with that mail piece,” Rupert described.

If there is a special digital code on an ad, consumers can scan it with their mobile device and an animated, augmented reality ad will appear.  An advertiser can also send a cardboard virtual reality headset along with a code for mobile phone users to scan.  What shows up is a VR ad that can be inserted into the headset for a 360-degree experience.

Virtual and augmented reality advertising are getting mixed results from consumers.

“Not all junk mail [pieces] are junk mail. You can find some good [things] within the junk mail. It’s a good idea. We’ll see how it works out,” said consumer Victor Teah.

 

“For some, that might be fun. But for me, I wouldn’t have any use for it,” consumer Jocelyn Coatney said.

Informed Delivery has broader appeal.

“I think I would like that a lot, especially with checks and things coming in, and things coming in from grandkids. That would be a nice service,” said Coatney.

 

Rupert added: “We don’t want to be a world leader on technology, but we certainly want to make our services relevant to you — in your home and in your neighborhood.”

Bill and Melinda Gates Talk Trump, Taxes

Bill and Melinda Gates say they’re concerned about some of President Donald Trump’s policies and statements. Here are some excerpts from their recent interview with The Associated Press:

Giving pledge

Bill Gates says he’s met with Trump twice since he took office. The Microsoft co-founder hasn’t asked Trump to sign “The Giving Pledge,” a movement Gates founded that asks billionaires to commit to donating most of their wealth to charity.

“We’ve never had a direct conversation about that,” Gates said. “It’s always a voluntary thing, and as I do dinners, I meet with a lot of people but never discussed it with him.”

Women, minorities

Melinda Gates, who left her job at Microsoft to raise their three children before turning to the foundation full-time, has lately embraced her role as a public figure more boldly. She called out Trump’s behavior, including what she described as his habit of using Twitter to attack women and minority groups.

“Those kinds of comments just don’t belong in the public discourse,” Melinda Gates said.

Tax overhaul

Bill Gates is among the billionaires who have advocated for more taxes on the wealthy. He says Trump’s tax overhaul mostly benefits corporations.

“We’ve in a broad sense said taxes should be more progressive, and this was not a move toward being more progressive.”

Feminism

Melinda Gates says some of Trump’s comments about women have troubled her, but his rejection of the “feminist” label has not.

“Some men have trouble — and some women, quite frankly — have trouble embracing that term and what it means, so that honestly doesn’t bother me. It’s more the specific comments he’s made over and over again about specific people or minorities or women that just do not reflect the values I see across the United States.”

Russian Cargo Ship Launched to ISS After 2-Day Delay

An unmanned Russian cargo ship has blasted off for the International Space Station, two days after the original launch was scrubbed.

The Progress capsule is carrying 2.7 metric tons (3 U.S. tons) of food, fuel and other supplies. It entered orbit eight minutes after liftoff Tuesday from the Russian space complex in Baikonur, Kazakhstan.

 

The abandoned Sunday launch was intended to test a new regime for fast deliveries to the space station, docking less than four hours after launch. But Tuesday’s launch will follow a longer route, with docking scheduled for Thursday.

 

There are six astronauts aboard the space station – three Americans, two Russians and one from Japan.

 

GM to Close Auto Plant in South Korea in Restructuring

General Motors said Tuesday it will close an underutilized factory in Gunsan, South Korea, by the end of May as part of a restructuring of its operations.

 

The move is a setback for the administration of President Moon Jae-in, who has made jobs and wages a priority.

 

A GM statement said Monday the company has proposed to its labor union and other stakeholders a plan involving further investments in South Korea that would help save jobs.

 

“As we are at a critical juncture of needing to make product allocation decisions, the ongoing discussions must demonstrate significant progress by the end of February, when GM will make important decisions on next steps,” Barry Engle, GM executive vice president and president of GM International, said in the statement.

 

The company’s CEO Mary Barra has said GM urgently needs better cost performance from its operations in South Korea, where auto sales have slowed.

 

South Korea’s government expressed “deep regret” over the factory’s closure. It said it plans to study the situation at the business and will continue talks with GM.

Korea’s finance ministry said earlier this month that GM had sought government help. The government has denied reports that South Korea will raise the issue in trade talks with the U.S.

 

The factory in Gunsan, a port city about 200 kilometers (125 miles) southwest of Seoul, has been making the Cruze, a sedan, and the Orlando model SUV. It employs about 2,000 workers, and only used about 20 percent of its full production capacity in 2017, rolling out 33,982 vehicles.

 

GM Korea has made 10 million vehicles since it was set up in 2002. In 2017, it sold 132,377 units in Korea and exported 392,170 vehicles to 120 markets around the world.

Opioid Makers Gave $10 Million to Advocacy Groups Amid Epidemic

Companies selling some of the most lucrative prescription painkillers funneled millions of dollars to advocacy groups that in turn promoted the medications’ use, according to a report released Monday by a U.S. senator.

The investigation by Missouri’s Senator Claire McCaskill sheds light on the opioid industry’s ability to shape public opinion and raises questions about its role in an overdose epidemic that has claimed hundreds of thousands of American lives. Representatives of some of the drugmakers named in the report said they did not set conditions on how the money was to be spent or force the groups to advocate for their painkillers.

The report from McCaskill, ranking Democrat on the Senate’s homeland security committee, examines advocacy funding by the makers of the top five opioid painkillers by worldwide sales in 2015. Financial information the companies provided to Senate staff shows they spent more than $10 million between 2012 and 2017 to support 14 advocacy groups and affiliated doctors.

The report did not include some of the largest and most politically active manufacturers of the drugs.

The findings follow a similar investigation launched in 2012 by a bipartisan pair of senators. That effort eventually was shelved and no findings were ever released.

While the new report provides only a snapshot of company activities, experts said it gives insight into how industry-funded groups fueled demand for drugs such as OxyContin and Vicodin, addictive medications that generated billions in sales despite research showing they are largely ineffective for chronic pain.

‘Pretty damning’

“It looks pretty damning when these groups were pushing the message about how wonderful opioids are and they were being heavily funded, in the millions of dollars, by the manufacturers of those drugs,” said Lewis Nelson, a Rutgers University doctor and opioid expert.

The findings could bolster hundreds of lawsuits that are aimed at holding opioid drugmakers responsible for helping fuel an epidemic blamed for the deaths of more than 340,000 Americans since 2000.

McCaskill’s staff asked drugmakers to turn over records of payments they made to groups and affiliated physicians, part of a broader investigation by the senator into the opioid crisis. The request was sent last year to five companies: Purdue Pharma; Insys Therapeutics; Janssen Pharmaceuticals, owned by Johnson & Johnson; Mylan; and Depomed.

Fourteen nonprofit groups, mostly representing pain patients and specialists, received nearly $9 million from the drugmakers, according to investigators. Doctors affiliated with those groups received another $1.6 million.

Most of the groups included in the probe took industry-friendly positions. That included issuing medical guidelines promoting opioids for chronic pain, lobbying to defeat or include exceptions to state limits on opioid prescribing, and criticizing landmark prescribing guidelines from the U.S. Centers for Disease Control and Prevention.

“Doctors and the public have no way of knowing the true source of this information and that’s why we have to take steps to provide transparency,” said McCaskill in an interview with The Associated Press. The senator plans to introduce legislation requiring increased disclosure about the financial relationships between drugmakers and certain advocacy groups.

‘Front groups’

A 2016 investigation by the AP and the Center for Public Integrity revealed how painkiller manufacturers used hundreds of lobbyists and millions in campaign contributions to fight state and federal measures aimed at stemming the tide of prescription opioids, often enlisting help from advocacy organizations.

Bob Twillman, executive director of the Academy of Integrative Pain Management, said most of the $1.3 million his group received from the five companies went to a state policy advocacy operation. But Twillman said the organization has called for non-opioid pain treatments while also asking state lawmakers for exceptions to restrictions on the length of opioid prescriptions for certain patients.

“We really don’t take direction from them about what we advocate for,” Twillman said of the industry.

The tactics highlighted in Monday’s report are at the heart of lawsuits filed by hundreds of state and local governments against the opioid industry.

The suits allege that drugmakers misled doctors and patients about the risks of opioids by enlisting “front groups” and “key opinion leaders” who oversold the drugs’ benefits and encouraged overprescribing. In the legal claims, the governments seek money and changes to how the industry operates, including an end to the use of outside groups to push their drugs.

U.S. deaths linked to opioids have quadrupled since 2000 to roughly 42,000 in 2016. Although initially driven by prescription drugs, most opioid deaths now involve illicit drugs, including heroin and fentanyl.

Companies and their contributions

Purdue Pharma, the maker of OxyContin, contributed the most to the groups, funneling $4.7 million to organizations and physicians from 2012 through last year.

In a statement, the company did not address whether it was trying to influence the positions of the groups it supported, but said it does help organizations “that are interested in helping patients receive appropriate care.” On Friday, Purdue announced it would no longer market OxyContin to doctors.

Insys Therapeutics, a company recently targeted by federal prosecutors, provided more than $3.5 million to interest groups and physicians, according to McCaskill’s report. Last year, the company’s founder was indicted for allegedly offering bribes to doctors to write prescriptions for the company’s spray-based fentanyl medication.

A company spokesman declined to comment.

Insys contributed $2.5 million last year to a U.S. Pain Foundation program to pay for pain drugs for cancer patients.

“The question was: Do we make these people suffer, or do we work with this company that has a terrible name?” said U.S. Pain founder Paul Gileno, explaining why his organization sought the money.

Depomed, Janssen and Mylan contributed $1.4 million, $650,000 and $26,000 in payments, respectively. Janssen and Mylan told the AP they acted responsibly, while calls and emails to Depomed were not returned.

US Charges 5 Ex-Venezuelan Officials in PDVSA Bribe Case

U.S. prosecutors on Monday announced charges against five former Venezuelan officials accused of soliciting bribes in exchange for helping vendors win favorable treatment from state oil company PDVSA, the latest case to stem from a $1 billion graft probe.

The indictment by the U.S. Justice Department was filed in federal court in Houston, Texas, and was made public after Spain on Friday extradited one of the former officials, Cesar Rincon, who was a general manager at PDVSA’s, procurement unit Bariven.

Others charged included Nervis Villalobos, a former Venezuelan vice minister of energy; Rafael Reiter, who worked as PDVSA’s head of security and loss prevention; and Luis Carlos de Leon, a former official at a state-run electric company.

Those three like Rincon were arrested in Spain in October at the request of U.S. authorities amid a foreign bribery investigation into the financially struggling PDVSA, or Petroleos de Venezuela SA.

De Leon, Villalobos and Reiter remain in Spanish custody.

The indictment also charged Alejandro Isturiz Chiesa, who was an assistant to Bariven’s president and remains at large.

All five face conspiracy and money laundering charges. De Leon and Villalobos were also charged with conspiring to violate the U.S. Foreign Corrupt Practices Act.

Fred Schwartz, a lawyer for Rincon, said he expected his 50-year-old client would plead not guilty when he is arraigned on March 6. Lawyers for the other defendants could not be immediately identified.

The case flowed out of a U.S. investigation into what prosecutors have previously called a $1 billion bribery plot involving payments to PDVSA officials that became public with the arrest of two businessmen in 2015.

The indictment announced on Monday said that from 2011 to 2013, the five Venezuelans sought bribes and kickbacks from vendors in exchange for helping them secure PDVSA contracts and gain priority over other vendors for outstanding invoices during its liquidity crisis.

The indictment said the five Venezuelans then used various companies and bank accounts in Switzerland, Curaçao and elsewhere to launder the money they received.

Among the vendors that they promised to help in exchange for bribes were Roberto Rincon, who was president of Tradequip Services & Marine, and Abraham Jose Shiera Bastidas, the manager of Vertix Instrumentos, the indictment said.

Both pleaded guilty in 2016 to conspiring to pay bribes to secure energy contracts. Eight other people have also pleaded guilty in connection with the U.S. investigation.

Trump: US to Push for ‘Reciprocal Tax’ on Trade Partners

U.S. President Donald Trump said on Monday he would push for a “reciprocal tax” against countries, including U.S. allies, that levy tariffs on American products, but officials did not provide details on how such a tax would be structured or what goods it would apply to.

During his populist 2016 presidential campaign, Republican Trump railed at countries that had trade surpluses “taking advantage of the United States” and he revisited the theme Monday.

“We cannot continue to let people come into our country and rob us blind and charge us tremendous tariffs and taxes and we charge them nothing,” Trump told reporters at a White House event to announce a proposed infrastructure plan.

The United States loses “vast amounts of money with China and Japan and South Korea and so many other countries … It’s a little tough for them because they’ve gotten away with murder for 25 years. But we’re going to be changing policy,” he said.

Trump said his administration will impose a “reciprocal tax” to charge other countries — “some of them are so-called allies, but they’re not allies on trade.”

Retailers and trade associations have fought a Republican proposal on how imports are taxed because they believe it hurts their businesses and would lead to higher prices for consumers on basic items such as food and clothing.

Republicans in the U.S. House of Representatives, as they began to assemble a tax reform plan last year, proposed imposing a 20 percent border-adjustment tax on imports that was designed to offset the value-added tax refunds that some countries grant to their exporters.

But the idea was dropped after it ran into stiff opposition from retailers and other industries that depend on imported materials. The National Retail Federation called it a “bad tax” that would “drive up the prices of countless products Americans use every day.”

Last April on Fox Business Network, Trump suggested that if he said the U.S. would charge a 10 percent or 20 percent border tax “everyone goes crazy, because they like free trade” and added: “But when you say ‘reciprocal tax,’ nobody can get angry … OK, you say, ‘whatever you charge, we’re charging.'”