Second US Monkeypox Death as Virus Linked to Brain Inflammation

A second U.S. death was linked to monkeypox on Tuesday as health authorities published a study describing how two previously healthy young men experienced inflammation of the brain and spinal cord as a result of the virus. 

There have been nearly 22,000 U.S. cases in the current global outbreak, which began in May, but new infections have been falling since mid-August as authorities have distributed hundreds of thousands of vaccine doses. 

The latest fatal case involved a severely immunocompromised resident of Los Angeles County who had been hospitalized, the local health department said without revealing further details. 

“Persons severely immunocompromised who suspect they have monkeypox are encouraged to seek medical care and treatment early and remain under the care of a provider during their illness,” the department said. 

The first U.S. death linked to the viral illness occurred in Texas and was announced on August 30, although authorities said that because the person was severely immunocompromised, they were investigating what role monkeypox had played. 

The current global outbreak is primarily affecting men who have sex with men. 

Historically, the virus has been spread via direct contact with lesions, body fluids and respiratory droplets, and sometimes through indirect contamination via surfaces such as shared bedding.  

But in this outbreak, there is preliminary evidence that sexual transmission may also play a role. 

Brain and spinal cord inflammation 

The U.S. Centers for Disease Control and Prevention, meanwhile, published a report about two unvaccinated men in their 30s who experienced brain and spinal cord inflammation after testing positive for the virus. 

The first, patient A, was a gay man in his 30s from Colorado whose symptoms began with fever chills and malaise and progressed to rashes on his face, scrotum and extremities, with swabs of lesions testing positive for the virus. 

He also developed lower extremity weakness and numbness, was unable to empty his bladder, experienced a persistent and painful erection, and was hospitalized. 

Magnetic resonance imaging (MRI) revealed brain and spinal cord inflammation. He was treated with the oral monkeypox antiviral tecovirimat as well as other drugs and began to improve at two weeks. 

He was released but continued to have left leg weakness and required an assistive walking device at a one-month follow-up. 

A second person, patient B, was a gay man in his 30s from Washington. His fever, rashes and muscle pain progressed to bowel and bladder incontinence and progressive flaccid weakness of both legs. 

Brain and spinal cord inflammation was confirmed on MRI, and he was intubated in an intensive care unit, where he was treated with intravenous tecovirimat as well a drug to reduce inflammation and, finally, blood plasma exchange. 

He remains in the hospital but can walk with the assistance of a device. 

The report said the underlying mechanism behind the two cases was unclear — it might have been a direct invasion of the central nervous system or an autoimmune response triggered by monkeypox infection elsewhere in the body. 

Despite Cost Overruns, Delays, NASA Hopes to Launch Artemis 1 Soon

NASA has so far been unable to launch its first Artemis mission, bringing added scrutiny to a program that is billions of dollars over budget and years behind schedule in returning humans to the moon. VOA’s Kane Farabaugh reports that despite scrubbed launches, the U.S. space agency hopes to get the Artemis program off the ground by the end of the year.

Whistleblower Tells Senators of Twitter Security Flaws

U.S. senators expressed empathy with Twitter’s former security chief during a hearing on Tuesday as he outlined serious concerns about the influential social media platform.

“It doesn’t matter who has keys if you don’t have any locks on the doors. And this kind of vulnerability is not in the abstract. It’s not far-fetched to say an employee in the company could take over the accounts of all of the senators in this room,” said Peiter “Mudge” Zatko in testimony before the Senate’s Judiciary Committee.

“Given the real harm to users and national security, I determined it was necessary to take on the personal and professional risk to myself and to my family of becoming a whistleblower.”

Zatko, appearing under subpoena, added he was not making the disclosures “out of spite or to harm Twitter.”

Zatko, who made a number of revelations previously in an 84-page complaint to the Securities and Exchange Commission and other U.S. government regulatory agencies, said that executive incentives compel Twitter executives to prioritize profits over security.

“There was a culture of not reporting bad results up, only reporting good results up,” Zatko told the senators.

Judiciary Committee Chairman Senator Dick Durbin, a Democrat, noted that according to Zatko, “the door to that vault is wide open and that vault contains a lot more information about you than you can imagine.”

Several senators, from both the Democratic and Republican parties, expressed concern that Twitter’s vulnerabilities could constitute a national security threat.

“This data is a gold mine of information that could be used against America’s interest. Twitter has a responsibility to ensure that the data is protected and doesn’t fall into the hands of foreign powers,” said Chuck Grassley, the ranking Republican senator on the committee.

“Your testimony today has legitimized what most of us feel is a process out of control, that the regulatory environment is insufficient to the task,” said Senator Lindsey Graham a Republican. “It’s time to up our game in this country.”

Graham said he is working with Senator Elizabeth Warren, a Democrat, to create a regulatory system that would have “teeth,” similar to what has been enacted in Europe.

“I’m not reaching any conclusions, but clearly what we’re doing right now is not working,” said Richard Blumenthal, a Democrat on the committee, who raised the possibility of creating a new government agency to regulate tech companies and protect consumers.

One senator, Mazie Hirono, a Democrat, appeared exasperated that Twitter has not been held to account even though it has paid a $150 million fine for violating a consent decree with the Federal Trade Commission on protecting users’ data.

“Do people need to go to prison?” she asked Zatko.

“I think holding people accountable is a good start,” he replied.

Zatko, a former high-profile computer hacker who became head of cybersecurity research at a Defense Department research and development agency known as DARPA and subsequently worked at Google before joining Twitter in 2020, also testified there were suspected foreign agents working inside Twitter — from China, India and Nigeria — and that there was no way to track their access to company databases, including those containing users’ personal information.

Zatko said when he raised his concern with another Twitter executive about a particular suspected foreign agent inside the company that person replied: “Well, since we already have one, what does it matter if we have more?”

Twitter’s hiring process is independent of any foreign influence and access to data is managed through measures including background checks, access controls, and monitoring and detection systems and processes, according to a Twitter company spokesman.

“Today’s hearing only confirms that Mr. Zatko’s allegations are riddled with inconsistencies and inaccuracies,” a Twitter company spokesperson, who declined to be publicly identified, responded to VOA and did not elaborate.

Twitter Chief Executive Officer Parag Agrawal declined to voluntarily appear before the committee on Tuesday. Durbin and Grassley told reporters they will discuss issuing a subpoena to compel the executive to appear.

Zatko “continues to believe that through this public disclosure process, real world harm for Twitter users may be avoided and our country’s national security better protected,” said his attorney, Alexis Ronickher, in a statement following the hearing.

Following Zatko’s testimony, Twitter announced that its shareholders have approved a $44 billion takeover offer from Tesla Chief Executive Officer Elon Musk. But since making the bid, the billionaire has terminated the agreement, accusing Twitter of misrepresenting the number of authentic users. Twitter has countersued, and the matter is scheduled to be heard in Delaware’s chancery court next month.

A judge in the state of Delaware ruled last week that Zatko’s claims can be included in Musk’s case against Twitter.

Despite Cost Overruns and Delays, NASA Hopes to Launch Artemis 1 This Year

Hoping to witness the launch of NASA’s Artemis 1 rocket to the moon is – so far – an exercise in frustration for Mark Franko. 

“I was hoping to feel the noise and the power and the sound – it would have been pretty interesting to see, I think,” Franko told VOA as he and his friends tried to watch a launch behind a local restaurant not far from Cape Canaveral. But fuel leaks and other issues have twice postponed the most powerful rocket system ever created from taking off.   

Despite the delays, Franko’s friend, Mary Jane Patterson, thinks NASA shouldn’t be in a hurry to make the next launch attempt.   

 

“I think that they should bring it back to the building and really check it out completely and then go again. I feel like it was too soon to go off after the first problem, and I think that, whether it was PR [public relations] or whatever, they were trying to push the envelope but at the same time they can’t. I don’t think you can be too cautious,” she said. 

“It’s the first time we’ve flown this rocket and this capsule,” noted astronaut Stan Love, who spoke with VOA ahead of the first unsuccessful launch attempt. “There are many, many things that can go wrong. This is a test flight. Don’t get your expectations too high.” 

But with hundreds of thousands of tourists gathering in Florida for each launch attempt, joining media from around the world assembled at Cape Canaveral, Love knows those expectations are high, at least partly because of the large price tag of the endeavor. 

The original cost for the S-L-S, or “Space Launch System,” which includes the rocket and boosters that propel the Orion capsule into space, has grown from $10 billion to $20 billion. Each successful launch will cost about $4.1 billion. NASA’s inspector general expects the overall Artemis program to reach $93 billion by the time the first astronauts return to the surface of the moon, targeted for 2025. 

That’s if NASA can get the first uncrewed mission off the ground this year. 

“We’ve got to make sure the vehicle is ready to go, we’ve got to make sure it’s safe for crew, and those things just take time,” said Doug Hurley, a retired NASA astronaut who flew on the first crewed mission of Space X’s Crew Dragon capsule to the International Space Station. He now works for Northrop Grumman, one of the contractors working on Artemis, and he is quick to respond to critics who say the current effort to return to the moon is behind schedule and over budget.   

 

“I’ve heard that my whole career. Every aircraft I’ve been involved with, every spacecraft I’ve been involved with. We heard that with Crew Dragon flying – it was six years from the time the contract was awarded to the time we flew. It takes time to build these complicated machines. But it’s worth it.” 

As NASA troubleshoots difficulties while carefully weighing the risks in launching Artemis, cost isn’t the only factor.   

“Mission success comes as we assess the flight after the fact,” said David Reynolds, a deputy program manager for NASA, who added that the future of spaceflight depends on the performance of this first uncrewed attempt to return to the moon. 

 

“As you tick off the different boxes, you buy down a certain amount of risk for the crewed flight. And so, once you have made that determination and we decide that it is safe enough to fly with crew, we will have considered it a mission success.” 

But Mark Franko, who had to return to Tempe, Arizona, before the next potential launch, wonders if the effort to see Artemis 1 in person was worth it. 

“If you watch it on TV it would probably be closer,” he told VOA. 

NASA is now looking at launch windows in late September and early October. 

 

‘Squid Game,’ ‘Succession,’ ‘Ted Lasso’ vie for Emmy Awards

Emmy Awards host Kenan Thompson and the ceremony’s producers are promising a feel-good event — a phrase not applicable to several of the top nominated shows.

The best drama contenders include the violently dystopian “Squid Game,” bleak workplace satire “Severance” and “Succession,” about a powerful and cutthroat family. Even comedy nominee “Ted Lasso,” the defending champ, took a storytelling dark turn.

But after several pandemic-constrained awards seasons, Monday’s 74th Primetime Emmy Awards (airing 8 p.m. EDT on NBC, streaming on Peacock) will be big and festive, executive producers Reginald Hudlin and Ian Stewart said.

They’re actually taking a page from last year’s scaled-down ceremony and its club-style table seating for nominees.

“They had a ball. They had a party. They celebrated themselves,” Stewart said, recalling a comment made by actor Sophia Bush at the evening’s end: “Oh, my God, I actually had fun at the Emmys.”

The tables will be back and again reserved for nominees and their “significants,” Stewart said, but there will be some 3,000 other guests seated traditionally in the temporarily reconfigured 7,000-seat Microsoft Theater in downtown Los Angeles.

“When the nominees are having a great time that translates on screen,” Hudlin said, citing the “passionate, touching” speeches delivered by winners.

Thompson, the veteran “Saturday Night Live” cast member taking his first turn as Emmys host, said he wants to enjoy the ceremony and make sure others do.

“This should be a night of appreciating artistry and creativity and removing the stress of it all out. I get it — it sucks to lose, and everybody’s picking outfits and trying to do the red carpet thing,” Thompson said. “But at the same time, it’s an awesome thing to be in the room on Emmys night, and I don’t want that to get lost in the stress.”

He doesn’t expect anything mirroring the Will Smith-Chris Rock confrontation that cast a shadow over the Oscars earlier this year, Thompson said.

Although HBO’s “Succession,” which won the best drama series award in 2020, and “Ted Lasso” from Apple TV+ are considered the front-runners for top series honors, there’s potential for surprises. Netflix’s “Squid Game,” a global sensation, would be the first non-English language drama series to win an Emmy.

On the comedy side, ABC’s acclaimed newcomer “Abbott Elementary” could become the first broadcast show to win the best comedy award since the network’s “Modern Family” in 2014. It’s also among the few contenders this year, along with “Squid Game,” to field a substantial number of nominees of color.

At the Emmy creative arts ceremonies held earlier this month, the mockumentary-style show about educators in an underfunded Philadelphia school, won the trophy for outstanding comedy series casting. “Succession” won the drama series casting award.

“The Crown,” last year’s big winner, wasn’t in the running this time because it sat out the Emmys eligibility period. The dramatized account of Queen Elizabeth II’s reign and family life will return for its fifth season in November, as Britain mourns the loss of its longest-serving monarch who died Thursday at age 96.

Twitter Whistleblower Bringing Security Warnings to Congress

Peiter “Mudge” Zatko, the Twitter whistleblower who is warning of security flaws, privacy threats and lax controls at the social platform, will take his case to Congress Tuesday. 

Senators who will hear Zatko’s testimony before the Senate Judiciary Committee are alarmed by his Twitter allegations at a time of heightened concern over the safety of powerful tech platforms. 

It’s Zatko’s second Capitol Hill appearance, and in some ways a 21st-century echo of his first. In 1998, he testified before a Senate panel along with fellow members of a hacker collective who warned about the security dangers of the then-emerging internet age. 

Zatko, a respected cybersecurity expert, was Twitter’s head of security until he was fired early this year. He brought the stunning allegations to Congress and federal regulators, asserting that the influential social platform misled regulators about its cyber defenses and efforts to control millions of “spam” or fake accounts. 

Sen. Dick Durbin, the Illinois Democrat who chairs the panel, has said that if Zatko’s claims are accurate, “they may show dangerous data privacy and security risks for Twitter users around the world.” 

Musk battle

Zatko’s accusations are also playing into billionaire tycoon Elon Musk’s battle with Twitter. The Tesla CEO is trying to get out of his $44 billion bid to buy the company; Twitter has sued to force him to complete the deal. The Delaware judge overseeing that case ruled last week that Musk can include new evidence related to Zatko’s allegations in the high-stakes trial set to start October 17. 

The allegation that Twitter engaged in deception in its handling of automated “spam bot” accounts is at the core of Musk’s attempt to back out of the Twitter deal. 

At the same time, many of Zatko’s claims are uncorroborated and appear to have little documentary support. In a statement, Twitter has called Zatko’s description of events “a false narrative.” 

Also Tuesday, Twitter’s shareholders are scheduled to vote on the company’s pending buyout by Musk. The vote is something of a formality given that the deal is on hold while the court case plays out. But if the measure passes as expected, it would pave the way for a Musk takeover should Twitter prevail in court. 

Zatko also filed complaints with the Justice Department, the Federal Trade Commission and the Securities and Exchange Commission. Among his most serious accusations is that Twitter violated the terms of a 2011 FTC settlement by falsely claiming that it had put stronger measures in place to protect the security and privacy of its users. 

The SEC is questioning Twitter about how it counts fake accounts on its platform. Twitter uses counts of its presumably real users to attract advertisers, whose payments make up about 90% of its revenue. The “spam bots” have no value to advertisers because there’s no person behind them. 

San Francisco-based Twitter has an estimated 238 million daily active users worldwide. The company says it removes 1 million spam accounts daily. 

‘Egregious deficiencies’

Zatko’s 84-page complaint alleges that he found “extreme, egregious deficiencies” on the platform, including issues with “user privacy, digital and physical security, and platform integrity/content moderation.” 

It accuses CEO Parag Agrawal and other senior executives and board members of making “false and misleading statements to users and the FTC” about these issues. Twitter denies those claims and has said that Zatko was fired in January for “ineffective leadership and poor performance.” Zatko’s attorneys say the performance claim is false. 

Twitter also hinted that Zatko’s complaint might be designed to bolster Musk’s legal fight with the company. Twitter called Zatko’s complaint “a false narrative” that is “riddled with inconsistencies and inaccuracies, and lacks important context.” 

News of Zatko’s complaint surfaced August 23, almost two months before the Twitter-Musk trial is scheduled to begin. One of Zatko’s attorneys has said “he’s never met Elon Musk. Doesn’t know Elon Musk. They know people in common.” 

The company also says it has significantly tightened security since 2020. 

Among Zatko’s specific allegations: 

— The company had such poor cybersecurity that it easily could have been exposed to outside attacks or attempts to siphon off its internal data. 

—The company lacked effective leadership, with its top executives practicing “deliberate ignorance” of pressing problems. Zatko described former CEO Jack Dorsey as “extremely disengaged” during the last months of his tenure, to the point where he wouldn’t even speak during meetings on complex issues. Dorsey stepped down in November 2021. 

—That Twitter knowingly allowed the government of India to place its agents on the company payroll, where they had “direct unsupervised access” to highly sensitive data on users. It makes a parallel but less detailed accusation that Twitter took funding from unidentified Chinese entities who may have gained access enabling them to access the identities and sensitive data of Chinese users who secretly use Twitter, which is officially banned in China. 

Better known by his hacker handle “Mudge,” Zatko, 51, first gained prominence in the 1990s. He was the best-known member of the Boston-based collective L0pht, which pioneered ethical hacking, embarrassing companies including Microsoft for poor security. His work raised awareness in the computing world that forced such major companies to take security seriously. He co-founded the consultancy @Stake, which was later acquired by Symantec. 

Zatko later worked in senior positions at the Pentagon’s Defense Advanced Research Projects Agency and Google. He joined Twitter at Dorsey’s urging in late 2020, the same year the company suffered an embarrassing security breach involving hackers who broke into the Twitter accounts of world leaders, celebrities and tech moguls, including Musk, attempting to scam their followers out of bitcoin. 

Biden Administration Plans to Boost US Biotechnology Manufacturing

In an executive order signed Monday, President Joe Biden announced steps by his administration to bolster the “bioeconomy” in the United States, a classification that covers research and development across a broad swath of products, including medical supplies, sustainable new fuels and food, as well as technologies meant to help fight climate change.

The order comes barely a month after Biden signed a major piece of legislation, the CHIPS Act, meant to supercharge U.S. manufacturing of semiconductors, an area in which the U.S. has lost its once-dominant global position.

The effort to boost the U.S. biotech sector further underscores the administration’s apparent belief that deeper engagement by the federal government with domestic manufacturing operations is necessary to preserve U.S. competitiveness in the global economy.

In a briefing over the weekend, administration officials made it clear that the administration’s push to bring more U.S.-based biotechnology manufacturing online comes as a response to other countries — particularly China — investing heavily in the sector.

Administration officials stressed that biotechnology-based products and “biomanufacturing” present a promising alternative to many current products — fuel, plastics and other materials — that are currently made using the byproducts of carbon-laden petrochemicals.

Order text

The executive order reads, in part, “It is the policy of my Administration to coordinate a whole-of-government approach to advance biotechnology and biomanufacturing towards innovative solutions in health, climate change, energy, food security, agriculture, supply chain resilience, and national and economic security.”

It continues, “Central to this policy and its outcomes are principles of equity, ethics, safety, and security that enable access to technologies, processes, and products in a manner that benefits all Americans and the global community and that maintains United States technological leadership and economic competitiveness.”

Caution urged

Among the Biden administration’s promises in the executive order is a vow to “substitute fragile supply chains from abroad with strong chains at home.” But not everyone agrees that a government effort to manipulate the supply chain is the smartest strategy for the long run.

“Government can play a role in funding basic research, university labs and the rest, but when it starts micromanaging supply chains, you end up with more fragile supply chains than robust ones,” Scott Lincicome, a director for general economics and trade at the Libertarian-leaning Cato Institute, told VOA.

Similarly, he said, government decisions to privilege “onshore” production over foreign producers can be dangerous.

“There’s nothing wrong with domestic manufacturing, but as we’ve learned throughout the pandemic, there’s a big problem with putting all of your eggs in one basket, either all foreign or all domestic,” Lincicome said.

“While onshoring can insulate you from foreign shocks, it makes you far more vulnerable to domestic shocks,” he added. “And in the process, it makes you poorer and weaker overall. The best approach is to have a very open, diverse global supply chain with domestic networks, foreign suppliers, and a very light government touch on trade, investment, talent and the rest.”

Multiple aims

The executive order lays out a number of areas in which the Biden administration plans to flex the federal government’s muscle, including the domestic manufacturing of biotechnology products. The aim is to encourage both the creation of domestic manufacturing facilities, as well as the supply chains of fuel and raw materials needed to operate them.

The administration also promises to help create markets for biotechnology products by increasing mandatory purchasing requirements for federal agencies.

In addition, the executive order proposes to push more funding into research and development and to provide innovators support in the form of federal data that helps identify unmet needs. Other efforts will include job training programs, streamlined regulatory approval of new products, and cooperative programs with international partners.

Mending fences

The administration’s push to help U.S. biotechnology firms could go some way toward mending fences with the industry, which was angered by elements of the Inflation Reduction Act (IRA), which Biden recently signed into law.

The IRA, for the first time, allows Medicare, the government health insurance program for senior citizens, to bargain with pharmaceutical firms over the prices of some prescription drugs. Many in the industry strongly opposed the measure, claiming it would reduce incentives to innovate.

The executive order comes less than a week after the Biotechnology Innovation Organization sent a letter to the administration requesting it to “take additional steps to foster the development and deployment of pioneering technologies that will further reduce greenhouse gas emissions in manufacturing, transportation, and agricultural supply chains to build a stronger, more resilient, and environmentally sustainable economy.”

Biden signed the order before traveling to Boston, where he was scheduled to tout the results of the infrastructure bill he signed last year, which pumped federal money into a wide array of construction projects.

Also on Monday, Biden named Renee Wegrzyn, a biotechnology executive, to head the new Advanced Research Projects Agency for Health. The announcement came as part of a discussion of Biden’s “moonshot” initiative to drive new research on treatments for cancer.

Biden Hopes Ending Cancer Can Be ‘National Purpose’ for US

President Joe Biden on Monday urged Americans to come together for a new “national purpose” — his administration’s effort to end cancer “as we know it.”

At the John F. Kennedy Presidential Library and Museum, Biden channeled JFK’s famed moonshot speech 60 years ago, likening the space race to his own effort and hoping it, too, would galvanize Americans.

“He established a national purpose that could rally the American people and a common cause,” Biden said of Kennedy’s space effort, adding that “we can usher in the same unwillingness to postpone.”

Biden hopes to move the U.S. closer to the goal he set in February of cutting U.S. cancer fatalities by 50% over the next 25 years and to dramatically improve the lives of caregivers and those suffering from cancer. Experts say the objective is attainable — but with adequate investments.

The president called his goal of developing treatments and therapeutics for cancers “bold, ambitious, and I might add, completely doable.”

In his speech, Biden called on the private sector to make drugs more affordable and data more regularly available. He ticked off medical advancements possible with focused research, funding and data.

And he spoke of a new federally backed study that seeks evidence for using blood tests to screen against multiple cancers — a potential game-changer in diagnostic testing to dramatically improve early detection of cancers.

Danielle Carnival, the White House coordinator for the effort, told The Associated Press that the administration sees huge potential in the commencement of the blood diagnostic study on identifying cancers.

“One of the most promising technologies has been the development of blood tests that offer the promise of detecting multiple cancers in a single blood test and really imagining the impact that could have on our ability to detect cancer early and in a more equitable way,” Carnival said. “We think the best way to get us to the place where those are realized is to really test out the technologies we have today and see what works and what really has an impact on extending lives.”

In 2022, the American Cancer Society estimates, 1.9 million new cancer cases will be diagnosed and 609,360 people will die of cancer diseases. The Centers for Disease Control and Prevention rank cancer as the second-highest killer of people in the U.S. after heart disease.

The issue is personal to Biden, who lost his adult son Beau in 2015 to brain cancer. After Beau’s death, Congress passed the 21st Century Cures Act, which dedicated $1.8 billion over seven years for cancer research and was signed into law in 2016 by President Barack Obama.

Obama designated Biden, then vice president, to run “mission control” on directing the cancer funds as a recognition of Biden’s grief as a parent and desire to do something about it. Biden wrote in his memoir Promise Me, Dad that he chose not to run for president in 2016 primarily because of Beau’s death.

Despite Biden’s attempts to hark back to Kennedy and his space program, the current initiative lacks that same level of budgetary support. The Apollo program garnered massive public investment — more than $20 billion, or more than $220 billion in 2022 dollars adjusted for inflation. Biden’s effort is far more modest and reliant on private sector investment.

Still, he’s tried to maintain momentum for investments in public health research, including championing the Advanced Research Projects Agency for Health (ARPA-H), modeled after similar research and development initiatives benefiting the Pentagon and intelligence community.

On Monday, Biden announced Renee Wegrzyn as the inaugural director of ARPA-H, which has been given the task of studying treatments and potential cures for cancers, Alzheimer’s, diabetes and other diseases. He also announced a new National Cancer Institute scholars’ program to provide funding to early-career scientists studying treatments and cures for cancer, with a focus on underrepresented groups and those from diverse backgrounds.

The president was joined by Caroline Kennedy, the daughter of JFK who is now the U.S. ambassador to Australia. And he was expected to speak later in the day at a fundraiser for the Democratic National Committee.

Experts agree it’s far too early to say whether these new blood tests for finding cancer in healthy people will have any effect on cancer deaths. There have been no studies to show they reduce the risk of dying from cancer. Still, they say setting an ambitious goal is important.

Carnival said the National Cancer Institute study was designed so that any promising diagnostic results could be swiftly put into widespread practice while the longer-term study — expected to last up to a decade — progresses. She said the goal was to move closer to a future where cancers could be detected through routine bloodwork, potentially reducing the need for more invasive and burdensome procedures like colonoscopies, and therefore saving lives.

Scientists now understand that cancer is not a single disease, but hundreds of diseases that respond differently to different treatments. Some cancers have biomarkers that can be targeted by existing drugs that will slow a tumor’s growth. Many more targets await discovery.

“How do we learn what therapies are effective in which subtypes of disease? That to me is oceanic,” said Donald A. Berry, a biostatistician at the University of Texas M.D. Anderson Cancer Center. “The possibilities are enormous. The challenges are enormous.”

Despite the challenges, he’s optimistic about cutting the cancer death rate in half over the next 25 years.

“We can get to that 50% goal by slowing the disease sufficiently across the various cancers without curing anybody,” Berry said. “If I were to bet on whether we will achieve this 50% reduction, I would bet yes.”

Even without new breakthroughs, progress can be made by making care more equitable, said Dr. Crystal Denlinger, chief scientific officer for the National Comprehensive Cancer Network, a group of elite cancer centers.

And any effort to reduce the cancer death rate will need to focus on the biggest cancer killer, which is lung cancer. Mostly attributable to smoking, lung cancer now causes more cancer deaths than any other cancer. Of the 1,670 daily cancer deaths in the United States, more than 350 are from lung cancer.

Dr. Michael Hassett of the Dana-Farber Cancer Institute in Boston said Biden’s goal to reduce cancer deaths could be met by following two parallel paths: one of discovery and the other making sure as many people as possible are reaping the advantages of existing therapies and preventive approaches.

“If we can address both aspects, both challenges, major advances are possible,” Hassett said.

EU Regulator Backs Pfizer’s Omicron-Adapted Vaccine Booster

The European Medicines Agency (EMA) on Monday recommended a COVID-19 booster designed to combat the currently circulating Omicron BA.4/5 subvariants, days after endorsing a pair of boosters tailored to target the older BA.1 Omicron variant.

The latest recommendation is for a so-called bivalent vaccine developed by Pfizer PFE.N and BioNTech 22UAy.DE, which targets BA.4/5 as well as the strain of the virus that originally emerged in China in December 2019 targeted by earlier COVID vaccines.

The EMA recommendation is to authorize the retooled booster shots for people aged 12 and above who have received at least primary vaccination against COVID. The final go-ahead will be subject to European Commission approval, which is expected to come shortly.

If authorized, the BA.4/5-tailored booster will be available in days to all 27 EU member states, Pfizer said in a statement on Monday.

While existing coronavirus vaccines provide good protection against hospitalization and death, their effectiveness, particularly against infection, was reduced as the virus evolved.

Earlier this month, the EMA endorsed both Pfizer-BioNTech and Moderna’s MRNA.O vaccines updated for BA.1.

EU officials signaled in recent months they were open to initially using boosters targeting the older BA.1 variant, given those specifically targeting the newer, now dominant Omicron BA.4/5 offshoots are further behind in development.

In contrast, the U.S. Food and Drug Administration insisted it was only interested in vaccines targeting BA.4/5. Last week, Pfizer-BioNTech and Moderna secured U.S. authorization for those despite limited available clinical data.

Given BA.1’s earlier emergence, data from human trials testing those redesigned vaccines has been submitted to EU regulators. For the BA.4/5 adapted vaccines, regulatory submissions are largely based on lab and animal studies.

Using animal and lab data to solicit regulatory approval is done regularly for flu vaccines that are revamped each year to combat the latest circulating strains.

On Monday, the EMA said its backing of the Pfizer-BioNTech updated BA.4/5 shot relied partly on data from human clinical trials available on the companies’ BA.1-tailored vaccine.

A clinical trial testing the Pfizer-BioNTech BA.4/5 vaccine in humans was initiated in early September, and data should be available later this autumn. Meanwhile, human trial data on Moderna’s BA.4/5 shot is expected by later this month or early October.

EU officials have encouraged member states to roll out boosters of the established original vaccines and the bivalent shots — whatever is readily available — for the vulnerable and elderly following a rise in summer infections, as protection waned due to the domination of BA.4 and especially BA.5.

Uptake could be limited, as people have become less worried about the disease, thanks in large part to the success of the first generation of shots. Experts also worry that the public may be suffering from vaccine fatigue and less likely to seek the boosters, which could be a fourth or fifth COVID shot for some.

Bezos Rocket Fails During Liftoff, Only Experiments Aboard

Jeff Bezos’ rocket company suffered its first launch failure Monday. No one was aboard, only science experiments. 

The Blue Origin rocket veered off course over West Texas about a minute after liftoff. The capsule’s launch abort system immediately kicked in, lifting the craft off the top. Several minutes later, the capsule parachuted onto the remote desert floor. 

Blue Origin’s launch commentary went silent when the capsule catapulted off the rocket, later announcing: “It appears we’ve experienced an anomaly with today’s flight. This wasn’t planned.” 

The mishap occurred as the rocket was traveling nearly 700 mph (1,126 kph) at an altitude of about 28,000 feet (8,500 meters). There was no video shown of the rocket — only the capsule — after the failure occurred. The rocket usually lands upright on the desert floor and then is recycled for future flights; clearly, that did not happen this time. 

Launch commentator Erika Wagner said the capsule managed to escape successfully, with the webcast showing it reaching a maximum altitude of more than 37,000 feet (11,300 meters). Thirty-six experiments were on board, half sponsored by NASA. 

“Booster failure on today’s uncrewed flight. Escape system performed as designed,” the company tweeted later. 

No further details were provided. 

It was the 23rd flight for the New Shepard program, named after the first American in space, Mercury astronaut Alan Shepard. The same kind of rocket and capsule have been used to carry paying passengers on 10-minute rides to the edge of space. It was the ninth flight for this rocket. 

Its most recent passenger flight was just last month. Bezos was on the first New Shepard crew last summer. Altogether, Blue Origin has carried 31 people to the edge of space. The company’s headquarters is in Kent, Washington. 

 

Poll: Americans Give Health Care System Failing Mark

When Emmanuel Obeng-Dankwa is worried about making rent on his New York City apartment, he sometimes holds off on filling his blood pressure medication. 

“If there’s no money, I prefer to skip the medication to being homeless,” said Obeng-Dankwa, a 58-year-old security guard. 

He is among a majority of adults in the U.S. who say that health care is not handled well in the country, according to a new poll from The Associated Press-NORC Center for Public Affairs Research.

The poll reveals that public satisfaction with the U.S. health care system is remarkably low, with fewer than half of Americans saying it is generally handled well. Only 12% say it is handled extremely or very well. Americans have similar views about health care for older adults. 

Overall, the public gives even lower marks for how prescription drug costs, the quality of care at nursing homes and mental health care are being handled, with just 6% or less saying those health services are done very well in the country. 

“Navigating the American health care system is exceedingly frustrating,” said A. Mark Fendrick, the director of the University of Michigan Center for Value-Based Insurance Design. “The COVID pandemic has only made it worse.” 

More than two years after the pandemic’s start, health care worker burnout and staffing shortages are plaguing hospitals around the country. And Americans are still having trouble getting in-person medical care after health centers introduced restrictions as COVID-19 killed and sickened millions of people around the country, Fendrick said. 

In fact, the poll shows an overwhelming majority of Americans, nearly 8 in 10, say they are at least moderately concerned about getting access to quality health care when they need it.

Black and Hispanic adults in particular are resoundingly worried about health care access, with nearly 6 in 10 saying they are very or extremely concerned about getting good care. Fewer than half of white adults, 44%, expressed the same level of worry. 

Racial disparities have long troubled America’s health care system. They have been abundantly clear during the COVID-19 pandemic, with Black and Hispanic people dying disproportionately from the virus. Black and Hispanic men also make up a disproportionately high rate of recent monkeypox infections.

Fifty-three percent of women said they are extremely or very concerned about obtaining quality care, compared to 42% of men. 

While Americans are united in their dissatisfaction with the health care system, that agreement dissolves when it comes to solutions to fix it. 

About two-thirds of adults think it is the federal government’s responsibility to make sure all Americans have health care coverage, with adults ages 18 to 49 more likely than those over 50 to hold that view. The percentage of people who believe health care coverage is a government responsibility has risen in recent years, ticking up from 57% in 2019 and 62% in 2017. 

Still, there’s not consensus on how that coverage might be delivered. 

About 4 in 10 Americans say they support a single-payer health care system that would require Americans to get their health insurance from a government plan. More, 58%, say they favor a government health insurance plan that anyone can purchase. 

There also is broad support for policies that would help Americans pay for the costs of long-term care, including a government-administered insurance plan similar to Medicare, the federal government’s health insurance for people 65 or older.

Retired nurse Pennie Wright, of Camden, Tennessee, doesn’t like the idea of a government-run health care system. 

After switching to Medicare this year, she was surprised to walk out of her annual well-woman visit, once fully covered by her private insurance plan, with a $200 bill. 

She prefers the flexibility she had on her private insurance plan. 

“I feel like we have the best health care system in the world, we have a choice of where we want to go,” Wright said. 

A majority of Americans, roughly two-thirds, were happy to see the government step in to provide free COVID-19 testing, vaccines and treatment. Roughly 2 in 10 were neutral about the government’s response. 

The government’s funding for free COVID-19 tests dried up at the beginning of the month. And while the White House says the latest batch of recommended COVID-19 boosters will be free to anyone who wants one, it doesn’t have money on hand to buy any future rounds of booster shots for every American. 

Eighty percent say they support the federal government negotiating for lower drug prices. President Joe Biden this summer signed a landmark bill into law allowing Medicare to negotiate the price of prescription drugs. The move is expected to save taxpayers as much as $100 billion over the next decade. 

“Medication costs should be low, to the minimum so that everyone can afford it,” said Obeng-Dankwa, the Bronx renter who has trouble paying for his medication. “Those who are poor should be able to get all the necessary health they need, in the same way someone who also has the money to pay for it.”

Carlos Alcaraz Wins US Open for 1st Slam Title, Top Ranking

Carlos Alcaraz used his combination of moxie and maturity to beat Casper Ruud 6-4, 2-6, 7-6 (1), 6-3 in the U.S. Open final on Sunday to earn his first Grand Slam title at age 19 and become the youngest man to be ranked No. 1.

Alcaraz is a Spaniard who was appearing in his eighth major tournament and second at Flushing Meadows but already has attracted plenty of attention as someone considered the Next Big Thing in men’s tennis.

He was serenaded by choruses of “Olé, Olé, Olé! Carlos!” that reverberated off the closed roof at Arthur Ashe Stadium — and Alcaraz often motioned to the supportive spectators to get louder.

He only briefly showed signs of fatigue from having to get through three consecutive five-setters to reach the title match, something no one had done in New York in 30 years.

Alcaraz dropped the second set and faced a pair of set points while down 6-5 in the third. But he erased each of those point-from-the-set opportunities for Ruud with the sorts of quick-reflect, soft-hand volleys he repeatedly displayed.

And with help from a series of shanked shots by a tight-looking Ruud in the ensuing tiebreaker, Alcaraz surged to the end of that set.

One break in the fourth was all it took for Alcaraz to seal the victory in the only Grand Slam final between two players seeking both a first major championship and the top spot in the ATP’s computerized rankings, which date to 1973.

Ruud is a 23-year-old from Norway who is now 0-2 in Slam finals. He was the runner-up to Rafael Nadal at the French Open in June.

Ethereum Blockchain Set for ‘Monumental’ Overhaul

An army of computer programmers scattered across the globe is set to attempt one of the biggest software upgrades the crypto sector has ever seen this week to reduce its environmentally unfriendly energy consumption.

Developers have spent years working on a more energy-efficient version of the ethereum blockchain, a digital ledger that underpins a multibillion-dollar ecosystem of cryptocurrencies, digital tokens (NFTs), games and apps.

Ethereum — the second most important blockchain after bitcoin — burns through more power each year than New Zealand.

Experts say the changeover, expected to take place between Tuesday and Thursday, would slash energy consumption by more than 99%.

Enthusiasts hope a greener ethereum will spur wider adoption, particularly as a way of enabling banks to automate transactions and other processes.

But so far the technology has been used largely to create speculative financial products.

The ING bank said in a recent note that the switchover might help ethereum gain acceptability among policymakers and regulators.  

“This in turn may provide a boost to traditional financial institutions’ willingness to develop ethereum-based services,” the bank said.

The switchover, dubbed “the merge,” will change the way transactions are logged.

At the moment, so-called crypto miners use energy-guzzling rigs of computers to solve puzzles that reward them with new coins — a system known as “proof of work.”

The new system will get rid of those miners and their computer stacks overnight.

Instead, “validators” will have to put up 32 ether (worth about $55,000) — ethereum’s cryptocurrency — to participate in the new “proof of stake” system where they earn rewards for their work.

But the merge process will be risky.

Blockchain company Consensys called it a “monumental technological milestone” and the biggest update to ethereum since it was launched in 2015.

Critics have questioned whether such an upgrade will pass off without incident, given the sector’s history of instability.

Ethereum went offline in May for three hours when a new NFT project sparked a surge in buyers that overwhelmed the network.

Several exchanges and crypto companies said they would halt transactions during the merge process.

The upgrade also faces a possible rebellion from crypto mining companies whose business will be severely damaged.

They can try to hijack the process or create a “fork,” basically a smaller blockchain that would continue with the old mechanism.

And even if the “merge” is successful, ethereum will still face major hurdles before it can be more widely adopted.

For example, it is expensive to use and the update will not reduce fees.

And the wider crypto sector is beset by wildly fluctuating prices, security flaws and an array of scams.

Crypto lawyer Charles Kerrigan from the firm CMS told AFP that ethereum was “decentralized and complicated” and had not yet been tested enough for governments and banks to get onboard.

“There have been questions about how easily it could deal with upgrades of the type that traditional software vendors provide to customers,” he said. “A successful merge will answer those questions.”

Iraq Ancient Ruins Open Up to Tourism After IS Atrocities

Strolling along the ancient ruins of Hatra in Iraq’s north, dozens of visitors admired the site, where local initiatives seek to turn over a new leaf after a brief but brutal jihadist rule.

Designated an endangered world heritage site by UNESCO, Hatra dates back to the 2nd and 3rd centuries BC.

It is a two-hour drive from Mosul, the former “capital” proclaimed by the Islamic State (IS) group, which was recaptured in 2017 by Iraqi forces and an international coalition that backed them.

A tour of the site on Saturday, the first of its kind organized by a private museum in Mosul, aimed to boost tourism in the area.

Some 40 visitors, most of them Iraqis, were allowed to walk around the more than 2,000-year-old archaeological site in the golden hour of twilight.

The tourists took selfies in front of impressive colonnades and inspected the reliefs vandalized by IS jihadists.

“It has great history” allowing a peek into an ancient civilization, said Luna Batota, a 33-year-old on tour with her Belgian husband.

“A lot of history but at the same time a lot of unfortunate events took place here with IS,” she told AFP.

Batota works for a pharmaceutical company in Belgium, where she has lived since the age of nine.

Twenty-four years later, this is the first time she returns to her homeland.

Visiting Hatra stirred up “mixed feelings” for her, she said. “You see bullet holes, you see many empty bullets.”

An important religious and trading center under the Parthian empire, Hatra had imposing fortifications and magnificent temples, blending Greek and Roman architectural styles with oriental decorative elements.

In 2015, IS released a video showing its militants destroying a series of reliefs, firing at them and hacking away at a statue with a pickaxe.

In February, the authorities unveiled three restorations at the site: a Roman-style sculpture of a life-size figure and reliefs on the side of the great temple.

‘Not only war’ 

Five years after the defeat of IS, Mosul and its surroundings have regained a sense of normalcy, even as rehabilitation efforts suffer setbacks and many areas still bear the scars of the fight against the jihadists.

The tour of Hatra was organized by the Mosul Heritage House, a private museum inaugurated in June.

But even before it, the site drew individual visitors, according to one of the organizers, Fares Abdel Sattar, a 60-year-old engineer.

This new initiative seeks to “showcase the heritage and identity” of Mosul and its broader Nineveh province, he said.

After its rise to power in 2014 and the conquest of swathes of Iraq and Syria, IS faced counteroffensives in both countries. Iraqi forces finally claimed victory in late 2017.

As Iraq gradually opens up to foreign tourism, dozens of visitors — particularly from the West — are now exploring the country, with some even venturing into Mosul.

The Hatra group are pioneers, visiting at a time when the US, British and other governments are warning their citizens against travel to Iraq, citing the risks of terrorism, kidnapping, armed conflict and civil unrest.

The tourism sector also suffered a setback with the case of British pensioner James Fitton, who was detained and condemned to 15 years in jail over pottery shards he picked at an archaeological site, before a court in July overturned the sentence and he flew back home.

Religious tourism to the Shiite holy cities of Karbala and Najaf has been thriving, mostly from Iran.

However, challenges remain and tourist infrastructure is still basic in Iraq, a country rich in oil but ravaged by decades of fighting.

“Mosul isn’t only war, IS, terrorism,” said Beriar Bahaa al-Din, a doctoral student in anthropology at the University of Exeter in Britain, on the Hatra visit.

“Mosul is a civilization, heritage, culture,” he added.

“This impressive site should be full of tourists from across the globe.”

Spielberg Confronts His Childhood as ‘Fabelmans’ Premieres in Toronto

Steven Spielberg finally turned the camera on his own childhood — from his parents’ troubled marriage to anti-Semitic bullying — as his new movie “The Fabelmans” received its world premiere on a star-studded Saturday at the Toronto film festival.

Considered one of Hollywood’s greatest living directors, with classics from “Jaws” to “E.T.”, Spielberg told a rapturous audience how he had long wanted to make such a deeply personal movie, but had eventually been motivated by the “fear” of the pandemic.

“I don’t think anybody knew in March or April of 2020 what was going to be the state of the art, the state of life, even a year from then,” said Spielberg.

“I just felt that if I was going to leave anything behind, what was the thing that I really need to resolve and unpack about my mom and my dad and my sisters?” he said after the screening at North America’s biggest film festival.

“It wasn’t now or never, but it almost felt that way,” said the 75-year-old.

The movie — which will be released in November — is technically semi-autobiographical, following young Sammy Fabelman and his family, although the parallels to Spielberg’s own life could hardly be more clear.

Like the real Spielberg, the Fabelmans move from New Jersey to Arizona and eventually California, with Sammy falling in love with filmmaking and honing his craft as a young director with the help of willing friends and improvised camera tricks.

“It was really using glue and spit, trying to figure out how to put things together,” recalled Spielberg after the film, which recreates many of the amateur movies he made as a teenager.

“I made all the behind-the-scenes stuff in this movie much better than the actual 8mm films I shot… it was a great do-over!”

‘Outsider’

While directing and filmmaking are a source of comfort and escapism for young Sammy, the movie tackles head-on his problems at home, including within the marriage of his parents — played by Michelle Williams and Paul Dano.

Another sequence recalls anti-Semitic taunts by two bullies at his California high school — a real-life incident Spielberg said he wanted to include in the film, without placing it center stage.

“Bullying is only a small aspect of my life. Anti-semitism is an aspect of my life but it isn’t any kind of a governing force in my life,” he said.

“It made me very, very aware of being an outsider growing up.”

Before the screening, Spielberg noted that “The Fabelmans” is his first-ever film to be officially entered at a film festival, marking a coup for the Toronto event.

The Toronto International Film Festival (TIFF), renowned for its large cinephile crowds as well as A-list stars, was hit badly by the pandemic, but this year has seen the return of packed audiences and red carpets.

No ‘swan song’

Earlier on Saturday, Jennifer Lawrence drew screaming fans to the red carpet for “Causeway,” an indie drama in which she plays a wounded Army engineer struggling to recover from conflict-zone trauma back in her hometown of New Orleans.

Daniel Craig and the star-studded cast of “Glass Onion: A Knives Out Mystery” arrived in Toronto for the whodunit sequel’s premiere.

Director Rian Johnson and Craig’s gentleman sleuth Benoit Blanc return for a new case featuring Edward Norton’s shady billionaire and his wealthy friends on a private Greek island.

Kate Hudson, Dave Bautista, Janelle Monae and Leslie Odom Jr co-star in the second installment of a budding “Knives Out” franchise which has been taken over by Netflix.

“I’m gonna keep making these until Daniel blocks me on his phone,” joked Johnson after the premiere.

Similarly, Spielberg assured the Toronto audience that reports he could step away from Hollywood after finally making the “The Fabelmans” were wide off the mark.

“It is not because I have decided to retire and this is my swan song… don’t believe any of that!” he said.

TIFF runs until September 18.

Swiatek Defeats Jabeur to Clinch US Open Crown

World No. 1 Iga Swiatek defeated Tunisia’s Ons Jabeur to win her second Grand Slam title of the year with a straight sets victory in the U.S. Open final on Saturday.

Polish star Swiatek overcame a spirited second set from fifth seed Jabeur to win 6-2, 7-6 (7/5) in 1 hour, 52 minutes at Arthur Ashe Stadium.

The victory followed Swiatek’s win at the French Open in June, making the 21-year-old the first woman since 2016 to win two Grand Slams in a single season.

Swiatek’s 10th career title also extended her remarkable record in tournament finals.

She has now won her last 10 finals, without dropping a set.

Swiatek collapsed on the court in relief after a win that saw her earn $2.6 million in prize money.

“I’m really glad it’s not in cash,” she quipped as she was presented with her winner’s cheque for a tournament she entered with low expectations.

“For sure this tournament was really challenging because it’s New York — it’s so loud, it’s so crazy,” said Swiatek who was also French Open champion in 2020.

“So many temptations in the city, so many people I’ve met who are so inspiring — it’s really mind-blowing for me and I’m so proud I could handle it mentally.”

But the loss was another agonizing near-miss for Jabeur, who had been bidding to become the first woman from Africa to win a Grand Slam.

The 28-year-old from Tunis also lost in the final of Wimbledon in July.

“I really tried but Iga didn’t make it easy for me,” Jabeur said. “She deserved to win today. I don’t like her very much today but it’s OK.”

The 28-year-old said she is already drawing up a battle plan for 2023.

At the Australian Open, she will have no points to defend having missed the 2022 tournament before she suffered a shock first round exit at the French Open.

Despite being the Wimbledon runner-up, ranking points were stripped from the event by the WTA after the All England Club banned Russian and Belarusian players.

“Points-wise, I don’t have defending points in Australia, in French Open, in Wimbledon, which is good. It’s a good thing. I’m definitely going for the No. 1 spot,” she said.

“I still have the Masters (WTA Finals in Fort Worth). I will maybe show myself there and build more confidence to really get ready for the next season because I feel like I have a lot to show.”

Jabeur, a late bloomer on the tour having still been outside the top 30 at the end of 2020, believes history shows that time remains on her side when it comes to her Grand Slam future.

“But I’m not someone that’s going to give up. I am sure I’m going to be in the final again and I will try my best to win it,” she said. 

‘Come From Away’ Readies for 9/11 Anniversary by Giving Back

This Monday, the cast and crew of the Broadway musical “Come From Away” have an appointment, as usual, with an aircraft carrier. 

Every year to honor Sept. 11, they help box thousands of meals for food banks across the city and perform for the volunteers aboard the U.S.S. Intrepid. 

“9/11 was a worldwide event. It was a time when we all felt helpless, and it was a time when we all wanted to help. And I think those sentiments continue right now,” said David Hein, who with his wife, Irene Sankoff, wrote the book, music and lyrics to “Come From Away.” 

The musical is set in the small Newfoundland town of Gander, which opened its arms to some 7,000 airline passengers diverted there when the U.S. government shut down airspace during 9/11. 

In a matter of a few hours, the town was overwhelmed by 38 planeloads of travelers from dozens of countries and religions, yet locals went to work in their kitchens and cleaned up spare rooms to offer space and food to the newcomers. 

Bittersweet visit

This year’s visit to the Intrepid by the New York cast will be bittersweet; it’s the last time the show will send representatives from Broadway. The show closes Oct. 2 after a five-year run. 

But it’s fitting that one of its last acts will be giving. Few shows have left such a legacy of connecting with the community — concerts for cancer victims, fundraisers for farmers facing drought and even cast members handing out dollar bills to the needy in the New York subway. 

“It’s been incredible to see us be inspired by the Newfoundlanders and then have this story inspire other people to do even more good,” Hein says. “It’s humbling to see that Shakespeare quote in action: ‘How far that little candle throws his beams! So shines a good deed in a naughty world.’” 

Giving back from the beginning

Giving back was baked into the show since the first workshop at Sheridan College in Ontario, where a hat was passed to raise money for animal shelters overwhelmed with new kittens. A benefit concert planned for later this month at the Gander airport will do the same “because kittens never stop,” Hein says, laughing. 

Since its debut, the musical — under director Christopher Ashley, who won a Tony for his work — has not changed, but it has seemed to take on different issues, depending on real events swirling at the time. 

The show’s first preview at its pre-Broadway run at Seattle Rep — Nov. 13, 2015 — came just hours after 130 people were killed in a coordinated terrorist attack in Paris. Offstage, the creators wondered what to do. Should they say something? Change the show? 

“I think it was Chris Ashley who said, ‘I think we just put on the show. I think this show says look for the helpers. It says, remember there’s more of us trying to do good than there are people trying to do harm. It says so much just by telling the story.’” 

Broadway opening

When Ivanka Trump and Canadian Prime Minister Justin Trudeau saw it in 2017 on Broadway, the issue was immigration and walls. Trudeau got onstage and said he was pleased, “the world gets to see what it is to lean on each other and be there for each other through the darkest times.” 

The COVID-19 pandemic gave the musical a different color, a sense of entering a period of uncertainty and reinforcing the notion of a community coming together. It was no surprise to Sankoff and Hein that the show’s costume department immediately started sewing masks for front line workers. 

“At a time when people were actually out of work and terrified that their industry wasn’t going to come back, so many of our company were saying, ‘How can I also help?’” Sankoff says. 

While the terror attacks are ever-present in the musical, the focus is on the Canadian response. The words “World Trade Center” and “terrorist” are each uttered only once. The creators like to call it a “9/12 story.” 

“We really did not want to do a show that was about 9/11,” says Hein, who was with his wife in New York on that fateful day. “We wanted to do a show about Newfoundland and how they had responded because that gave us hope, contrasting what we had felt on that day.” ​

North American tour

The Broadway version may soon be gone, but the future is still bright for “Come From Away.” There’s a North American tour, a production in London and one touring Australia. A version in Finland opens this month, one recently opened in Holland, another in Argentina and one in Sweden. 

“What’s amazing is how universal this story is. You have to change elements of it within a language and within a culture. But the concept of welcoming strangers and a world coming together is something that people are, I think, really hungry for,” says Hein. 

He and his wife and their 9-year-old daughter will be spending the 9/11 anniversary in Gander, at one of several concerts and benefits planned to commemorate the 21st year after the attacks. 

“9/11 is a national day of service. But I think what we’ve also learned is that any day can be a day of service — at any moment,” says Hein. “Kindness is a daily practice and one that we can all use a reminder for each day.” 

Opioid Epidemic Documentary Wins Top Prize at Venice Festival

“All the Beauty and the Bloodshed,” Laura Poitras’s epic documentary about photographer Nan Goldin and her activism against the Sackler family and their art connections has been awarded the Golden Lion for best film at the 79th Venice International Film Festival. 

Poitras thanked the festival for recognizing that “documentary is cinema” at the ceremony Saturday evening in Venice. 

Runner up went to Alice Diop’s “Saint Omer,” the narrative debut from the documentarian about a young novelist observing the trial of a woman accused of infanticide. 

Cate Blanchett and Colin Farrell won the top acting prizes. Blanchett won for her performance as a renowned conductor in Todd Field’s “TÁR” and Farrell for playing a man who has broken up with by his longtime friend in Martin McDonagh’s “The Banshees of Inisherin.” 

“Thank you so much, it’s such an enormous honor,” Blanchett said, having just flown back to Venice from the Telluride Film Festival where the film also played. 

Her performance as a successful woman in the world of international music whose reputation comes under threat has gotten nearly universal acclaim. 

“I’m shocked to get this and thrilled,” Farrell said in a live video message. McDonagh was on site to collect the prize before he got one of his own for the screenplay. 

Luca Guadagnino won the Silver Lion award for best director for the cannibal romance “Bones and All” starring Timothée Chalamet and Taylor Russell, who also was recognized for her performance for best young actress. 

“I have a speech prepared because I’m nervous,” Russell said. “I’m grateful beyond belief to be standing here. So many of my heroes are in this room.” 

The jury also gave a special jury prize to “No Bears,” by imprisoned Iranian director Jafar Panâhi. The acclaimed director was in July ordered by Iran to serve six-year prison sentence from a decade ago that had never been enforced. The order came as the government seeks to silence criticism amid growing economic turmoil and political pressure. 

Julianne Moore led the jury that selected Saturday’s winner from a pool of 23 films that included many Oscar hopefuls. The Oscar-winner presided over a jury that included French director Audrey Diwan, whose film “Happening” won the Golden Lion last year, author Kazuo Ishiguro (“Never Let Me Go”), who has been judging from his hotel room after testing positive for COVID-19, and Iranian actor Leila Hatami (“A Separation”). Also on the main jury were Italian director Leonardo Di Costanzo (“The Inner Cage”) Argentinian filmmaker Mariano Cohn (“Official Competition”) and Rodrigo Sorogoyen (“The Candidate”). 

Premiering in competition at Venice has launched many successful Oscar campaigns in recent years, leading to nominations and even wins. Seven times in the last nine years the best director Oscar has gone to a film that world premiered at the festival, including Chloé Zhao, Alfonso Cuarón, Alejandro G. Iñarritu, twice, Guillermo del Toro and Damien Chazelle. It’s also debuted a handful future best picture winners like “Nomadland,” “The Shape of Water” and “Birdman.” 

The festival cemented several films, actors and directors, as strong awards contenders for the season to come. Brendan Fraser moved many to tears for his portrayal of Charlie, a reclusive English teacher who weighs 600 pounds and is attempting to mend things with his estranged, cruel daughter Ellie (Sadie Sink) in Darren Aronofsky’s “The Whale.” 

Small Nuclear Reactors Emerge as Energy Option, but Risks Loom

A global search for alternative sources to Russian energy in light of the war in Ukraine has refocused attention on smaller, easier-to-build nuclear power stations, which proponents say could provide a cheaper, more efficient alternative to older model mega-plants.

U.K.-based Rolls-Royce SMR says its small modular reactors, or SMRs, are much cheaper and quicker to get running than standard plants, delivering the kind of energy security that many nations are seeking. France already relies on nuclear power for a majority of its electricity, and Germany kept the option of reactivating two nuclear plants it will shut down at the end of the year as Russia cuts natural gas supplies.

While Rolls-Royce SMR and its competitors have signed deals with countries from Britain to Poland to start building the stations, they are many years away from operating and cannot solve the energy crisis now hitting Europe.

 

Nuclear power also poses risks, including disposing of highly radioactive waste and keeping that technology out of the hands of rogue countries or nefarious groups that may pursue a nuclear weapons program.

Those risks have been accentuated following the shelling around Europe’s largest nuclear power plant in Zaporizhzhia, Ukraine, which has raised fears of potential nuclear disaster.

In the wake of the war, however, “the reliance on gas imports and Russian energy sources has focused people’s minds on energy security,” Rolls-Royce SMR spokesman Dan Gould said.  

An SMR’s components can be built in a factory, moved to a site in tractor trailers and assembled there, making the technology more attractive to frugal buyers, he said.

“It’s like building Lego,” Gould said. “Building on a smaller scale reduces risks and makes it a more investible project.”  

SMRs are essentially pressurized water reactors identical to some 400 reactors worldwide. The key advantages are their size — about one-tenth as big as a standard reactor — the ease of construction and the price tag.

The estimated cost of a Rolls-Royce SMR is $2.5 billion to $3.2 billion, with an estimated construction time of 5 1/2 years. That’s two years faster than it took to build a standard nuclear plant between 2016 and 2021, according to International Atomic Energy Agency statistics. Some estimates put the cost of building a 1,100-megawatt nuclear plant at between $6 billion and $9 billion.  

Rolls-Royce aims to build its first stations in the U.K. within 5 1/2 years, Gould said. Similarly, Oklahoma-based NuScale Power signed agreements last year with two Polish companies — copper and silver producer KGHM and energy producer UNIMOT — to explore the possibility of building SMRs to power heavy industry. Poland wants to switch from polluting, coal-powered electricity generation.  

Rolls-Royce SMR said last month that it signed a deal with Dutch development company ULC-Energy to look into setting up SMRs in the Netherlands.  

Another partner is Turkey, where Russia is building the Akkuyu nuclear power plant on the southern coast. Environmentalists say the region is seismically active and could be a target for terrorists.

The introduction of “unproven” nuclear power technology in the form of SMRs doesn’t sit well with environmentalists, who argue that proliferation of small reactors will exacerbate the problem of how to dispose of highly radioactive nuclear waste.

“Unfortunately, Turkey is governed by an incompetent administration that has turned it into a ‘test bed’ for corporations,” said Koray Dogan Urbarli, a spokesman for Turkey’s Green Party.

“It is giving up the sovereignty of a certain region for at least 100 years for Russia to build a nuclear power plant. This incompetence and lobbying power make Turkey an easy target for SMRs,” said Koray, adding that his party eschews technology with an “uncertain future.”

Gould said one Rolls-Royce SMR would generate nuclear waste the size of a “tennis court piled 1-meter high” throughout the plant’s 60-year lifetime. He said initially, waste would be stored on site at the U.K. plants and would eventually be transferred to a long-term disposal site selected by the British government.

M.V. Ramana, professor of public policy and global affairs at the University of British Columbia, cites research suggesting there’s “no demonstrated way” to ensure nuclear waste stored in what authorities consider to be secure sites won’t escape in the future.

The constant heat generated by the waste could alter rock formations where it’s stored and allow water seepage, while future mining activities could compromise a nuclear waste site’s integrity, said Ramana, who specializes in international security and nuclear energy.

Skeptics also raise the risks of possibly exporting such technology in politically tumultuous regions. Gould said Rolls-Royce is “completely compliant” with U.K. and international requirements in exporting its SMR technology “only in territories that are signatories to the necessary international treaties for the peaceful use of nuclear power for energy generation.”

Ramana said, however, there’s no guarantee nations will follow the rules.  

“Any country acquiring nuclear reactors automatically enhances its capacity to make nuclear weapons,” he said, adding that every SMR could produce “around 10 bombs worth of plutonium each year.”  

Rolls-Royce SMR could opt to stop supplying fuel and other services to anyone flouting the rules, but “should any country choose to do so, it can simply tell the International Atomic Energy Agency to stop inspections, as Iran has done, for example,” Ramana said.

Although spent fuel normally undergoes chemical reprocessing to generate the kind of plutonium used in nuclear weapons, Ramana said such reprocessing technology is widely known and that a very sophisticated reprocessing plant isn’t required to produce the amount of plutonium needed for weapons.

Voice-Operated Smartphones Target Africa’s Illiterate

Voice-operated smartphones are aiming at a vast yet widely overlooked market in sub-Saharan Africa — the tens of millions of people who face huge challenges in life because they cannot read or write.

In Ivory Coast, a so-called “Superphone” using a vocal assistant that responds to commands in a local language is being pitched to the large segment of the population — as many as 40 percent — who are illiterate.

Developed and assembled locally, the phone is designed to make everyday tasks more accessible, from understanding a document and checking a bank balance to communicating with government agencies.

“I’ve just bought this phone for my parents back home in the village, who don’t know how to read or write,” said Floride Jogbe, a young woman who was impressed by adverts on social media.

She believed the 60,000 CFA francs ($92) she forked out was money well spent.

The smartphone uses an operating system called “Kone” that is unique to the Cerco company, and covers 17 languages spoken in Ivory Coast, including Baoule, Bete, and Dioula, as well as 50 other African languages.

Cerco hopes to expand this to 1,000 languages, reaching half of the continent’s population, thanks to help from a network of 3,000 volunteers.

The goal is to address the “frustration” illiterate people feel with technology that requires them to be able to read or write or spell effectively, said Cerco president Alain Capo-Chichi, a Benin national.

“Various institutions set down the priority of making people literate before making technology available to them,” he told AFP.

“Our way skips reading and writing and goes straight to integrating people into economic and social life.”

Of the 750 million adults around the world who cannot read or write, 27 percent live south of the Sahara, according to UN figures for 2016, the latest year for which data is available.

The continent also hosts nearly 2,000 languages, some of which are spoken by tens of millions of people and are used for inter-ethnic communication, while others are dialects with a small geographical spread.

Lack of numbers or economic clout often means these languages are overlooked by developers who have already devised vocal assistants for languages in bigger markets.

Twi and Kiswahili

Other companies investing in the voice-operation field in Africa include Mobobi, which has created a Twi language voice assistant in Ghana called Abena AI, while Mozilla is working on an assistant in Kiswahili, which has an estimated 100 million speakers in East Africa.

Telecommunications expert Jean-Marie Akepo questioned whether voice operation needed the platform of a dedicated mobile phone.

Existing technology “manages to satisfy people”, he said.

“With the voice message services offered by WhatsApp, for example, a large part of the problem has already been solved.”

Instead of a new phone, he recommended “software with local languages that could be installed on any smartphone”.

The Ivorian phone is being produced at the ICT and Biotechnology Village in Grand-Bassam, a free-trade zone located near the Ivorian capital.

It came about through close collaboration with the government. The company pays no taxes or customs duties and the assembly plant has benefited from a subsidy of more than two billion CFA francs.

In exchange, Cerco is to pay 3.5 percent of its income to the state and train around 1,200 young people each year.

The company says it has received 200,000 orders since launch on July 21.

Thanks to a partnership with French telecommunications giant Orange, the phone will be distributed in 200 shops across Ivory Coast.

New York to Ramp Up Polio Vaccinations After Virus Found in Wastewater 

New York Governor Kathy Hochul declared a disaster emergency Friday in a bid to accelerate efforts to vaccinate residents against polio after the virus was detected in wastewater samples taken in four counties. 

Hochul’s executive order followed the discovery of the virus last month in samples from Long Island’s Nassau County, bordering the New York City borough of Queens. Earlier this year the virus was found in samples from Rockland, Orange and Sullivan counties, all north of the city.  

In July, the first confirmed case of polio in the United States in nearly a decade turned up in an adult in Rockland County, according to the state health department. 

“On polio, we simply cannot roll the dice,” State Health Commissioner Mary Bassett said in a statement. “If you or your child are unvaccinated or not up to date with vaccinations, the risk of paralytic disease is real.” 

Polio can cause irreversible paralysis in some cases, but it can be prevented by a vaccine first made available in 1955. While there is no known cure, three injections of the vaccine provide nearly 100% immunity. 

People of all ages are under threat, though the virus primarily affects children age 3 and younger.  

Officials urged inoculations for unvaccinated adults and children as young as 2 months, and they advised that vaccinated people receive a lifetime booster dose. 

Hochul’s declaration authorizes paramedics, midwives and pharmacists to administer polio vaccinations, among other steps, to accelerate inoculation rates. The order also directs health care providers to update the state with data on immunizations. 

The state of emergency will stay in effect until October 9. Health officials set a goal of getting 90% of residents vaccinated. 

The state health department warned that people in New York City and Rockland, Orange, Sullivan and Nassau counties are at the highest risk.  

Orange County has the lowest vaccination rate of the counties of concern with less than 59% being immunized, according to the state health department.