Trash Found Littering Ocean Floor in Deepest-Ever Sub Dive

On the deepest dive ever made by a human inside a submarine, a Texas investor and explorer found something he could have found in the gutter of nearly any street in the world: trash.

Victor Vescovo, a retired naval officer, said he made the unsettling discovery as he descended nearly 6.8 miles (35,853 feet/10,928 meters) to a point in the Pacific Ocean’s Mariana Trench that is the deepest place on Earth. His dive went 52 feet (16 meters) lower than the previous deepest descent in the trench in 1960.

Vescovo found undiscovered species as he visited places no human had gone before. On one occasion he spent four hours on the floor of the trench, viewing sea life ranging from shrimp-like anthropods with long legs and antennae to translucent “sea pigs” similar to a sea cucumber.

He also saw angular metal or plastic objects, one with writing on it.

“It was very disappointing to see obvious human contamination of the deepest point in the ocean,” Vescovo said in an interview.

Plastic waste has reached epidemic proportions in the world’s oceans with an estimated 100 million tons dumped there to date, according to the United Nations. Scientists have found large amounts of micro plastic in the guts of deep-dwelling ocean mammals like whales.

Raise awareness

Vescovo hoped his discovery of trash in the Mariana Trench would raise awareness about dumping in the oceans and pressure governments to better enforce existing regulations, or put new ones in place.

“It’s not a big garbage collection pool, even though it’s treated as such,” Vescovo said of the worlds’ oceans. In the last three weeks, the expedition has made four dives in the Mariana Trench in his submarine, DSV Limiting Factor, collecting biological and rock samples.

It was the third time humans have dived to the deepest point in the ocean, known as Challenger Deep. Canadian movie maker James Cameron was the last to visit in 2012 in his submarine, reaching a depth of 35,787 feet (10,908 meters).

Prior to Cameron’s dive, the first-ever expedition to Challenger Deep was made by the U.S. Navy in 1960, reaching a depth of 10,912 meters.

Without Heart Disease, Daily Aspirin May Be Too Risky

For people without heart disease, taking a daily aspirin to prevent heart attacks and strokes may increase the risk of severe brain bleeding to the point where it outweighs any potential benefit, a research review suggests.

U.S. doctors have long advised adults who haven’t had a heart attack or stroke but are at high risk for these events to take a daily aspirin pill, an approach known as primary prevention. Even though there’s clear evidence aspirin works for this purpose, many physicians and patients have been reluctant to follow the recommendations because of the risk of rare but potentially lethal internal bleeding.

For the current study, researchers examined data from 13  clinical trials testing the effects of aspirin against a placebo or no treatment in more than 134,000 adults.

The risk of intracranial hemorrhage, or brain bleeds, was rare: taking aspirin was associated with two additional cases of this type of internal bleeding for every 1,000 people, the study found.

But the bleeding risk was still 37 percent higher for people taking aspirin than for people who didn’t take this drug.

“Intracranial hemorrhage is a special concern because it is strongly associated with a high risk of death and poorer health over a lifetime,” said study co-author Dr. Meng Lee of Chang Gung University College of Medicine in Taiwan.

“These findings suggest caution regarding using low-dose aspirin in individuals without symptomatic cardiovascular disease,” Lee said by email.

Post-cardiac event use

For people who have already had a heart attack or stroke, the benefit of low-dose aspirin to prevent another major cardiac event is well established, researchers note in JAMA Neurology. But the value of aspirin is less clear for healthier people, for whom bleeding risks may outweigh any benefit, the study team writes.

Already, guidelines on aspirin for primary prevention of heart disease in the U.S., Europe and Australia have incorporated a need to balance the potential benefits against the risk of bleeding. For elderly people, who have a greater risk of bleeding than younger adults, the risks may be too great to recommend aspirin.

For adults ages 50 to 59 considering aspirin to prevent heart attacks and strokes, for example, the U.S Preventive   Services Task Force (USPSTF) recommends the pill only for people who have at least a 10 percent risk of having a heart attack or stroke over the next decade and who don’t have a higher-than-average risk of bleeding. (The American College of Cardiology provides an online risk calculator.

One limitation

One limitation of the analysis is that the smaller clinical trials examined a variety of aspirin doses up to 100 milligrams daily. The analysis also only focused on brain bleeds, and not on other types of internal bleeding associated with aspirin.

“We have long known that aspirin can precipitate bleeding,  most commonly in the gastrointestinal tract, but most devastatingly in the brain,” said Dr. Samuel Wann, a cardiologist at Ascension Healthcare in Milwaukee, Wisconsin, who wasn’t involved in the study.

Despite the benefits for preventing heart attacks, the consensus on aspirin has changed over time, particularly for people without heart disease or hardening and narrowing of thearteries (atherosclerosis).

“We have previously recommended aspirin to prevent platelets from sticking to the inside of an individual’s arteries, but the benefit, while real, turns out to be small compared to the rare but devastating incidence of brain hemorrhage,” Wann said by email. “We no longer recommend routine use of aspirin in individuals who have no demonstrable cardiovascular disease or atherosclerosis.”

 

Trump Says US Tariffs on Chinese Goods ‘Fill US Coffers’

U.S. President Donald Trump on Monday said U.S. tariffs on China bring billions of dollars into U.S. coffers. He said China’s retaliatory tariffs can have no effect on the U.S. economy. The escalation of the U.S.-China trade war sent stock markets tumbling on Monday, with the Dow Jones Industrial Average falling more than 600 points. Earlier, China announced new tariffs of up to 25 percent on $60 billion worth of U.S. goods, starting June 1. VOA’s Zlatica Hoke has more.

Supreme Court Allows Lawsuit Over iPhone Apps

The Supreme Court is allowing consumers to pursue an antitrust lawsuit that claims Apple has unfairly monopolized the market for the sale of iPhone apps.

New Justice Brett Kavanaugh is joining the court’s four liberals Monday in rejecting a plea from Cupertino, California-based Apple to end the lawsuit over the 30 percent commission the company charges software developers whose apps are sold through the App Store.

 

The lawsuit was filed by iPhone users who must purchase software for their smartphones exclusively through Apple’s App Store.

 

Four conservative justices dissented.

 

 

China Imposes Tariffs on $60 Billion in US Exports

China said Monday it would impose tariffs on $60 billion worth of imports from the United States, retaliating after President Donald Trump boosted taxes on $200 billion worth of Chinese goods sent to the U.S. and moved to impose duties on another $300 billion of Chinese exports.

The Chinese finance ministry said its new 5% to 25% tax would be imposed June 1 and affect 5,140 U.S. products exported to China. Beijing said its response was targeting “U.S. unilateralism and trade protectionism.”

“China will never succumb to foreign pressure,” the foreign ministry said. “We are determined and capable of safeguarding our legitimate rights and interests. We still hope that the U.S. will meet us half way.”

The new Chinese taxes came hours after Trump, on Twitter, urged China not to strike back, claiming that “China has taken so advantage of the U.S. for so many years, that they are way ahead (Our Presidents did not do the job). Therefore, China should not retaliate-will only get worse!”

The escalation of the tit-for-tat tariff increases had an immediate effect on the U.S. stock market, with the key Dow Jones Industrial Average plunging more than 2% in mid-day trading in New York.

The Chinese announcement came after the world’s two biggest economies ended their latest trade talks Friday in Washington without reaching a deal.

‘Both sides will suffer’

Chief White House economic adviser Larry Kudlow told Fox News Sunday that “both sides will suffer” from the escalating trade war.

Trump claimed in another tweet, that “Their (sic) is no reason for the U.S. Consumer to pay the Tariffs, which take effect on China today.” But Kudlow acknowledged, “In fact, both sides will pay. Both sides will pay in these things.”

The U.S. leader has claimed that the Chinese government unfairly subsidizes Chinese companies and steals intellectual property from U.S. firms to manufacture its own products.

Kudlow said that in the U.S. “maybe the toughest burdens” are on farmers who sell soybeans, corn and wheat to China. But he said the Trump administration has “helped them before on lost exports” with $12 billion in past subsidies and that “we’ll do it again if we have to and if the numbers show that out.” Trump has said he will ask Congress to approve another $15 billion in farm subsidies to offset lost sales to China.

‘Right where we want to be’

Trump said on Twitter Sunday “We are right where we want to be with China.”

Trump on Friday more than doubled tariffs on $200 billion of Chinese goods, boosting the rate from 10% to 25%, while also moving to impose tariffs on an additional $300 billion of Chinese products, although Kudlow said it could take months for the full effect of the tariffs to be felt. China had previously imposed taxes on $110 billion of American products before Monday’s tariff increase.

Despite the break-off in trade talks Friday, Kudlow said, “We were moving well, constructive talks and I still think that’s the case. We’re going to continue the talks as the president suggested.”

Kudlow said Trump and Chinese President Xi Jinping are likely to discuss trade issues at the G-20 summit in Japan at the end of June.

The economic adviser renewed U.S. claims that China had backtracked from earlier agreements reached in the talks, forcing negotiators to cover “the same ground this past week.”

“You can’t forget this: This is a huge deal, the broadest scope and scale ….two countries have ever had before,” Kudlow said. “But we have to get through a lot of issues. For many years, China trade was unfair, non-reciprocal, unbalanced in many cases, unlawful.”

The U.S. has claimed that China steals technology and forces U.S. companies to divulge trade secrets it uses in its own production of advanced technology products.

On Saturday, Trump suggested that China could be waiting to see if he wins reelection next year, but said Beijing would be “much worse” off during a second term of his in the White House.

Honda Confirms Closure of UK Car Plant

Honda has confirmed its western England car factory, which employs 3,500 people, will close in 2021.

The Japanese carmaker announced Monday that the Swindon plant will shut in two years, “at the end of the current model’s production life cycle.”

 

Honda makes its popular Civic model at the factory, 70 miles (115 kms) west of London.

 

Reports of the closure first emerged in February, heightening concerns about the impact of Brexit-related uncertainty on the U.K. economy.

 

Honda said the closure is not Brexit-driven but “is part of Honda’s broader global strategy in response to changes to the automotive industry.”

 

It said it had spoken to the British government and union consultants, but “no viable alternatives to the proposed closure of the Swindon plant have been identified.”

 

Technology Creates Virtual Wall Around Wildlife Preserve

South Africa, which has the largest population of rhinos in the world, has been the country hit hardest by poaching. Between 2007 and 2015, there was a 9,000% increase in poaching there, reaching a high of 1,215 animals in 2014. While numbers have been declining since then, poaching remains a problem. But as Faith Lapidus reports, technology is helping turn one game reserve into a high-tech fortress.

US Expects China Tariff Retaliation

The U.S. said Sunday it expects that China will retaliate with increased tariffs on U.S. exports after President Donald Trump sharply boosted levies on Chinese products headed to the United States.

Chief White House economic adviser Larry Kudlow told “Fox News Sunday” that “both sides will suffer” from the escalating trade war between the U.S. and China, the world’s two biggest economies.

In the U.S., he said that “maybe the toughest burdens” are on farmers who sell soybeans, corn and wheat to China. But he said the Trump administration has “helped them before on lost exports” with $12 billion in subsidies and that “we’ll do it again if we have to and if the numbers show that out.”

Trump on Friday more than doubled tariffs on $200 billion of Chinese goods, boosting the rate from 10 percent to 25 percent, while also moving to impose tariffs on an additional $300 billion of Chinese products, although Kudlow said it could take months for the full effect of the tariffs to be felt. China had previously imposed taxes on $110 billion of American products, but has not said how it might retaliate against Trump’s latest increase in tariffs.

Trade talks between the two economic super powers have been going on in Beijing and Washington for months, but they recessed again in the U.S. capital on Friday without a deal being reached.

“We were moving well, constructive talks and I still think that’s the case,” Kudlow said. “We’re going to continue the talks as the president suggested.”

Kudlow said Trump and Chinese President Xi Jinping are likely to discuss trade issues at the G-20 summit in Japan at the end of June.

The economic adviser renewed U.S. claims that China had backtracked from earlier agreements reached in the talks, forcing negotiators to cover “the same ground this past week.”

“You can’t forget this: This is a huge deal, the broadest scope and scale…. two countries have ever had before,” Kudlow said. “But we have to get through a lot of issues. For many years, China trade was unfair, non-reciprocal, unbalanced in many cases, unlawful.”

The U.S. has claimed that China steals technology and forces U.S. companies to divulge trade secrets it uses in its own production of advanced technology products.

On Saturday, Trump suggested that China could be waiting to see if he wins reelection next year, but said Beijing would be “much worse” off during a second term of his in the White House.

“I think that China felt they were being beaten so badly in the recent negotiation that they may as well wait around for the next election, 2020, to see if they could get lucky & have a Democrat win,” he said, “in which case they would continue to rip-off the USA for $500 Billion a year.”

“Such an easy way to avoid Tariffs?” the U.S. leader said, “Make or produce your goods and products in the good old USA. It’s very simple!”

 

 

 

 

 

 

13-Year-Old ‘CyberNinja’ Hacks Drone to Show Cyber Threat

President Donald Trump signed an executive order this month designed to strengthen the country’s cybersecurity workforce, the front line against hackers, domestic and foreign. With 7 billion internet-connected devices in the world, and numbers expected to rise, the threat is growing. Faith Lapidus reports, web-connected devices, from smart homes to drones, are vulnerable.

Trump Has Long Seen Previous US Trade Agreements as Losers

President Donald Trump’s combative approach to trade has been one of the constants among his often-shifting political views. And he’s showing no signs of backing off now, even as the stakes intensify with the threat of a full-blown trade war between the world’s two biggest economies.  

  

The president went after China on Day 1 of his presidential bid, promising to “bring back our jobs from China, from Mexico, from Japan, from so many places.” 

 

Trump’s views on trade helped forge his path to victory in states such as Pennsylvania, Michigan, Wisconsin and Ohio, where he linked the loss of manufacturing jobs to the North America Free Trade Agreement and other trade deals. He warned the worst was yet to come with President Barack Obama’s proposed Trans-Pacific Partnership.  

  

His trashing of existing and proposed trade agreements grabbed the headlines, but he also made clear his view that globalization had been bad for America and that he would use tariffs to protect national security and domestic producers. He cited the nation’s Founding Fathers, Abraham Lincoln and Ronald Reagan as leaders whose footsteps he was following when it came to trade and tariffs. 

 

Our original Constitution did not even have an income tax,'' Trump told voters in Monessen, Pa., four months before the 2016 presidential election.Instead, it had tariffs, emphasizing taxation of foreign, not domestic production.” 

​Taking on China

 

No. 7 on his list of trade promises in that speech: taking on China for “its theft of American trade secrets.” 

 

“This is so easy. I love saying this. I will use every lawful presidential power to remedy trade disputes, including the application of tariffs consistent” with existing trade laws, Trump said. 

 

Those laws include Section 232 of the Trade Expansion Act, which Trump cited to enact tariffs on steel and aluminum imports from China, Canada, Mexico and elsewhere. 

 

They also include Section 301 of the Trade Act, which Trump used last year to apply 25 percent tariffs on $50 billion worth of Chinese goods and 10 percent tariffs on $200 billion of goods. That 10 percent was increased to 25 percent on Friday. Trump is laying the groundwork to extend the 25 percent tariff to all of China’s exports to the U.S. 

 

“Such an easy way to avoid Tariffs? Make or produce your goods and products in the good old USA. It’s very simple!” Trump tweeted on Saturday. 

 

Of course, America’s trading partners haven’t let Trump’s tariffs stand without taking similar action themselves. Farmers, boat makers, and whiskey and wine producers are just some of the U.S. industries caught in the middle. 

 

Farming is a very small-margin, small-profit business. We rely on lots of volume and lots of sales to generate a profit,'' said Brent Bible, a soybean and corn farmer in Lafayette, Ind., who has seen prices for both commodities drop in the past year.We are operating at a loss now.” 

 

Trump’s philosophy on some issues has evolved over the years. 

 

He once described himself regarding the abortion issue as very pro-choice.'' Now, his administration promotes him as the mostpro-life president in American history.” 

​Complaint about Japan

 

On trade, not so much. In Trump: The Art of the Deal, Trump complained of the Japanese that “what’s unfortunate is that for decades now they have become wealthier in large measure by screwing the United States with a self-serving trade policy that our political leaders have never been able to fully understand or counteract.” 

 

Fast-forward nearly three decades, and Trump declared in his 2015 announcement for the presidency that other nations were prospering at America’s expense. “When was the last time anybody saw us beating, let’s say, China, in a trade deal? They kill us. I beat China all the time,” Trump said. 

 

Trump’s approach on trade is a dramatic departure for the Republican Party, but GOP lawmakers have declined to take action that would block his tariffs. They credit his tactics for getting improvements to a trade deal with Canada and Mexico to replace NAFTA, and for getting China to the negotiating table. 

 

President Trump is the first president to take China head-on,'' said Texas Rep. Kevin Brady, the top Republican on the House Ways and Means Committee. He saideveryone knows I’m not a fan of tariffs, but I think everyone knows as well that China has been cheating for far too long.” 

 

Trump has received some encouragement from Democratic leaders. Senate Minority Leader Chuck Schumer, D-N.Y., tweeted to Trump: “Don’t back down. Strength is the only way to win with China.” 

 

Current and former officials in the administration believe that voters will give the president credit for standing up to China, and not blame him for any pain that may result from the tariffs war. 

 

Overall, AP VoteCast found Americans critical in their assessments of Trump on trade. But that’s not the case with his supporters. According to the survey of more than 115,000 midterm voters nationwide, 45% approved of Trump on trade, while 53% disapproved. Among voters who approved of Trump’s job overall, fully 88% approved of his handling of trade. 

​Who pays?

 

While Trump casts his tariffs as being paid for by China, they actually are paid by the American companies that bring a product into the U.S. This can help some U.S. producers, though, because it makes their goods more competitive pricewise. Still, the burden of Trump’s tariffs on imports from China and other countries falls entirely on U.S. consumers and businesses that buy imports, said a study in March by economists from the Federal Reserve Bank of New York, Columbia University and Princeton University. 

 

Republican-leaning business groups such as the U.S. Chamber of Commerce have warned that the tariffs threaten to derail the economy raise unemployment, but with economic growth at 3.2 percent last quarter and the unemployment rate at 3.6 percent, Trump isn’t changing strategy now. 

 

“Tariffs will make our Country MUCH STRONGER, not weaker. Just sit back and watch!” Trump tweeted on Friday. 

Officials Probe Alarming HIV Outbreak in Southern Pakistan

Officials in Pakistan and the United Nations are investigating causes of a new outbreak of HIV infections in a southern district where nearly 400 people have been diagnosed in less than two weeks. Officials confirmed Saturday that nearly 80% of those infected are children, with nearly half of them under age 5.

Local media began reporting about the epidemic two weeks ago from Larkana, a district of Sindh province, which has already experienced three outbreaks in recent years. A local doctor who treated several patients with a single needle and syringe was blamed for spreading the virus, which causes AIDS. 

 

The provincial government rushed teams of public health workers to the district, with an estimated population of 1.5 million, to quickly assess the situation and mobilize resources to curtail further spread of HIV. More than 9,000 people have since been subjected to screening in the affected district, and the process is continuing, Sikandar Memon, the provincial head of the AIDS Control Program, told reporters.

 

A UNAIDS spokeswoman told VOA that international partners had joined local teams to help quickly carry out an outbreak investigation and address the acute needs of the people infected with HIV, including immediately linking them to treatment, care and support services. 

 

The spokeswoman, Fahmida Khan, said efforts were being made to ensure that unsafe injection and blood transfusion practices were being stopped. She also noted that there were unconfirmed reports of similar HIV outbreaks in surrounding districts. 

​Focus of problem

Sindh, with a population of nearly 48 million, accounts for 43% of an estimated 150,000 people living with HIV in Pakistan. 

 

U.N. officials say since 2010, there has been a 57% increase in new HIV/AIDS infections in Pakistan. They noted that among all identified HIV cases in Pakistan, 43,000 are females. 

Last year, an estimated 20,000 people were newly identified with HIV in Pakistan and 6,200 people died of AIDS, according to local and U.N. officials. 

 

Khan would not comment on the reasons for the high number of HIV infections among children and the potential causes of the latest outbreak in Larkana, saying “further investigations and epidemiological review is yet required and suggested.” 

 

Provincial authorities also have launched a high-level investigation to ascertain the veracity of the allegations against the local doctor, who already has been taken into police custody. 

Some also blame unsafe injection practices by quack doctors for contributing to the spread of HIV. Government officials estimate about 600,000 unqualified doctors are unlawfully operating in Pakistan and 270,000 of them are practicing in Sindh. 

 

Critics also blame lapses in Pakistan’s national health system, the low priority given to the problem, corruption, the recent abolition of the federal health ministry and the delegation of its functions to the provinces for the worsening health sector situation and the increase in HIV infections. 

Pakistani and U.N. officials say the HIV epidemic in Pakistan remains largely concentrated among key populations, including people who inject drugs, the transgender community, sex workers and their clients, and men who have sex with men.

Landmark UN Plastic Waste Pact Gets Approved But Not by US

Nearly every country in the world has agreed upon a legally binding framework to reduce the pollution from plastic waste except for the United States, U.N. environmental officials say.

An agreement on tracking thousands of types of plastic waste emerged Friday at the end of a two-week meeting of U.N.-backed conventions on plastic waste and toxic, hazardous chemicals.

Discarded plastic clutters pristine land, floats in huge masses in oceans and rivers and entangles wildlife, sometimes with deadly results.

Rolph Payet of the United Nations Environment Program said the “historic” agreement linked to the 186-country, U.N.-supported Basel Convention means that countries will have to monitor and track the movements of plastic waste outside their borders.

The deal affects products used in a broad array of industries, such as health care, technology, aerospace, fashion, food and beverages.

“It’s sending a very strong political signal to the rest of the world — to the private sector, to the consumer market — that we need to do something,” Payet said. “Countries have decided to do something which will translate into real action on the ground.”

Countries will have to figure out their own ways of adhering to the accord, Payet said. Even the few countries that did not sign it, like the United States, could be affected by the accord when they ship plastic waste to countries that are on board with the deal.

Payet credited Norway for leading the initiative, which first was presented in September. The time from that proposal to the approval of a deal set a blistering pace by traditional U.N. standards for such an accord.

The framework “is historic in the sense that it is legally binding,” Payet said. “They (the countries) have managed to use an existing international instrument to put in place those measures.”

The agreement is likely to lead to customs agents being on the lookout for electronic waste or other types of potentially hazardous waste more than before.

“There is going to be a transparent and traceable system for the export and import of plastic waste,” Payet said.

 

US Hospital Tests Promising Treatment for Alzheimer’s

Dementia is a rapidly growing public health problem around the world. Fifty million people suffer from dementia, and in the next 30 years, that number is expected to triple.

Researchers are looking for ways to treat or prevent dementia, and a promising clinical trial is underway in the U.S.

Dementia is not a normal part of aging, but age is a huge risk factor. Regular exercise, a healthy diet, maintaining healthy blood pressure, cholesterol, and blood sugar levels help stave off dementia as we grow older

As people around the world live longer, health agencies and researchers are looking for ways to prevent, stop or treat dementia, including Alzheimer’s disease, one of the most common types of dementia.

Promising clinical trial

David Shorr was diagnosed with Alzheimer’s at 56.He is about to undergo a new procedure that could treat early stage Alzheimer’s. He is with his doctor, Vibhor Krishna, a neurosurgeon at Ohio State Wexner Medical Center.

The procedure Shorr is about to have involves sound waves. Ultrasound waves target and open the blood-brain barrier — a protective layer that shields the brain from infections. But Krishna says the barrier also makes it hard to treat neurodegerative diseases like Alzheimer’s.

“Opening the blood-brain barrier allows us to access more of the brain tissue and be able to increase the effectiveness or bioavailability of the therapeutics,” Krishna said.

Shorr and his wife, Kim, were willing to try any new treatment that might help with his dementia. Kim describes the couple’s reaction when they received a phone call inviting Shorr to participate in a clinical trial.

“There’s this trial. Would you be interested?” she said, describing the call. “And without really knowing what it was, we said, Sure.’”

Ultrasound targets protein buildup

Shorr became one of 10 patients enrolled in the study. The trial tests MRI-guided imaging to target the part of the brain responsible for memory and cognition. Krishna explains that’s where Alzheimer’s patients have a buildup of toxic proteins called amyloid.

“Higher deposition of amyloid goes hand in hand with loss of function in Alzheimer’s disease,” he said.

Krishna says this procedure might allow a patient’s own immune system to clear some of the amyloid.

In this procedure, ultrasound wave pulses cause microscopic bubbles to expand and contract in the brain.

“The increase and decrease in size of these microbubbles mechanically opens the blood-brain barrier,” Krishna said.

The patient is awake during the procedure.

Study could help others

Opening the barrier may one day allow doctors to deliver medication straight to the site of the disease.

Kim Shorr realizes her husband might not benefit from this treatment.

“We’re hopeful it can help him, but we also know maybe it will help somebody else,” she said.

Shorr is glad to be part of a study that could help others who are in the early stages of Alzheimer’s, even if it doesn’t help him.

Ebola Outbreak Could Spiral Beyond DRC, WHO Warns

Contributors include Erikas Mwisi reporting from Beni, North Kivu; Margaret Basheer from the United Nations; and Eddy Isango, James Butty and Carol Guensburg from Washington.

Armed attacks, misinformation and a growing funding gap continue to impede the response to the Ebola outbreak in northeastern Democratic Republic of Congo, with the World Health Organization warning that the situation could spiral out of control.

Insecurity leaves response teams “unable to perform robust surveillance nor deliver much needed treatment and immunizations,” the WHO reported Friday in its latest update on the outbreak confirmed last August. The health organization warned that “without commitment from all groups to cease these attacks, it is unlikely that this EVD [Ebola virus disease] outbreak can remain successfully contained in North Kivu and Ituri provinces.”

The disease could spill into other parts of the country and across the borders of neighboring Uganda, Rwanda and South Sudan, the health organization suggested.

This month alone has brought setbacks such as a violent assault on a burial team in the town of Katwa and a gunfight between at least 50 armed militia and security forces in the city of Butembo, WHO reported. Mourners also buried Richard Valery Mouzoko Kiboung, a 41-year-old Cameroonian doctor killed April 19 while working for WHO and meeting with other front-line workers at Butembo University Hospital.

The threats continue.

On Thursday, a VOA correspondent in Butembo saw a series of letters scattered on a street, each weighted down with pebbles. Written in Swahili and attributed to Mai-Mai fighters, the letters warned police, soldiers and the general public against showing any support for Ebola responders or treatment centers. 

Anderson Djumah, whose 10-year-old son is being treated for Ebola at the general hospital in the North Kivu town of Beni, complained that “the lack of security has just added more suffering.”

“Even Ebola treatment centers are targeted by the assailants. We’re afraid. Ebola is killing so many people. We’re still expecting that the government would be able to protect us,” he said. “… [But] some people who are sick with Ebola are fleeing to other places for their lives and are meanwhile spreading the sickness.”

Complications for care

Violence sends people into hiding and disrupts response operations such as contact tracing, vaccination and safe burials, giving “time and space to the virus to spread within the community and make more victims,” Jessica Ilunga, spokeswoman for the DRC’s health ministry, told VOA.

“Every time we have a security incident, the number of cases and deaths obviously increases,” Ilunga said.

The health ministry, leading the response with WHO’s help, reported 1,600 total cases as of Wednesday, with 1,534 confirmed and 66 likely. This second-worst Ebola outbreak already has claimed 1,069 lives. The 2014-15 West African outbreak killed more than 11,000.

Many of the victims have died at home, potentially exposing others to the disease and leaving gaps in how — and to whom — the virus may have been transmitted.

“You don’t know who those contacts are,” said epidemiologist Jennifer Nuzzo, an epidemiologist and principal investigator for the Outbreak Observatory, a project of the Johns Hopkins Center for Health Security. “… Chances are you can’t offer them vaccines or treatment.”

Funding for the Ebola response has fallen far short of need, WHO spokesman Tarik Jasarevic said in an email to VOA Wednesday. As of May 2, WHO had received $32.5 million of the $87 million it estimated needing for six months ending in July.

“If the funds are not received,” Jasarevic wrote, “WHO will be unable to sustain the response at the current scale.” 

​New challenges in 10th DRC outbreak

This is the DRC’s 10th reported outbreak since the virus’ discovery near the Ebola River in 1976. The country has proved adept at snuffing out past outbreaks of Ebola, which has been found in bats, monkeys and other animals sometimes consumed as “bush meat.” The virus spreads through contact with an infected person’s body fluids.

Ebola was unfamiliar in the northeast, a region already destabilized by at least two decades of conflict. More than 100 armed groups roam the area, displacing hundreds of thousands of people.

High mobility and population density also raise the potential that the virus could cross into Uganda, Rwanda and South Sudan. (The U.S. Centers for Disease Control and Prevention has been providing technical guidance to the DRC and its neighbors, for instance, helping them ramp up surveillance and vaccination tracking.)

Wary public

Skepticism also factors into the Ebola equation. The northeast is an opposition stronghold, and its residents were angered to be kept from voting in December’s general elections, as former U.S. diplomat John Campbell pointed out in a Council on Foreign Relations blog post.

A study published in The Lancet medical journal in March found low public trust in local authorities and broad acceptance of misinformation about Ebola. Just a third of the 961 respondents — adults surveyed in North Kivu’s Beni and Butembo last fall — said they had confidence that local authorities acted in the public interest. A fourth indicated they didn’t believe Ebola exists.

Mistrust and misinformation make it less likely that individuals will heed public safety directives, such as accepting Ebola vaccines, seeking formal medical care or supporting safe burial practices, the researchers noted.

That mistrust can be weaponized, as Medecins Sans Frontieres/Doctors Without Borders experienced. Two of the international aid group’s Ebola treatment centers, in Katwa and Butembo, were attacked in February. MSF suspended services there, saying its ability to respond in the outbreak’s epicenter had been “crippled.” 

Anne-Marie Pegg, MSF’s clinical lead for epidemic response, said some Congolese look critically at the disparity between local clinics, which, if they exist, might lack basics such as running water and electricity, and the better-equipped Ebola treatment centers set up by international aid groups.

“Very little investment has gone into the existing health structures and the existing health system, and people notice this,” Pegg said. She said MSF, in “numerous interactions,” has heard complaints that international groups are involved “‘only because we [locals] are contagious and we’re a threat to you.’

“It’s not surprising that something like Ebola can be manipulated for any variety of reasons,” Pegg added. “… Absolutely, there are interest groups from all sides that are trying to use this.”

MSF continues to work in the region while pressing for “better integration of Ebola treatment into the health care system,” Pegg said. The virus’ early symptoms, such as headaches and muscle pain, are indistinguishable from those of malaria or other more common ailments, so “it’s difficult for someone who’s sick to think, ‘I have Ebola.’ So the capacity to isolate someone who may have an Ebola infection and test for that … needs to happen at a local level” rather than sending patients to a treatment center. “It would be nice if those people could be treated closer to home” and started on treatment while awaiting test results. If the virus is confirmed, then transfer the patient to an Ebola treatment center, “which is the best place.”

But, she said, MSF’s goal is to treat whatever ailment a patient might have.

​Vaccine plans revised

As Ebola infections rise, a WHO advisory group this week recommended that an approved vaccine be distributed more widely in smaller doses and that an experimental vaccine, developed by Johnson & Johnson, also be offered. More than 100,000 doses of the approved Merck vaccine have been distributed since August, but supplies are running low. The dosage would be halved from the current 1 milliliter for the primary and secondary “ring vaccination,” which prescribes inoculation for anyone in contact with an infected person. Eligibility would be expanded through “pop-up and targeted geographic approaches” in high-risk areas.

“We know that vaccination is saving lives in this outbreak,” WHO Director-General Tedros Adhanom Ghebreyesus said in a statement.

The advisory group also recommended more training for local health workers.

Space Tourism Steps Closer to Commercial Flight Reality

Billionaire Richard Branson is moving Virgin Galactic’s winged passenger rocket and more than 100 employees from California to a remote commercial launch and landing facility in southern New Mexico, bringing his space tourism dream a step closer to reality.

Branson said Friday at a news conference that Virgin Galactic’s development and testing program has advanced enough to make the move to the custom-tailored hangar and runway at the taxpayer-financed Spaceport America facility near the town of Truth or Consequences.

Virgin Galactic CEO George Whitesides said a small number of flight tests are pending. He declined to set a specific deadline for the first commercial flight.

An interior cabin for the company’s space rocket is being tested, and pilots and engineers are among the employees relocating from California to New Mexico. The move to New Mexico puts the company in the “home stretch,” Whitesides said.

The manufacturing of the space vehicles by a sister enterprise, The Spaceship Company, will remain based in the community of Mojave, California.

​Taxpayer backing

Taxpayers invested more than $200 million in Spaceport America after Branson and then-Gov. Bill Richardson, a Democrat, pitched the plan for the facility, with Virgin Galactic as the anchor tenant.

Virgin Galactic’s spaceship development has taken far longer than expected and had a major setback when the company’s first experimental craft broke apart during a 2014 test flight, killing the co-pilot.

Branson thanked New Mexico politicians and residents for their patience over the past decade. He said he believes space tourism — once aloft — is likely to bring about profound change.

“Our future success as a species rests on the planetary perspective,” Branson said. “The perspective that we know comes sharply into focus when that planet is viewed from the black sky of space.”

Branson described a vision of hotels in space and a network of spaceports allowing supersonic, transcontinental travel anywhere on earth within a few hours. He indicated, however, that building financial viability comes first.

“We need the financial impetus to be able to do all that,” he said. “If the space program is successful as I think … then the sky is the limit.”

​Gushing passenger

In February, a new version of Virgin Galactic’s winged craft SpaceShipTwo soared at three times the speed of sound to an altitude of nearly 56 miles (99 kilometers) in a test flight over Southern California, as a crew member soaked in the experience.

On Friday, that crew member, Beth Moses, recounted her voyage into weightlessness and the visual spectacle of pitch-black space and the earth below.

“Everything is silent and still and you can unstrap and float about the cabin,” she said. “Pictures do not do the view from space justice. … I will be able to see it forever.”

The company’s current spaceship doesn’t launch from the ground. It is carried under a special plane to an altitude of about 50,000 feet (15,240 meters) before detaching and igniting its rocket engine.

“Release is like freefall at an amusement park, except it keeps going,” Moses said. “And then the rocket motor lights. Before you know it, you’re supersonic.”

First commercial flight may be this year

The craft coasts to the top of its climb before gradually descending to earth, stabilized by “feathering” technology in which twin tails rotate upward to increase drag on the way to a runway landing.

Branson previously has said he would like to make his first suborbital flight this year as one of the venture’s first passengers on the 50th anniversary of the Apollo 11 moon landing on July 20. But he made no mention of timelines on Friday.

Pressed on the timeframe, Whitesides said he anticipates the first commercial flight within a year.

Three people with future space-flight reservations were in the audience.

“They’ve been patient, too,” Branson said. “Space is hard.”

Hundreds of potential customers have committed as much as $250,000 up front for rides in Virgin’s six-passenger rocket, which is about the size of an executive jet.

Virgin not alone

Other Branson’s plans have gradually advanced amid a broader surge in private investment in space technology with cost-saving innovations in reusable rockets and microsatellite technology.

Amazon tycoon Jeff Bezos announced Thursday that his space company, Blue Origin, will send a robotic spaceship to the moon with aspirations for another ship that could bring people there along the same timeframe as NASA’s proposed 2024 return. Bezos has provided no details about launch dates.

AP Fact Check: Trump’s Tweets on Trade Battle With China 

President Donald Trump let loose with a morning round of tweets Friday that downplayed the possible consequences of his trade war with China.   

   

Trump minimized the worth of China’s purchases of U.S. goods and services, which support nearly 1 million jobs in the U.S.; misstated the trade deficit; and ignored the inevitable rise in many costs to consumers when imports are heavily taxed.  

 

The tweets came as his tariffs kicked in on $200 billion worth of Chinese goods, with another round of tariffs in the offing, and as U.S. and Chinese officials negotiated in Washington. With trade relations between the economic giants seemingly rupturing and the stock market sinking, Trump called the talks “congenial.”  

 

A look at some of his statements:  

 

Trump: “Your all time favorite President got tired of waiting for China to help out and start buying from our FARMERS, the greatest anywhere in the World!”  

 

The facts: The notion that China doesn’t buy from U.S. farmers is false. China is the fourth-largest export market for U.S. agriculture. It bought $9.3 billion in U.S. agricultural products last year.  

 

As for calling himself “your” favorite president, polls find Trump’s approval rating to be high among Republicans, but it generally ranges between 35% and 45% among Americans overall.   

 

Trump: “We have lost 500 Billion Dollars a year, for many years, on Crazy Trade with China. NO MORE!”  

 

The facts: That’s wrong. When sizing up the trade deficit, Trump always ignores trade in services — where the U.S. runs a surplus with China — and speaks only of goods. Even in that context, he misstated the imbalance.  

 

The U.S. trade deficit with China last year was $378.6 billion, not $500 billion. On goods alone, the deficit was $419.2 billion.      

Trump is also misleading when he puts the deficit in that ballpark for many years. It’s true that the imbalance has long been lopsided, but the U.S. trade representative’s office notes that exports of goods to China have increased by nearly 73% since 2008 and U.S. exports to China overall are up 527% since 2001.  

 

Nor is the trade gap a “loss” in a pure sense. U.S. consumers and businesses get electronics, furniture, clothing and other goods in return for their money. They are buying things, not losing cash.  

Trump: “Tariffs are NOW being paid to the United States by China of 25% on 250 Billion Dollars worth of goods & products. These massive payments go directly to the Treasury of the U.S.”  

 

The facts: This is not how tariffs work. China is not writing a check to the U.S. Treasury. The tariffs are paid by American companies, which usually pass the cost on to consumers through higher prices. One theory in support of such tariffs is that higher prices for Chinese imports will encourage consumers to buy goods made in the U.S. or elsewhere instead. But the risk is that consumers could simply respond by spending less than they otherwise would, which would hurt growth. 

The burden of Trump’s tariffs on imports from China and other countries falls entirely on U.S. consumers and businesses that buy imports, said a study in March by economists from the Federal Reserve Bank of New York, Columbia University and Princeton University. By the end of last year, the study found, the public and U.S. companies were paying $3 billion a month in higher taxes and absorbing $1.4 billion a month in lost efficiency.  

 

A coalition of U.S. trade organizations representing retail businesses, tech, manufacturing and agriculture said this week: For 10 months, Americans have been paying the full cost of the trade war, not China.'' It said:To be clear, tariffs are taxes that Americans pay, and this sudden increase with little notice will only punish U.S farmers, businesses and consumers.” 

 

Trump: “Tariffs will bring in FAR MORE wealth to our Country than even a phenomenal deal of the traditional kind. Also, much easier & quicker to do. Our Farmers will do better, faster, and starving nations can now be helped. Waivers on some products will be granted, or go to new source!”  

 

The facts: In addition to repeating the canard that China pays the tariffs, he’s failing to account for the damage that tariffs can do.  

 

By most private estimates, a trade war leads to slower growth rather than the prosperity that Trump is promising. The president’s tweet also goes beyond past claims that tariffs are simply a negotiating tactic to force better terms with China. Trump appears to be suggesting that a tariff increase would generate revenues that could then be spent on farm products and infrastructure, something that might in theory require support from Congress.  

 

But on their own, tariffs are a clear drag on growth.  

 

Analysts at the consultancy Oxford Economics estimate that implementing and maintaining the latest increase would trim U.S. gross domestic product by 0.3%, or $62 billion, in 2020. This would be equal to a loss of about $490 per household.  

 

Economists at Nomura note that gross domestic product this year could take a hit of as much as 0.4% if Trump expands the taxes to all Chinese imports, as business confidence slumped and financial conditions tightened. 

Why Does Facebook Fail to Fix Itself? It’s Partly Humans

The question comes up over and over, with extremist material, hate speech, election meddling and privacy invasions. Why can’t Facebook just fix it?

It’s complicated, with reasons that include Facebook’s size, its business model and technical limitations, not to mention years of unchecked growth. Oh, and the element of human nature.

The latest revelation: Facebook is inadvertently creating celebratory videos using extremist content and auto-generating business pages for the likes of Islamic State and al-Qaida. The company says it is working on solutions and the problems are getting better. That is true, but critics say better is not good enough when mass shootings are being live-streamed and online mobs are spreading rumors that lead to deadly violence.

“They have been frustratingly slow in dealing with everything from child sexual abuse to terrorism, white supremacy, bullying, nonconsensual porn” and things like allowing advertisers to target categories such as “Jew hater,” simply because some users had listed the term as an “interest,” said Hany Farid, a digital forensics expert at the University of California, Berkeley.

As new problems crop up, Facebook’s formula has been to apologize and promise to make changes, sometimes also noting that it did not anticipate how malicious actors could so readily misuse its platform. More recently, the company has also emphasized just how much it is improving, both technically in its use of artificial intelligence to detect problems and in terms of focusing more money and effort on fixing them.

“After making heavy investments, we are detecting and removing terrorism content at a far higher success rate than even two years go,” Facebook said Wednesday in response to the revelations about the auto-generated pages. “We don’t claim to find everything, and we remain vigilant in our efforts against terrorist groups around the world.”

It has seen some success. In late 2016, CEO Mark Zuckerberg infamously dismissed as “pretty crazy” the idea that fake news on his service could have swayed the election. He later backtracked, and since then the company has reduced the amount of misinformation shared on its service, as measured by several independent studies.

Zuckerberg has also, by and large, avoided similar gaffes by conceding mistakes and delivering apologies to the public and to lawmakers.

‘Stuck with all this garbage’

But even as the company bats down one problem, others pop up. The reason for that might be baked into its DNA. And that’s not just because its business model relies on as many people as possible using it as much as possible, leaving behind personal details that can then be targeted by advertisers.

“Almost everything Facebook has designed has been designed for good people. People who are nice to each other, who have birthdays to celebrate, who have new puppies and generally like to treat others well,” said Siva Vaidhyanathan, director of the Center for Media and Citizenship at the University of Virginia. “Basically Facebook is made for a better species than ours. If it were made for golden retrievers, everything would be great.”

But if just 1% of the 2.4 billion people on Facebook want to do terrible things to others, that’s 24 million people.

“Every couple of weeks, we hear about Facebook knocking down troublesome pages, making promises about hiring more people, building AI and so on,” Vaidhyanathan said. “But at Facebook’s scale, none of that will matter. We are basically stuck with all this garbage.”

Chris Hughes, a co-founder of Facebook, called for a breakup of the social media giant in a Thursday op-ed. Vaidhyanathan also thinks strong government regulation could be the answer, such as laws that “limit companies’ ability to suck up all our data and use it to target advertising.”

“We really should be addressing the back end of Facebook,” he said. “That’s what you have to attack.”

France Welcomes Facebook’s Zuckerberg With Threat of New Rules

France welcomed Facebook’s Mark Zuckerberg on Friday with a threat of sweeping new regulation.

With Facebook under fire on multiple fronts, Zuckerberg is in Paris to show that his social media giant is working hard to limit violent extremism and hate speech shared online.

But a group of French regulators and experts who spent weeks inside Facebook facilities in Paris, Dublin and Barcelona say the company isn’t working hard enough.

Just before Zuckerberg met French President Emmanuel Macron in Paris, the 10 officials released a report calling for laws allowing the government to investigate and fine social networks that don’t take responsibility for the content that makes them money.

The French government wants the legislation to serve as a model for Europe-wide management of social networks. Several countries have introduced similar legislation, some tougher than what France is proposing.

To an average user, it seems like the problem is intractable. Mass shootings are live-streamed, and online mobs are spreading rumors that lead to deadly violence. Facebook is even inadvertently creating celebratory videos using extremist content and auto-generating business pages for the likes of the Islamic State group and al Qaida.

The company says it is working on solutions, and the French regulators praised Facebook for hiring more people and using artificial intelligence to track and crack down on dangerous content.

But they said Facebook didn’t provide the French officials enough information about its algorithms to judge whether they were working, and that a “lack of transparency … justifies an intervention of public authorities.”

The regulators recommended legally requiring a “duty of care” for big social networks, meaning they should moderate hate speech published on their platforms. They insist that any law should respect freedom of expression, but did not explain how Facebook should balance those responsibilities in practice.

After meeting Macron, Zuckerberg said in a Facebook post that he welcomed governments taking a more active role in drawing up regulations for the internet. He made similar remarks earlier this year but has been vague on what kind of regulation he favors.

Facebook faces “nuanced decisions” involving content that is harmful but not illegal and the French recommendations, which set guidelines for what’s considered harmful, “would create a more consistent approach across the tech industry and ensure companies are held accountable for enforcing standards against this content,” Zuckerberg said.

The regulators acknowledged that their research didn’t address violent content shared on private chat groups or encrypted apps, or on groups like 4chan or 8chan, where criminals and extremists and those concerned about privacy increasingly turn to communicate.

Facebook said Zuckerberg is in France as part of meetings around Europe to discuss future regulation of the internet. Facebook agreed to embed the French regulators as an effort to jointly develop proposals to fight online hate content.

Zuckerberg’s visit comes notably amid concern about hate speech and disinformation around this month’s European Parliament elections.

Next week, the leaders of France and New Zealand will meet tech leaders in Paris for a summit seeking to ban acts of violent extremism and terrorism from being shown online.

Facebook has faced challenges over privacy and security lapses and accusations of endangering democracy — and it came under criticism this week from its own co-founder.

Chris Hughes said in a New York Times opinion piece Thursday that it’s time to break up Facebook. He says Zuckerberg has turned Facebook into an innovation-suffocating monopoly and lamented the company’s “slow response to Russian agents, violent rhetoric and fake news.”

Invasive Species Causing Environmental Decline, New Report Warns

The United Nations released a new global report on the environment this week. It says the decline of nature is unprecedented, and species extinction is accelerating. The study warns that many factors are having a severe impact, including climate change, pollution, deforestation, and invasive plants and animals. In South Africa, the Garden Route National Park is located along one of the country’s most beautiful stretches of coastline. It is also a place where a large number of invasive plants have taken over. VOA’s Deborah Block takes us there to find out how officials are working to keep them at bay.

Ebola Could Spread Elsewhere if Attacks Don’t Stop, WHO Warns

The World Health Organization warned Friday that it may not be possible to contain Ebola to the two affected provinces in eastern Congo if violent attacks on health teams continue.

The ominous statement comes amid escalating violence nine months after the outbreak began, crippling efforts to identify suspected cases in the community and vaccinate those most at risk. Earlier this week, Mai-Mai militia fighters attacked the town of Butembo at the epicenter of the crisis. 

 

Friday’s update also noted that a burial team had been “violently attacked” after they interred an Ebola victim in the town of Katwa. The corpses of victims are highly contagious, requiring special precautions to ensure the disease is not transmitted at funerals.

Nearly five days of Ebola response activities were halted in Butembo and surrounding areas recently because of the insecurity, WHO said.

“The ongoing violent attacks sow fear, perpetuate mistrust, and further compound the multitude of challenges already faced by frontline health care workers,” it said. “Without commitment from all groups to cease these attacks, it is unlikely that this (Ebola) outbreak can remain successfully contained in North Kivu and Ituri provinces.”

The outbreak, which has killed 1,069 people, marks the first time that Ebola has struck inside a conflict zone. Eastern Congo has suffered decades of violence perpetrated by warring rebel groups and militias awash in arms. 

 

The affected area, though, is also close to Congo’s borders with Uganda and Rwanda, and health officials in both countries have been preparing in case someone sick with Ebola should bring the disease across international borders.

WHO efforts

WHO and others have previously said that the risk of that happening was low. The difficulties in accessing some of the hardest hit areas in Congo, though, means that health workers are struggling to isolate the sick, and track down and isolate their caregivers and family members. 

 

About half of those dying remained in their homes instead of seeking treatment at Ebola health centers, giving the virus an opportunity to spread to those in physical contact with victims.

Amid the rising number of cases, WHO said Friday that an advisory group was now recommending that those at high risk of contracting Ebola be given a vaccine dose of 0.5mL of vaccine instead of 1mL. The group is proposing that the vaccine be given more widely, including to those living in communities where there have been recent Ebola cases.

In addition to the risks posed by militias there also has been widespread community mistrust in eastern Congo, a byproduct of years of conflict and grievances with the government. WHO said it was aiming to have the majority vaccine teams comprised of local health workers by the end of the month in an effort to reduce tensions. 

Your Uber Has Arrived, on Wall Street

With a ring of the opening bell, Uber began picking up passengers as a newly minted public company Friday and investors waited to bet on a service with huge potential, but a long way from turning a profit.

Shares in the ride-hailing giant were sold in an initial public offering for $45 each, raising $8.1 billion, but it will take several hours for new investors to show how much they’re interested. Officials expect trading to start around 11:30 a.m.

CEO Dara Khosrowshahi and other company officials stood on a balcony above the New York Stock Exchange and clapped as the bell rang to signal the start of the day’s trading.

The IPO price on Thursday came in at the lower end of Uber’s targeted price range of $44 to $50 per share. The caution may have been driven by escalating doubts about the ability of ride-hailing services to make money since Uber’s main rival, Lyft, went public six weeks ago.

Jitters about an intensifying U.S. trade war with China have also contributed to the caution. Stocks opened broadly lower on Wall Street after the two countries failed to reach a deal before Friday’s tariff deadline.

Even at the tamped-down price, Uber now has a market value of $82 billion — five times more than Lyft’s.

Before the opening bell, Khosrowshahi tried to manage expectations for the first day of trading.

“Today is only one day. I want this day to go great, but it’s about what we build in the next three to five years,” he said in an interview with CNBC. “And I feel plenty of pressure to build over that time frame.”

Uber, Khosrowshahi said, is dealing with a potential $12 trillion market so “it makes sense to lean forward.”

He predicted that younger generations will not want to own cars. “I think more and more you’re going to have transportation on demand services, essentially de-bundle the car. They’re going to want to push a button and get the transportation they want.”

Austin Geidt, one of Uber’s first employees, rang the opening bell. She joined the company nine years ago and is now head of strategy for the Advanced Technologies Group, working on autonomous vehicles. Over the years, she helped to lead its expansion in hundreds of new cities and countries.

Both Uber co-founders Travis Kalanick and Garrett Camp were present at the exchange but absent from the podium during the bell ringing.

A black Uber logo was hanging over exchange floor and bright green Uber Eats trucks were parked outside. Men in black T-shirts and hats with the Uber Eats logo handed out drinks and snacks on the trading floor while photos of sedans, helicopters and Jump bikes were shown on screens above.

No matter how Uber’s stock swings Friday, the IPO has to be considered a triumph for the company most closely associated with an industry that has changed the way millions of people get around. That while also transforming the way millions of more people earn a living in the gig economy.

Uber’s IPO raised another $8.1 billion as the company it tries to fend off Lyft in the U.S. and help cover the cost of giving rides to passengers at unprofitable prices. The San Francisco company already has lost about $9 billion since its inception and acknowledges it could still be years before it turns a profit.

That sobering reality is one reason that Uber fell short of reaching the $120 billion market value that many observers believed its IPO might attain.

Another factor working against Uber is the cold shoulder investors have been giving Lyft’s stock after an initial run-up. Lyft’s shares closed Thursday 23% below its April IPO price of $72.

Uber “clearly learned from its `little brother’ Lyft, and the experience it has gone through,” Wedbush Securities analysts Ygal Arounian and Daniel Ives wrote late Thursday.

Despite all that, Uber’s IPO is the biggest since Chinese e-commerce giant Alibaba Group debuted with a value of $167.6 billion in 2014.

“For the market to give you the value, you’ve either got to have a lot of profits or potential for huge growth,” said Sam Abuelsamid, principal analyst at Navigant Research.

Uber boasts growth galore. Its revenue last year surged 42% to $11.3 billion while its cars completed 5.2 billion trips around the world either giving rides to 91 million passengers or delivering food.

Uber might be even more popular if not for a series of revelations about unsavory behavior that sullied its image and resulted in the ouster of Kalanick as CEO nearly two years ago.

The self-inflicted wounds included complaints about rampant internal sexual harassment, accusations that it stole self-driving car technology, and a cover-up of a computer break-in that stole personal information about its passengers. What’s more, some Uber drivers have been accused of assaulting passengers, and one of its self-driving test vehicles struck and killed a pedestrian in Arizona last year while a backup driver was behind the wheel.

Uber hired Khosrowshahi as CEO to replace Kalanick and clean up the mess, something that analysts say has been able to do to some extent, although Lyft seized upon the scandals to gain market share.

Kalanick remains on Uber’s board and while he kept a relatively low profile on Friday, he can still savor his newfound wealth. At $45 per share, his stake in Uber will be worth $5.3 billion. Hundreds, if not thousands, of other Uber employees are expected to become millionaires in the IPO.

Meanwhile, scores of Uber drivers say they have been mistreated by the company as they work long hours and wear out their cars picking up passengers as they struggle to make ends meet. On Wednesday, some of them participated in strikes across the United States to highlight their unhappiness ahead of Uber’s IPO but barely caused a ripple. A similar strike was organized ahead of Lyft’s IPO to the same effect.

In its latest attempt to make amends, Uber disclosed Thursday that it reached a settlement with tens of thousands of drivers who alleged they had been improperly classified as contractors. The company said the settlement covering most of the 60,000 drivers making claims will cost $146 million to $170 million.

Now, Uber will focus on winning over Wall Street.

Uber may be able to avoid Lyft’s post-IPO stock decline because it has a different story to tell than just the potential for growth in ride-hailing, says Alejandro Ortiz, principal analyst with SharesPost. Uber, he said, has plans to be more than a ride-hailing company by being all things transportation to users of its app, offering deliveries, scooters, bicycles and links to other modes of transportation including public mass transit systems.

“Whether or not that pitch will work kind of remains to be seen. It’s nearly impossible to tell now,” he said. “Obviously the risk to the company now is they have a lot more shareholders that they have to convince.”