GENEVA — United Nations aid agencies warn climate change is wreaking havoc throughout large parts of eastern and southern Africa, worsening the plight of millions of people struggling to survive conflict, poverty, hunger and disease.

Since mid-April, El Nino-related heavy rainfall has led to extreme weather events across East Africa, including flooding, landslides, violent winds and hail.

In Sudan

The U.N. refugee agency, UNHCR, reports climate-induced heavy rains and flooding have upended the lives of tens of thousands of people in war-torn Sudan this year, displacing, injuring and killing many.

The agency warns that heavy seasonal rains are creating further misery for thousands of displaced, including refugees in dire need of humanitarian aid.

UNHCR spokesperson Olga Sarrado told journalists in Geneva Friday that torrential rains and severe floods in the past two weeks are having a devastating effect on the lives of thousands of refugees and internally displaced, noting that more than 11,000 people in the eastern Kassala state are in desperate straits.

“They include many families who recently arrived after fleeing violence in Sennar state,” she said. “Some have been displaced three or four times already since the start of the conflict.

“They have lost their belongings, including food rations, and are facing significant challenges in accessing clean water and sanitation facilities, increasing the risk of waterborne diseases,” she said.

The International Organization for Migration reports that more than 10 million people have become displaced inside Sudan and 2 million have sought refuge in neighboring countries since mid-April 2023, when rival generals from Sudan’s Armed Forces and paramilitary Rapid Support Forces plunged Sudan into war.

The UNHCR reports Sudan continues to host about 1 million refugees and asylum seekers from other countries.

Sarrado said the UNHCR is prepositioning core relief items and shelter kits in the eastern and western parts of the country where more rainfall is expected. She added that flooding in the Darfur region is causing concern among aid agencies, as this will further limit their ability to reach thousands of destitute people.

“The humanitarian needs are reaching epic proportions in the region, as hundreds of thousands of civilians remain in harm’s way and famine has been recently confirmed in a displacement site, as you all know,” she said. “The conflict has already destroyed crops and disrupted livelihoods. The climate crisis is making those displaced even more vulnerable now.”

In Southern Africa

While the heavy rains continue to pound refugees and displaced communities in Sudan, the World Food Program reports that more than 27 million people across Southern Africa, devastated by an El-Nino-induced drought are going hungry.

“I have just returned from Zimbabwe and Lesotho, two of the worst-affected countries, where 50% and 34% of the countries’ respective populations are food insecure,” said Valerie Guarnieri, WFP assistant executive director, program operations.

Speaking from Rome, she said the drought sweeping across the region has decimated crops, causing food prices to spiral and triggering a hunger crisis at a time when their food stocks are at the lowest.

She noted that the onset of this year’s lean season, which is usually from October to March, has come early this year.

“People are facing an early and much deeper lean season,” she said, adding that the situation is likely to get worse, “given production shortfalls and dwindling supply.”

She said that 21 million children, 1 out of 3 in southern Africa, are stunted and 3.5 million children are struggling with acute malnutrition and require nutrition treatment.

“These numbers are not as stark as they are in other parts of the region. Countries that are facing famine — Sudan, for instance. However, we should not have these kind of numbers in Southern Africa,” she said.

“We know that to deal with stunting, to prevent wasting, we need to be ensuring that all children and all women of child-bearing age, in particular, have access to the nutrients that they require in order to grow and to thrive.”

To deal with this crisis, Guarnieri said WFP is scaling up its operation to provide emergency food and nutrition support to 5.9 million people in seven countries between now and March.

She said that WFP is facing a $320 million funding shortfall “that jeopardizes our ability to mount a response at the scale required.”

UNHCR’s Sarrado also expressed concern that her agency’s appeal for nearly $40 million to assist and protect 5.6 million refugees, returnees, internally displaced and local communities in Sudan and five countries of refuge “has so far received only $5 million in funds.”
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CAPE CANAVERAL, Florida — What should have been a quick trip to the International Space Station may turn into an eight-month stay for two NASA astronauts if they have to switch from Boeing to SpaceX for a ride home.

There’s lingering uncertainty over the safety of Boeing’s new Starliner capsule, NASA officials said Wednesday, and the space agency is split over the risk. As a result, chances are increasing that test pilots Butch Wilmore and Suni Williams may have to watch from the space station as their Starliner is cut loose to return to Earth empty.

If that happens, NASA will leave behind two of four astronauts from the next SpaceX taxi flight in late September, with the vacant seats set aside for Wilmore and Williams on the return trip in February. The pair expected to be gone just a week or two when they launched June 5 as Starliner’s first crew.

NASA is bringing in additional experts to analyze the thruster failures experienced by Starliner before it docked. At the same time, NASA is looking more closely at SpaceX as a backup.

At this point, “we could take either path,” said Ken Bowersox, NASA’s space operations mission chief.

During a recent meeting, “we heard from a lot of folks that had concern, and the decision was not clear,” he said. A final decision is expected by mid-August.

Boeing issued a brief statement following NASA’s news update, repeating its position that the capsule could still safely bring the astronauts home.

“We still believe in Starliner’s capability and its flight rationale,” the company said.

Boeing will need to modify the capsule’s software in case Starliner ends up returning without a crew.

No serious consideration was given to launching a separate SpaceX flight just to retrieve Wilmore and Williams, according to commercial crew program manager Steve Stich.

Tests on the ground have replicated the thrust problems, pointing to seals as one culprit. But it’s still not understood how or why those seals swell when overheated and then shrink back to the proper size, Stich noted. All but one of the Starliner’s five failed thrusters have since been reactivated in orbit.

These thrusters are essential for allowing Starliner to back away from the space station following undocking, and for keeping the capsule in the proper position for moving out of orbit.

At the same time, engineers are grappling over helium leaks in Starliner’s propulsion system, crucial for maneuvering. The first leak occurred before liftoff but was deemed isolated and stable. Then more cropped up in flight.

NASA hired Boeing and SpaceX to ferry astronauts to and from the space station after the shuttles retired in 2011. SpaceX flew its first crew in 2020. Boeing stumbled on its first test flight without a crew and then fell further behind after a repeat demo.

Officials repeated their desire for a backup taxi service on Wednesday, A situation like this one could happen again, and “that’s why we want multiple vehicles,” Bowersox said.

The next crew flight will be SpaceX’s 10th for NASA. On Tuesday, it was delayed for a month until late September to allow for extra time to figure out how best to handle Starliner’s return. Three NASA astronauts and one Russian are assigned to the flight, and managers on Wednesday declined to say who might be bumped.
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GENEVA — Soaring temperatures in July have had detrimental effects on the well-being of hundreds of millions of people worldwide who have found the monthlong extreme heat too hot to handle, according to the World Meteorological Organization.

“The extreme heat, which continued throughout July after a hot June … has had really, really devastating impacts on communities, on people’s health, on ecosystems, also on economies,” WMO spokesperson Clare Nullis told journalists Tuesday in Geneva.

“Extreme heat has a domino effect across society,” she said, noting that the world’s hottest day on recent record was registered on July 22. “All of this is really yet another unwelcome indication, one of many, of the extent that greenhouse gases from human activities are, in fact, changing our climate.”

WMO data show widespread, intense and extended heat waves have hit every continent in the past year and global average temperatures have set new monthly records for 13 consecutive months from June 2023 to June 2024.

“At least 10 countries in the past year have recorded daily temperatures of more than 50 degrees Celsius [122 degrees Fahrenheit] in more than one location,” Nullis said. “You can well imagine this is too hot for the body to handle.”

WMO reports that Death Valley in California, considered to be the hottest place on Earth, registered an average monthly temperature of 42.5 degrees Celsius (108.5 degree Fahrenheit) at Furnace Creek, “which is a record for the site and possibly the world.”

WMO normally does not measure monthly temperature records. But Randall Cerveny, chief rapporteur for the WMO’s committee for evaluating climate and weather extremes, said ”the record appeared to be reasonable and legitimate.”

While human-induced activity is largely responsible for the long-term warming trend, meteorologists cite above-average temperatures over large parts of Antarctica as another contributing factor.

According to the European Union’s Copernicus Climate Change Service, this has resulted in anomalies of more than 10-degrees Celsius above average in some areas, and above-average temperatures in parts of the Southern Ocean.

WMO climate expert Alvaro Silva said two consecutive heat waves that hit Antarctica over the last two years have contributed to record global temperatures.

“The reason is still under research, but it seems to be related with the daily sea ice extent,” he said, noting the Antarctic daily sea ice extent in June 2024 “was the second lowest on record. … This follows the lowest extent that we have in Antarctica in terms of sea ice in 2023.”

Sea ice extent is the surface area of ice covering an ocean at a given time.

Speaking from the Portuguese capital, Lisbon, Silva provided a sobering regional overview of the heat waves and extreme heat events, which are contributing to record global temperatures.

He observed that July was the warmest on record in Asia, while in Africa, he cited record-breaking temperatures in Morocco as having had “an important impact in terms of human health and deaths.”

He said intense heat waves in southern and southeastern Europe have “caused casualties and severe impacts on health.” At the same time, he pointed out that the fallout of heat waves in North America have been quite severe, noting that on August 1, “more than 160 million people, about half of the United States population, were under heat alert.”

WMO officials say evidence of our rapidly warming planet underscores the urgency of the Call to Action on Extreme Heat initiative launched by United Nations Secretary-General Antonio Guterres July 25.

In issuing this call, the U.N. chief warned that “Earth is becoming hotter and more dangerous for everyone, everywhere” and this was posing an increased threat to “our socio-economic and environmental well-being.”

WMO officials also stressed the importance of adaptation to climate change as a lifesaving measure, noting that recent estimates produced by WMO and the World Health Organization indicate the global scale-up of heat-health-warning systems for 57 countries alone “has the potential to save an estimated 98,000 lives per year.”

WMO Secretary-General Celeste Saulo said bolstering heat early warning systems in line with her agency’s Early Warnings for All Initiative would ensure at-risk populations receive timely alerts so they can take “protective actions.”

But, she emphasized, climate adaptation alone is not enough.

“We need to tackle the root cause and urgently reduce greenhouse gas levels, which remain at record observed levels.”
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WASHINGTON — Ocean temperatures in the Great Barrier Reef hit their highest level in 400 years over the past decade, according to researchers who warned that the reef likely won’t survive if planetary warming isn’t stopped.

During that time, between 2016 and 2024, the Great Barrier Reef, the world’s largest coral reef ecosystem and one of the most biodiverse, suffered mass coral bleaching events. That’s when water temperatures get too hot and coral expel the algae that provide them with color and food, and sometimes die. Earlier this year, aerial surveys of over 300 reefs in the system off Australia’s northeast coast found bleaching in shallow water areas spanning two-thirds of the reef, according to Great Barrier Reef Marine Park Authority.

Researchers from Melbourne University and other universities in Australia, in a paper published Wednesday in the journal Nature, were able to compare recent ocean temperatures to historical ones by using coral skeleton samples from the Coral Sea to reconstruct sea surface temperature data from 1618 to 1995. They coupled that with sea surface temperature data from 1900 to 2024.

They observed largely stable temperatures before 1900 and steady warming from January to March from 1960 to 2024. And during five years of coral bleaching in the past decade — during 2016, 2017, 2020, 2022 and 2024 — temperatures in January and March were significantly higher than anything dating back to 1618, researchers found. They used climate models to attribute the warming rate after 1900 to human-caused climate change. The only other year nearly as warm as the mass bleaching years of the past decade was 2004.

“The reef is in danger, and if we don’t divert from our current course, our generation will likely witness the demise of one of those great natural wonders,” said Benjamin Henley, the study’s lead author and a lecturer of sustainable urban management at the University of Melbourne. “If you put all of the evidence together … heat extremes are occurring too often for those corals to effectively adapt and evolve.”

Across the world, reefs are key to seafood production and tourism. Scientists have long said additional loss of coral is likely to be a casualty of future warming as the world approaches the 1.5 degrees Celsius (2.7 degrees Fahrenheit) threshold that countries agreed to try and keep warming under in the 2015 Paris climate agreement.

Even if global warming is kept under the Paris Agreement’s goal, which scientists say Earth is almost guaranteed to cross, 70% to 90% of corals across the globe could be threatened, the study’s authors said. As a result, future coral reefs would likely have less diversity in coral species — which has already been happening as the oceans have grown hotter.

Coral reefs have been evolving over the past quarter century in response to bleaching events like the ones the study’s authors highlighted, said Michael McPhaden, a senior climate scientist at the National Oceanic and Atmospheric Administration who was not involved with the study. But even the most robust coral may soon not be able to withstand the elevated temperatures expected under a warming climate with “the relentless rise in greenhouse gas concentrations in the atmosphere,” he said.

The Great Barrier Reef serves as an economic resource for the region and protects against severe tropical storms.

As more heat-tolerant coral replaces the less heat-tolerant species in the colorful underwater rainbow jungle, McPhaden said there’s “real concern” about the expected extreme loss in the number of species and reduction in area that the world’s largest reef covers.

“It’s the canary in the coal mine in terms of climate change,” McPhaden said.
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Geneva — World Health Organization chief Tedros Adhanom Ghebreyesus on Wednesday called an “emergency” meeting of international experts amidst growing worries over the mpox virus.

With mpox spreading outside of the Democratic Republic of Congo, Tedros said the WHO emergency committee would meet “as soon as possible” to advise him on “whether the outbreak represents a public health emergency of international concern.”

A public health emergency of international concern is the highest alarm the WHO can sound and allows Tedros to trigger emergency responses under the International Health Regulations.

Formerly known as monkeypox, mpox is an infectious disease caused by a virus transmitted to humans by infected animals that can also be passed from human to human through close physical contact.

It was first discovered in humans in 1970 in DR Congo, causing fever, muscular aches and large boil-like skin lesions.

In May 2022, mpox infections surged worldwide, mostly affecting gay and bisexual men, due to the Clade IIb subclade.

The outbreak led the WHO to declare an international public health emergency (PHEIC), which lasted from July 2022 to May 2023. That outbreak has now largely subsided.

Since September 2023, a different strain of mpox, the Clade Ib subclade, has been surging in DR Congo.

On July 11, Tedros said more than 11,000 cases and 445 deaths had been reported in the giant African state this year, with children the most affected. The disease has since spread to neighboring countries.

A PHEIC has only been declared seven times since 2009: over H1N1 swine flu, poliovirus, Ebola, Zika virus, Ebola again, Covid-19 and mpox. 
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China’s Confucius Institutes teach Chinese around the world, but there’s more to them than that. VOA’s Kate Bartlett visited a new one that is hundreds of kilometers outside the capital in rural South Africa that’s also focusing on green technology. Camera: Zaheer Cassim.
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TOKYO — More than 120 people died of heatstroke in the Tokyo metropolitan area in July, when the nation’s average temperature hit record highs and heat warnings were in effect much of the month, Japanese authorities said Tuesday. 

According to the Tokyo Medical Examiner’s Office, many of the 123 people who died were elderly. All but two were found dead indoors, and most were not using air conditioners despite having them installed. 

Japanese health authorities and weather forecasters repeatedly advised people to stay indoors, consume ample liquids to avoid dehydration, and use air conditioning, because elderly people often think that air conditioning is not good for one’s health and tend to avoid using it. 

It was the largest number of heatstroke deaths in Tokyo’s 23 metropolitan districts in July since 127 deaths were recorded during a 2018 heatwave, the medical examiner’s office said. 

More than 37,000 people were treated at hospitals for heatstroke across Japan from July 1 to July 28, according to the Fire and Disaster Management Agency. 

The average temperature in July was 2.16 degrees Celsius (3.89 degrees Fahrenheit) higher than the average over the past 30 years, making it the hottest July since the Japan Meteorological Agency began keeping records in 1898. 

On Tuesday, heatstroke warnings were in place in much of Tokyo and western Japan. The temperature rose to about 34 C (93 F) in downtown Tokyo, where many people carried parasols or handheld fans. 

“I feel every year the hot period is getting longer,” said Hidehiro Takano from Kyoto. “I have the aircon on all the time, including while I’m sleeping. I try not to go outside.” 

Maxime Picavet, a French tourist, showed a portable fan he bought in Tokyo. “It works very, very well,” he said. “With this temperature, it’s a necessity.” 

The meteorological agency predicted more heat in August, with temperatures of 35 C (95 F) or higher. 

“Please pay attention to temperature forecasts and heatstroke alerts and take adequate precautions to prevent heatstroke,” it said in a statement. 
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Geneva — The World Health Organization is warning that governments throughout the world are unprepared to combat the global surge of COVID-19, which is putting millions of people at risk of severe disease and death.

“COVID-19 is still very much with us,” Dr. Maria Van Kerkhove, WHO director for epidemic and pandemic preparedness and prevention, told journalists in Geneva Tuesday.

“The virus is circulating in all countries. Data from our sentinel-based surveillance system across 84 countries reports that the percent of positive tests for SARS-CoV-2 has been rising for several weeks,” she said.

Not only is COVID-19 surging in many countries across seasons, she said, but at least 40 Olympic athletes have tested positive in Paris despite efforts by authorities to safeguard the venues against infectious disease circulation.

WHO chief Tedros Adhanom Ghebreyesus declared an end to the COVID-19 pandemic as an international health threat on May 5, 2023. Since then, the U.N. agency has received scant official information from countries regarding the number of new infections and deaths, as well as other essential information.

That has forced health agency officials to scroll through government websites, looking at ministry of health reports to ascertain monthly trends on hospitalizations linked to COVID-19 infections.

“On the hospitalization rates, we have seen increases in the Americas. We have seen increases in Europe. In recent months, we have seen increases in the Western Pacific,” Van Kerkhove said. “Thirty-five countries out of 234 countries and territories are providing this information. … So about 15% of available countries and territories have that information to share with us.”

Based on wastewater surveillance, WHO officials have determined that circulation of SARS-CoV-2, the virus that causes COVID-19, is 2 to 20 times higher than is currently being reported.

“This is significant because the virus continues to evolve and change, which puts us all at risk of a potentially more severe virus that could evade our detection and/or our medical interventions, including vaccinations,” said Van Kerkhove.

Over the last two years, she noted that there has been “an alarming decline in vaccine coverage,” especially among health workers and people over 60, “two of the most at-risk groups.”

“I am concerned,” said Van Kerkhove. “With such low coverage, with such large circulation, if we were to have a variant that was more severe, then the susceptibility of the at-risk populations to develop severe disease is huge. It is huge in every country.”

WHO officials observe that governments and their people have been lulled into a sense of complacency because the impact of COVID-19 is less now than it was during the pandemic. However, they also warn that could change for the worse as the immunity achieved through previous infections, and the protection achieved through vaccination, wears off.

The WHO says countries could and should be doing much more to prevent the current global surge from turning into another full-blown pandemic. The global health agency is urging countries to continue to sharpen their pandemic preparedness, readiness and response systems “to be ready for surges of COVID-19 as well as other emerging and reemerging pathogens,” such as avian influenza H5N1, mpox and dengue.

The WHO recommends that people in the highest risk groups receive a COVID-19 vaccine within 12 months of their last dose. To increase uptake and protection, it recommends people get their COVID-19 shot in tandem with their seasonal flu shot.

“Vaccination with any of the approved vaccines will protect against severe disease and death,” said Van Kerkhove. “It will lower your risk of developing severe disease. It will also lower your risk of developing post-COVID condition,” otherwise known as long COVID.
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WASHINGTON/SYDNEY — The United States and Australia kicked off high-level talks Tuesday that will focus on China’s “coercive behavior,” as well as the AUKUS nuclear submarine project, mounting tensions in the Middle East and climate change, officials said.

The annual Australia-U.S. AUSMIN talks, taking place in Annapolis, Maryland, include the top defense and diplomatic officials from both nations.

“We’re working together today to tackle shared security challenges, from coercive behavior by the PRC [People’s Republic of China], to Russia’s war of choice against Ukraine, to the turmoil in the Middle East,” U.S. Defense Secretary Lloyd Austin said.

“And I know that [this] year’s AUSMIN will deliver results for both of our peoples.”

The U.S. and China are at odds on a range of issues, including U.S. support for Taiwan. Another topic will be Chinese military activity in the South China Sea. China claims control over most of the sea, including the disputed Second Thomas Shoal, where U.S. ally the Philippines has maritime claims.

Austin spoke in the wake of a rocket strike on Monday in Iraq that wounded seven U.S. personnel, as the Middle East braced for a possible new wave of attacks by Iran and its allies following last week’s killing of senior leaders of militant groups Hamas and Hezbollah.

Australian Foreign Minister Penny Wong and Defense Minister Richard Marles held meetings in Washington on Monday, a day before the AUSMIN talks.

Marles highlighted the expanding role of a U.S. Marine rotational force in northern Australia and defense industry cooperation.

“We’re seeing America’s force posture in Australia grow really significantly. AUKUS is part of that, but it’s not the only part of that,” Marles said in talks with Austin, according to a statement.

Under the AUKUS program, Washington will sell three nuclear-powered submarines to Australia in the next decade. Wong said there was bipartisan U.S. political support for the program.

U.S. Ambassador to Australia Caroline Kennedy told ABC Television that China and climate change — priorities for the Pacific Islands, where the U.S. and Australia are competing with China for security ties — would be discussed.

“Obviously with China being such an important … trading partner and competitor for both of us, that is obviously one of the main topics,” she said.

“We are also talking about what we can do together to fight climate change [and] to help the Pacific Islands to build critical infrastructure to connect them,” she said.

As part of cooperating on environmental and resource issues, Australia will spend $200 million ($130 million U.S.) to upgrade ground station facilities in its remote central desert to process data from NASA’s Landsat Next satellite.

Landsat Next is an earth observation program the U.S. space agency says will provide early warnings on the onset of fires or ice melting. The program is scheduled to be launched in 2030.

U.S. Secretary of State Antony Blinken said the satellite data would also be used to target resource exploration in Australia, as the two nations develop a supply chain for critical minerals.

The U.S. and its allies are seeking to reduce China’s market dominance in rare earths and critical minerals used in electric vehicles and defense technology.
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washington — Twenty years ago on an Indonesian island, scientists discovered fossils of an early human species that stood at about 1.07 meters tall — earning them the nickname “hobbits.”

Now a new study suggests ancestors of the hobbits were even slightly shorter.

“We did not expect that we would find smaller individuals from such an old site,” study co-author Yousuke Kaifu of the University of Tokyo said in an email.

The original hobbit fossils date back to between 60,000 and 100,000 years ago. The new fossils were excavated at a site called Mata Menge, about 27 kilometers from the cave where the first hobbit remains were uncovered.

In 2016, researchers suspected the earlier relatives could be shorter than the hobbits after studying a jawbone and teeth collected from the new site. Further analysis of a tiny arm bone fragment and teeth suggests the ancestors were a mere 6 centimeters shorter and existed 700,000 years ago.

“They’ve convincingly shown that these were very small individuals,” said Dean Falk, an evolutionary anthropologist at Florida State University who was not involved with the research.

The findings were published Tuesday in the journal Nature Communications.

Researchers have debated how the hobbits – named Homo floresiensis after the remote Indonesian island of Flores – evolved to be so small and where they fall in the human evolutionary story. They’re thought to be among the last early human species to go extinct.

Scientists don’t yet know whether the hobbits shrank from an earlier, taller human species called Homo erectus that lived in the area, or from an even more primitive human predecessor. More research – and fossils – are needed to pin down the hobbits’ place in human evolution, said Matt Tocheri, an anthropologist at Canada’s Lakehead University.

“This question remains unanswered and will continue to be a focus of research for some time to come,” Tocheri, who was not involved with the research, said in an email.
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Abortion is restricted in Kenya, but in Kilifi County on the southern coast many women and girls with unplanned pregnancies say they have no choice but to undergo dangerous abortions without the intervention of a nurse or doctor. Local activists say the practice is contributing to high maternal mortality in the region. Halima Gongo reports.
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A community of breastfeeding women in Uganda is helping mothers who are struggling not to just feed their newborn babies, but to keep them alive. Halima Athumani and Mukasa Francis report from Uganda’s capital Kampala.
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BANGUI, Central African Republic — African health officials said mpox cases have spiked by 160% so far this year, warning the risk of further spread is high given the lack of effective treatments or vaccines on the continent.

The Africa Centers for Disease Control and Prevention said in a report released Wednesday that mpox, also known as monkeypox, has now been detected in 10 African countries this year including Congo, which has more than 96% of all cases and deaths.

Officials said nearly 70% of cases in Congo are in children younger than 15, who also accounted for 85% of deaths.

There have been an estimated 14,250 cases so far this year, nearly as many as all of last year. Compared to the first seven months of 2023, the Africa CDC said cases are up 160% and deaths are up 19%, to 456.

Burundi and Rwanda both reported the virus for the first time this week.

New outbreaks were also declared this week in Kenya and Central African Republic, with cases extending to its densely populated capital, Bangui.

“We are very concerned about the cases of monkeypox, which is ravaging (the capital region),” the Central African Republic’s public health minister, Pierre Somsé, said Monday.

On Wednesday, Kenya’s Health Ministry said it found mpox in a passenger traveling from Uganda to Rwanda at a border crossing in southern Kenya. In a statement, the ministry said that a single mpox case was enough to warrant an outbreak declaration.

The Africa CDC said the mpox death rate this year, at about 3%, “has been much higher on the African continent compared to the rest of the world.” During the global mpox emergency in 2022, fewer than 1% of people infected with the virus died.

Earlier this year, scientists reported the emergence of a new form of the deadlier version of mpox, which can kill up 10% of people, in a Congolese mining town that they feared might spread more easily among people. Mpox spreads via close contact with infected people, including via sex.

An analysis of patients hospitalized from October to January in eastern Congo suggested that recent genetic mutations in the virus were the result of the ongoing spread in people.

Unlike in previous mpox outbreaks, where lesions were mostly seen on the chest, hands and feet, the new form of mpox causes milder symptoms and lesions mostly on the genitals, making it harder to spot.

The medical charity Doctors Without Borders called the expanding mpox outbreak “worrying,” noting the disease had also been seen in camps for displaced people in Congo’s North Kivu region, which shares a border with Rwanda.

“There is a real risk of explosion, given the huge population movements in and out,” said Dr. Louis Massing, the group’s medical director for Congo.

Mpox outbreaks in the West have mostly been shut down with the help of vaccines and treatments, but barely any have been available in African countries including Congo.

“We can only plead … for vaccines to arrive in the country and as quickly as possible so that we can protect the populations in the areas most affected,” Massing said in a statement.

In May, WHO said that despite the ongoing outbreak in Africa and the potential for the disease to spread internationally, not a single donor dollar had been invested in containing mpox.

Earlier this week, the Coalition for Epidemic Preparedness Innovations announced it was starting a study in Congo and other African countries next month to see if giving people an mpox shot after they had been exposed to the disease could help prevent severe illness and death.
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PHOENIX, ARIZONA — Mexican farm worker Avelino Vazquez Navarro didn’t have air conditioning in the motor home where he died last month in Washington state as temperatures surged into the triple digits.

For the last dozen years, the 61-year-old spent much of the year working near Pasco, Washington, sending money to his wife and daughters in the Pacific coast state of Nayarit, Mexico, and traveling back every Christmas.

Now, the family is raising money to bring his remains home.

“If this motor home would have had AC and it was running, then it most likely would have helped,” said Franklin County Coroner Curtis McGary, who determined Vazquez Navarro’s death was heat-related, with alcohol intoxication as a contributing cause.

Most heat-related deaths involve homeless people living outdoors. But those who die inside without sufficient cooling also are vulnerable. They are typically older than 60, living alone and with a limited income.

Underscoring the inequities around energy and access to air conditioning as summers grow hotter, many victims are Black, Indigenous or Latino, such as Vazquez Navarro.

“Air conditioning is not a luxury, it’s a necessity,” said Mark Wolfe, executive director of the National Energy Assistance Directors’ Association, which represents state energy assistance programs. “It’s a public health issue, and it’s an affordability issue.”

The most vulnerable

People living in mobile homes or in aging trailers and RVs are especially likely to lack proper cooling. Nearly a quarter of the indoor heat deaths in Arizona’s Maricopa County last year were in those kinds of dwellings, which are transformed into a broiling tin can by the blazing desert sun.

“Mobile homes can really heat up because they don’t always have the best insulation and are often made of metal,” said Dana Kennedy, AARP director in Arizona, where many heat-related deaths occur.

Research shows mobile home dwellers are particularly at risk in blistering hot Phoenix, where 45-degree Celsius (113 Fahrenheit) weather is forecast for this weekend.

“People are exposed to the elements more than in other housing,” said Patricia Solís, executive director of the Knowledge Exchange for Resilience at Arizona State University, who worked on mapping hot weather impacts on mobile home parks for a state preparedness plan.

Worse, some parks bar residents from making modifications that could cool their homes, citing esthetic concerns. A new Arizona law required parks for the first time this summer to let residents install cooling methods such as window units, shade awnings and shutters.

In Arizona’s Maricopa County, home to Phoenix, 156 of 645 heat-related deaths last year occurred indoors in uncooled environments. In most cases, a unit was present but was not working, was without electricity or turned off, public health officials said.

One victim was Shirley Marie Kouplen, who died after being overcome by high temperatures inside her Phoenix mobile home amid a heat wave when the extension cord providing her electricity was unplugged.

Emergency responders recorded the 70-year-old widow’s body temperature at 41.7 C (107.1 F). Kouplen, who was diabetic and had high blood pressure, was rushed to a hospital, where she died.

Kouplen apparently was struggling financially, if the shabby condition of her mobile home was any indication. It still sits on Lot 60, surrounded by a chain-link fence with a locked gate and a dirt driveway overgrown with weeds.

It’s unclear how the cord got unplugged, if Kouplen had an electricity account or how she got her power.

“Losing your air conditioning is now a life-threatening event,” said Texas A&M University climate scientist Andrew Dessler, who grew up in hot, humid Houston in the 1970s. “You didn’t want to lose your air conditioning, but it wasn’t going to kill you. And now it is.”

Arizona’s regulated utilities have been banned since 2022 from cutting off power during the summer, following the 2018 death of a 72-year-old woman after Arizona Public Service disconnected her electricity over a $51 debt.

Ann Porter, spokesperson for Arizona Public Service, which provides electricity to homes in the park where Kouplen lived, said “due to privacy concerns” the company could not say if she had an account at the time of her death or in the past. Porter said the utility does not cut power from June 1 to Oct. 15.

Cutoffs can occur after those dates if mounting debts are not paid.

Arizona is among 19 states with shut-off protections, leaving about half of the U.S. population without safeguards against losing electricity during the summer, the National Energy Assistance Directors Association said in a new study.

Almost 20% of very-low-income families have no air conditioning at all, especially in places such as Washington state, where they weren’t commonly installed before climate-fueled heat waves grew increasingly stronger, more frequent and longer lasting.

Not only in the Southwest

In the Pacific Northwest, several hundred people died during a 2021 heat wave, prompting Portland, Oregon, to launch a program to provide portable cooling units to vulnerable, low-income people.

Chicago, better known for its cold winters, saw a heat wave kill 739 mostly older people over five days in 1995. Amid high humidity and temperatures over 37.7 C (100 F), most victims had no air conditioning or couldn’t afford to turn on their units.

In 2022, Chicago adopted a cooling ordinance after three women died in their apartments in a building for older adults on an unusually warm spring day. Certain residential buildings must now have at least one air-conditioned common area for cooling when the heat index exceeds 26.6 C (80 F) and cooling is unavailable in individual units.

Nonprofits in historically hotter areas such as Arizona also are trying to better address the inequities low-income people face during the sweltering summers. The Phoenix-based community agency Wildfire recently raised money to buy over $2 million worth of air conditioning equipment to help 150 households statewide over three years, Executive Director Kelly McGowan said.

Laws protect renters in some places. Phoenix landlords must ensure that air conditioning units cool to 28 C (82 F) or below and that evaporative coolers lower the temperature to 30C (86 F).

Palm Springs, California, and Las Vegas, Nevada, both desert cities, have ordinances requiring landlords to offer air conditioning in rental dwellings. Dallas, where temperatures can pass 43.3 C (110 F) in the summer, has a similar law.

But most renters pay their own electricity costs, leaving them to agonize whether they can afford to even turn on the cooling or how high to set the thermostat.

A new report estimates the average cost for U.S. families to keep cool from June to September will grow nationwide by 7.9% this year, from $661 in 2023 to $719 this summer.

Wolf noted the federal Low Income Home Energy Assistance Program, which grants money to states to help families pay for heating and cooling, is underfunded, with 80% going to heat homes in winter.
…

MEXICO CITY — Gliding above her neighborhood in a cable car on a recent morning, Sonia Estefanía Palacios Díaz scanned a sea of blue and black water tanks, tubes and cables looking for rain harvesting systems.

“There’s one!” she said, pointing out a black tank hooked up to a smaller blue unit with connecting tubes snaking up to the roof where water is collected.

“I’m always looking for different rainwater harvesting systems,” she said, smiling. “I’m also always looking for places to install one.”

Driven by prolonged drought and inconsistent public water delivery, many Mexico City residents are turning to rainwater. Pioneering company Isla Urbana, which does both nonprofit and for-profit work, has installed more than 40,000 rain catchment systems across Mexico since the company was founded 15 years ago. And Mexico City’s government has invested in the installation of 70,000 systems since 2019, still a drop in the bucket for the sprawling metropolis of around 9 million.

But there’s little education and limited resources to maintain the systems after installation, leading the systems to fall into disuse or for residents to sell off the parts.

Enter Palacios Díaz and a group of other women who make up the cooperative Pixcatl, which means harvest of water in the Indigenous Nahuatl language.

In lower-income areas like Iztapalapa — Mexico City’s most populous borough — the group tries to keep systems functioning while also educating residents on how to maintain them. That includes brainstorming their own designs and providing residents with low-cost options for additional materials.

Palacios Díaz has lived with water scarcity in Iztapalapa as far back as she can remember. “Here, people will get in line starting at 3 in the morning to get water (from distribution trucks) up until 2 in the afternoon,” she said from her mother’s home. “There was a time in which we went for more than a month without a regular supply of water.”

Earlier this year, the reservoirs that supply the capital were perilously low. Authorities reduced the amount of water being released and neighborhoods not accustomed to water scarcity faced a new reality.

Entering the rainy season, most of Mexico was in moderate to severe drought. Mexico’s reservoirs are beginning to approach half their capacity, but they haven’t filled by much, according to recent reports by the National Water Commission.

The country depends on the rains — which normally peter out in October — to fill the reservoirs, but the drought has taken them so low that that might take years.

That’s encouraged many Mexicans like Palacios Díaz to turn to rainwater harvesting.

At the height of the pandemic, she taught classes on urban farming and water harvesting at a local community space. It wasn’t until her students said they wanted to learn how to install and understand their own systems that she seriously considered taking a government course. After enrolling in a training program in 2022 to become an installer, she met other young women from the city interested in water harvesting systems and they formed the cooperative.

Near the skirt of a volcano on the fringes of Iztapalapa, Lizbeth Esther Pineda Castro, another member of the cooperative, and Palacios Díaz adjusted a ladder to reach the roof of a small house. The two-story home inherited by Sara Huitzil Morales and her niece sits in Iztapalapa’s Buenavista neighborhood.

Huitzil’s mother had qualified for a free water harvesting system from Mexico City’s government in 2021. After the installation, Huitzil requested Pixcatl’s maintenance since she wasn’t sure how to take care of the system.

Sporting their navy polos with the Pixcatl logo, Pineda and Palacios Díaz cleared debris off the roof so the system only collects fresh rain.

“We also add a little bit of soap and chlorine to clean the pipes,” said Palacios Díaz as she swept the liquid down a connecting tube that leads to the harvesting system.

Downstairs, they joined the other members of the cooperative in a courtyard to look at the giant 2,500-liter water tank, enough to serve Huitzil’s needs for several months when filled. The colossal container stood nearly as tall as Palacios Díaz. Another cooperative member cleared a filter of leaves and dirt.

Last, Palacios Díaz plopped in a couple of chlorine pills to clean and disinfect the water. The frequency of the entire maintenance process depends on several factors, including how much water is in the tank, how much has been used, and whether it has rained.

Huitzil said before the harvesting system, she endured water shortages and rationing. The publicly available water was consistently dirty and “dark like chocolate.” She often used the water that remained from doing laundry to clean the courtyard. Sometimes when dirty water would arrive, she would put it in buckets and wait for the dirt to settle to the bottom, using the cleanest for showering.

The system has transformed her daily use of water, and she doesn’t have to think twice about whether it’s safe. The system initially uses six filters, plus three more if the water is to be used for drinking.

“The water is good, it’s so good!” said Huitzil. “My clothes come out very clean and the water is sweet. You can even harvest it to be cleaner to drink.”

With more than 1.8 million residents, Iztapalapa has been one of the primary beneficiaries of Mexico City’s harvesting system program. But after two years, the city stopped giving away free systems when many residents, facing economic hardship and sometimes struggling to maintain the systems, sold off their parts.

“It should be easy to maintain, but it’s tedious,” Palacios Diaz said. “Unfortunately, we find ourselves in a scenario in which we not only have environmental problems, but economic problems.”

Loreta Castro Reguera, an architecture professor at Mexico’s National Autonomous University, focuses much of her work on water and urban design. She said rainwater harvesting is a great solution because during Mexico’s rainy season residents can use rainwater instead of water from the Cutzamala system — a reservoir that provides water to Mexico City and the State of Mexico.

Palacios Díaz dreams of rainwater systems in markets, malls, and other community spaces. The cooperative is also working on designs personalized for their clients’ needs — whether for a low-cost system or to fulfill a greater demand for water.

As women, she and the other members of Pixcatl want to set an example for those who want to get involved in water harvesting.

“I think it’s really beautiful we can inspire young girls and show women in another context,” said another member, Abigail López Durán, “that we can also use tools and aren’t afraid to get hurt.”
…

GENEVA — U.N. agencies warn that the demolition of a critical water facility in Rafah in the southern Gaza Strip increases the risk of infectious diseases as people are forced to drink unsafe water while sanitary conditions continue to deteriorate.

“Until recently, that reservoir served thousands and thousands of internally displaced people who had sought refuge in Rafah in the area,” James Elder, UNICEF spokesperson, told journalists at a briefing in Geneva on Tuesday.

“Now without it, vulnerable children and families are likely to be forced again increasingly to resort to unsafe water, so putting them again at all those risks that we see time after time, day after day in Gaza — dehydration, malnutrition, diseases,” he said.

The Israeli daily Haaretz reported Monday that the troops blew up the central reservoir “on the orders of the brigade commanders” but without receiving permission from the senior level of the Southern Command. It added that the incident was being investigated by Israel’s Military Police as “a suspected violation of international law.”

Infections spreading

Elder said the destruction of the Canada Well reservoir “is yet another grim reminder of the assaults on families who already are in desperate need of water.”

“We have seen spikes in diarrhea, in skin infections — all due to a lack of access to hygiene and a lack of access to water,” he said, noting that people in emergencies require a minimum of 15 liters (almost 4 gallons) of water per person per day.

Now, the range of water availability in Gaza has been reduced to between 2 and 9 liters per person, per day, and some people are getting just a fraction of that, Elder said.

“Somehow, people are holding on, but of course, we are now in that deathly cycle whereby children are very malnourished. There is immense heat. There is [a] lack of water. There is a horrendous lack of sanitation, and that is the cycle,” he said.

The World Health Organization reports a surge in infectious diseases in the Gaza Strip. As of July 7, it has recorded nearly 1 million cases of acute respiratory infections, 577,000 cases of acute watery diarrhea, 107,000 of acute jaundice syndrome and 12,000 of bloody diarrhea. It also has recorded nearly 200,000 cases of scabies, lice, skin rashes, chicken pox and other illnesses.

Polio threat

The recent identification of circulating vaccine-derived poliovirus type 2 in Gaza’s sewage system is of particular concern. Under prevailing conditions in Gaza, there is a high risk of spread of this paralytic, deadly disease within the Palestinian enclave and across borders.

“Having a vaccine-derived polio virus in the sewage very likely means that it is out there somewhere in people,” WHO spokesperson Christian Lindmeier said. “It most likely is in the population, but that does not necessarily mean that we see an outbreak of cases.

“But of course, we need to be prepared. We need to be utterly prepared. And we need vaccinations, and we need vaccination campaigns,” he said.

WHO Director-General Tedros Adhanom Ghebteyesus has announced that the organization will be sending more than 1 million doses of polio vaccine to Gaza to avert the spread of the disease.

“While no cases of polio have been recorded yet, without immediate action, it is just a matter of time before it reaches the thousands of children who have been left unprotected,” he said, adding that infants under 2 are especially vulnerable “because many have not been vaccinated over the nine months of conflict.”

Before Israel began its military offensive in Gaza following a brutal attack on Israel by Hamas militants on October 7, nearly the whole population of Gaza had been immunized against polio.

However, due to the impact of the conflict, “coverage of polio now is around 89%, down from around 99% before the conflict,” UNICEF’s Elder said. “Hence, there is an increased risk for children. Now, if the child gets the full course of the vaccine, then the risk of the child getting paralyzed by polio is negligible.

“This is why it is so critical that all children are immunized. But the mass displacement, the decimation of the health infrastructure, the tremendously insecure operating environment — they all make it much more difficult, hence putting more children at risk,” he said.

Cases of polio have declined by 99% since WHO launched its global polio eradication campaign in 1988.

WHO reports polio now is endemic only in Pakistan and Afghanistan. However, more than 30 countries, including Egypt and Israel, are subject to outbreaks. The reemergence of polio tends to occur in areas of conflict or instability and within countries with poor health systems.

“We were very, very close to eradicating polio fully,” WHO spokesperson Lindmeier said. “As you know, wartime, unfortunately, creates the situation where it is very difficult to get that last mile. And it has been less than a mile that we needed to go.

“There are a few pockets around the world. Hopefully, Gaza will not become another one,” he said.
…

…

Bangkok — Millions of lives could be put at risk unless urgent action is taken to curb the spread of drug-resistant malaria in Africa, according to a new paper published in the journal Science.

The paper says the parasite that causes malaria is showing signs of resistance to artemisinin, the main drug used to fight the disease, in several east African countries.

“Mutations indicating artemisinin-resistance have been found in more than 10% of malaria infected individuals in Ethiopia, Eritrea, Rwanda, Uganda, and Tanzania,” according to the report.

Artemisinin Combination Therapies, or ACTs, have been the cornerstone of malaria treatment in recent years — but there are worrying signs that they are becoming less effective, says report co-author Lorenz von Seidlein of the Mahidol Oxford Tropical Medicine Research Unit in Bangkok.

“We have increasing reports from eastern Africa saying that they have documented resistance against the first line treatments against malaria,” he says. “The first line treatments are artemisinin combination therapy – that has been used for the last 20 years and has worked excellently well. And it’s now not working quite as well as it used to do.”

It’s estimated that over one thousand children die every day from malaria in Africa. The World Health Organization estimates that the global death toll from malaria in 2022 — the most recent figures available — was 608,000.

Past lessons

Before artemisinin therapies were developed, chloroquine was the medicine most used to treat malaria. The report authors say that in the 1990s and early 2000s, signs that the malaria parasite was developing resistance to chloroquine were widely ignored.

“When chloroquine resistance slowly sneaked into Africa there was a whole wave of childhood mortality followed by it. So really, a large number of children — probably in the millions — died because chloroquine didn’t work as well as it used to do. And now we see these first signs that something similar is happening with the ACTs. And that is of course very worrying,” von Seidlein says.

Urgent action

The report authors urge policymakers and global funding bodies to act now to prevent artemisinin resistance taking hold.

Their recommendations include combining artemisinin drugs with other medicines.

“Combining an artemisinin derivative drug with two partner drugs in triple artemisinin combination therapies [TACTs] is the simplest, most affordable, readily implementable, and sustainable approach to counter artemisinin resistance,” the report says.

The authors also call for the rollout of new, more effective insecticides and mosquito nets; better training of community health workers; the rapid deployment of new malaria vaccines; and better monitoring of parasite mutations.

Southeast Asia

Many of these methods were used to halt the spread of artemisinin resistance in south-east Asia since 2014, notes von Seidlein.

“Ultimately, there was an understanding that this could be a major health emergency globally and so there were a lot of investments from funders for the from high-income countries towards these countries in the Greater Mekong sub-region to stop the spread of artemisinin resistant parasites,” he says.

The report says that sense of urgency must now be applied to tackling artemisinin resistance in Africa.

“We ask funders, specifically the Global Fund to Fight AIDS, Tuberculosis and Malaria [GFATM] and the U.S. Government’s President’s Malaria Initiative, to be visionary and to step up funding for malaria control and elimination programs to contain the spread of artemisinin resistance in Africa — as they have done effectively in Southeast Asia since 2014,” says report co-author Ntuli Kapologwe, the director of preventive services at Tanzania’s Ministry of Health.
…

The malaria parasite is showing signs of resistance to artemisinin, the main drug used to fight the disease, in parts of Africa. A new report warns of potentially millions more deaths without immediate health policy changes. Henry Ridgwell has more from Bangkok.
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GALAPAGOS ISLANDS, Ecuador — Warm morning light reflects from the remains of a natural rock arch near Darwin Island, one of the most remote islands in the Galapagos. In clear, deep blue water, thousands of creatures — fish, hammerhead sharks, marine iguanas — move in search of food.

The 2021 collapse of Darwin’s Arch, named for the famed British naturalist behind the theory of evolution, came from natural erosion. But its demise underscored the fragility of a far-flung archipelago that’s coming under increased pressure both from climate change and invasive species.

Warming oceans affect the food sources of many of the seagoing animals in the Galapagos. Marine iguanas — one of many species that are endemic, or unique, to the Galapagos — have a harder time finding the red and green algae they prefer. Sea turtles struggle to nest in warmer temperatures. Raising young gets harder as water warms and fewer nutrients are available.

While the Galapagos are known for a great multitude of species, their numbers aren’t unlimited.

“We have something of everything here – that’s why people say the Galapagos is so diverse – but we have a small number of each thing,” said Natasha Cabezas, a naturalist guide.

The Galapagos have always been sensitive to changes in ocean temperature. The archipelago itself is located where major ocean currents converge — cool from the south, warm from the north, and a cold upwelling current from the west. Then there’s El Nino, the periodic and natural Pacific Ocean warming that affects weather worldwide.

While temperatures vary depending on the season and other naturally-occurring climate events, ocean temperatures have been rising because of human-caused climate change as oceans absorb the vast majority of excess heat in the atmosphere. The ocean experienced its warmest decade since at least the 1800s in the last 10 years, and 2023 was the ocean’s warmest year on record.

Early June brings winter in the Southern Hemisphere, and the Cromwell current brings whale sharks, hammerheads, and massive sunfish to the surface. It also provides nutrients for penguins, marine iguanas and sea lions in search of food. As more of those animals make themselves known this season, scientists are tracking how they fared in the warming of the past year’s El Nino.

El Nino can bring food shortages for some species like marine iguanas and sea turtles, as the warmer ocean means dwindling food sources. Scientists observing the species have noted a significant decline in population numbers during El Nino events.

Marine iguanas swim like snakes through the water from rock to rock as waves crash against the shore of Fernandina Island. They latch themselves onto the undersea rocks to feed on algae growing there, while sea lions spin around them like puppies looking for someone to play with.

The iguanas were “one of the most affected species from El Niño last year and right now they are still recovering,” said Galapagos Conservancy Director Jorge Carrión.

As rising ocean temperatures threaten aquatic or seagoing life, on land there’s a different problem. Feral animals — cats, dogs, pigs, goats and cattle, none of them native — are threatening the unique species of the islands.

After the COVID-19 pandemic, many people are abandoning the dogs and cats they wanted to keep them company, Cabezas said.

“If you don’t take care of them they become a problem and now it’s a shame to see dogs everywhere. We have a big problem right now I don’t know what we’re going to do,” she said.

The non-native animals are a special threat to the giant tortoises closely associated with the Galapagos. The tortoises declined dramatically in the 19th century due to hunting and poaching, and authorities have worked to protect them from humans. It’s been illegal to kill a giant tortoise since 1933.

“In one night, a feral pig can destroy all nesting sites in an area,” Carrión said. Park rangers try to visit areas with nesting sites once a day, and kill pigs when they find them. But the pigs are elusive, Carrion said.

Feral cats feed on marine iguana hatchings, and both pigs and cats compete for food with the tortoises.

If invasive species and warming oceans weren’t enough, there’s the plastic that is a widespread problem in the world’s oceans. One recent study reported microplastics in the bellies of Galapagos penguins.

“There are no animals in the Galapagos that do not have microplastics in their food,” Carrión said.
…

Washington — New blood tests could help doctors diagnose Alzheimer’s disease faster and more accurately, researchers reported Sunday – but some appear to work far better than others.

It’s tricky to tell if memory problems are caused by Alzheimer’s. That requires confirming one of the disease’s hallmark signs — buildup of a sticky protein called beta-amyloid — with a hard-to-get brain scan or uncomfortable spinal tap. Many patients instead are diagnosed based on symptoms and cognitive exams.

Labs have begun offering a variety of tests that can detect certain signs of Alzheimer’s in blood. Scientists are excited by their potential, but the tests aren’t widely used yet because there’s little data to guide doctors about which kind to order and when. The U.S. Food and Drug Administration hasn’t formally approved any of them and there’s little insurance coverage.

“What tests can we trust?” asked Dr. Suzanne Schindler, a neurologist at Washington University in St. Louis who’s part of a research project examining that. While some are very accurate, “other tests are not much better than a flip of a coin.”

Demand for earlier Alzheimer’s diagnosis is increasing

More than 6 million people in the United States and millions more around the world  

have Alzheimer’s, the most common form of dementia. Its telltale “biomarkers” are brain-clogging amyloid plaques and abnormal tau protein that leads to neuron-killing tangles.

New drugs, Leqembi and Kisunla, can modestly slow worsening symptoms by removing gunky amyloid from the brain. But they only work in the earliest stages of Alzheimer’s and proving patients qualify in time can be difficult. Measuring amyloid in spinal fluid is invasive. A special PET scan to spot plaques is costly and getting an appointment can take months.

Even specialists can struggle to tell if Alzheimer’s or something else is to blame for a patient’s symptoms.

“I have patients not infrequently who I am convinced have Alzheimer’s disease and I do testing and it’s negative,” Schindler said.

New study suggests blood tests for Alzheimer’s can be simpler, faster

Blood tests so far have been used mostly in carefully controlled research settings. But a new study of about 1,200 patients in Sweden shows they also can work in the real-world bustle of doctors’ offices — especially primary care doctors who see far more people with memory problems than specialists but have fewer tools to evaluate them.

In the study, patients who visited either a primary care doctor or a specialist for memory complaints got an initial diagnosis using traditional exams, gave blood for testing and were sent for a confirmatory spinal tap or brain scan.

Blood testing was far more accurate, Lund University researchers reported Sunday at the Alzheimer’s Association International Conference in Philadelphia. The primary care doctors’ initial diagnosis was 61% accurate and the specialists’ 73% — but the blood test was 91% accurate, according to the findings, which also were published in the Journal of the American Medical Association.

Which blood tests for Alzheimer’s work best?

There’s almost “a wild West” in the variety being offered, said Dr. John Hsiao of the National Institute on Aging. They measure different biomarkers, in different ways.

Doctors and researchers should only use blood tests proven to have a greater than 90% accuracy rate, said Alzheimer’s Association chief science officer Maria Carrillo.

Today’s tests most likely to meet that benchmark measure what’s called p-tau217, Carrillo and Hsiao agreed. Schindler helped lead an unusual direct comparison of several kinds of blood tests, funded by the Foundation for the National Institutes of Health, that came to the same conclusion.

That type of test measures a form of tau that correlates with how much plaque buildup someone has, Schindler explained. A high level signals a strong likelihood the person has Alzheimer’s while a low level indicates that’s probably not the cause of memory loss.

Several companies are developing p-tau217 tests including ALZpath Inc., Roche, Eli Lilly and C2N Diagnostics, which supplied the version used in the Swedish study.

Who should use blood tests for Alzheimer’s?

Only doctors can order them from labs. The Alzheimer’s Association is working on guidelines and several companies plan to seek FDA approval, which would clarify proper use.

For now, Carrillo said doctors should use blood testing only in people with memory problems, after checking the accuracy of the type they order.

Especially for primary care physicians, “it really has great potential to help them in sorting out who to give a reassuring message and who to send on to memory specialists,” said Dr. Sebastian Palmqvist of Lund University, who led the Swedish study with Lund’s Dr. Oskar Hansson.

The tests aren’t yet for people who don’t have symptoms but worry about Alzheimer’s in the family — unless it’s part of enrollment in research studies, Schindler stressed.

That’s partly because amyloid buildup can begin two decades before the first sign of memory problems, and so far, there are no preventive steps other than basic advice to eat healthy, exercise and get enough sleep. But there are studies underway testing possible therapies for people at high risk of Alzheimer’s, and some include blood testing.
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KENITRA, Morocco — Golden fields of wheat no longer produce the bounty they once did in Morocco. A six-year drought has imperiled the country’s entire agriculture sector, including farmers who grow cereals and grains used to feed humans and livestock.

The North African nation projects this year’s harvest will be smaller than last year in both volume and acreage, putting farmers out of work and requiring more imports and government subsidies to prevent the price of staples like flour from rising for everyday consumers.

“In the past, we used to have a bounty — a lot of wheat. But during the last seven or eight years, the harvest has been very low because of the drought,” said Al Housni Belhoussni, a small-scale farmer who has long tilled fields outside of the city of Kenitra.

Belhoussni’s plight is familiar to grain farmers throughout the world confronting a hotter and drier future. Climate change is imperiling the food supply and, in regions like North Africa, shrinking the annual yields of cereals that dominate diets around the world — wheat, rice, maize and barley.

The region is one of the most vulnerable in the world to climate change. Delays to annual rains and inconsistent weather patterns have pushed the growing season later in the year and made planning difficult for farmers.

In Morocco, where cereals account for most of the farmed land and agriculture employs the majority of workers in rural regions, the drought is wreaking havoc and touching off major changes that will transform the makeup of the economy. It has forced some to leave their fields fallow. It has also made the areas they do elect to cultivate less productive, producing far fewer sacks of wheat to sell than they once did.

In response, the government has announced restrictions on water use in urban areas — including on public baths and car washes — and in rural ones, where water going to farms has been rationed.

“The late rains during the autumn season affected the agriculture campaign. This year, only the spring rains, especially during the month of March, managed to rescue the crops,” said Abdelkrim Naaman, the chairman of Nalsya. The organization has advised farmers on seeding, irrigation and drought mitigation as less rain falls and less water flows through Morocco’s rivers.

The Agriculture Ministry estimates that this year’s wheat harvest will yield roughly 3.1 billion kilograms, far less than last year’s 5.5 billion kilograms — a yield that was still considered low. The amount of land seeded has dramatically shrunk as well, from 36,700 square kilometers to 9,540 square miles 24,700 square kilometers.

Such a drop constitutes a crisis, said Driss Aissaoui, an analyst and former member of the Moroccan Ministry for Agriculture.

“When we say crisis, this means that you have to import more,” he said. “We are in a country where drought has become a structural issue.”

Leaning more on imports means the government will have to continue subsidizing prices to ensure households and livestock farmers can afford dietary staples for their families and flocks, said Rachid Benali, the chairman of the farming lobby COMADER.

The country imported nearly 2.5 million tons of common wheat between January and June. However, such a solution may have an expiration date, particularly because Morocco’s primary source of wheat, France, is facing shrinking harvests as well.

The United Nations’ Food and Agriculture Organization ranked Morocco as the world’s sixth-largest wheat importer this year, between Turkey and Bangladesh, which both have much bigger populations.

“Morocco has known droughts like this and in some cases known droughts that las longer than 10 years. But the problem, this time especially, is climate change,” Benali said.
…