YCLOAK

CHICAGO, ILLINOIS — H5N1 bird flu had been confirmed in a pig in a backyard farm in Oregon, the first detection of the virus in swine in the country, the U.S. Department of Agriculture said on Wednesday.

Pigs represent a particular concern for the spread of bird flu because they can become co-infected with bird and human viruses, which could swap genes to form a new, more dangerous virus that can more easily infect humans.

The USDA said there is no risk to the nation’s pork supply from the Oregon case and that the risk to the public from bird flu remains low.

Pigs were the source of the H1N1 flu pandemic in 2009-2010, and have been implicated as the source of others, said Richard Webby, a St. Jude Children’s Research Hospital virologist who studies flu in animals and birds for the World Health Organization.

The finding of the virus in a small farm makes the pig infection less of a concern than if it had been detected in a commercial pig farm, he said.

“I think it probably doesn’t increase the risk much, but surely, if this virus starts transmitting in pigs, that absolutely increases the risk,” he said.

The Oregon farm has been quarantined, and other animals there, including sheep and goats, are under surveillance, the USDA said.

Pigs and poultry on the farm were culled to prevent the spread of the virus and enable additional testing of the swine, the USDA said. Tests are still pending for two of the pigs, the agency said.

The swine case originated with wild birds and not from a poultry or dairy farm, a USDA spokesperson said. Wild bird migration has carried bird flu to poultry flocks and cattle herds.

The case was one factor that prompted the USDA to broaden its bird flu surveillance to include nationwide bulk milk testing, which the agency announced on Wednesday, Agriculture Secretary Tom Vilsack told Reuters in an interview.

“While it’s a different variation of the virus and it is tied to wild birds, it is a factor to make sure that we understand and appreciate exactly where the virus is in dairy and in bovine,” he said.

The pigs on the Oregon farm were not intended for the commercial food supply, the USDA said.

The agency said that poultry and swine on the backyard farm shared water sources, housing and equipment, which have all served as pathways for transmitting the virus between animals in other states.

The detection is a warning for pig farmers to be on the lookout for further infections, said Marie Culhane, a professor of veterinary population medicine at the University of Minnesota who has researched flu viruses in swine.

“People need to start increasing their plans to deal with it if it should happen in another herd and another herd,” Culhane said. “Pigs are just really good at picking up influenza viruses.”

This year, 36 people have tested positive for bird flu as the virus has spread to nearly 400 dairy herds. All but one of the people were farm workers who had known contact with infected animals.

Since 2022, the virus has wiped out more than 100 million poultry birds in the nation’s worst-ever bird flu outbreak.
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LONDON — Britain has detected its first case of new mpox variant clade Ib, the country’s health security agency (UKHSA) said Wednesday, adding that the risk to the population remained low.  

The clade Ib variant is a new form of the virus that was declared a global health emergency by the World Health Organization (WHO) in August after an outbreak in the Democratic Republic of Congo spread to neighboring countries in Africa.  

The case, in a patient who had recently traveled to affected countries in Africa, was detected in London and the individual has been transferred to a specialist hospital, the UKHSA said.  

Close contacts of the case are being followed up by UKHSA and partner organizations, the UKHSA added.  

There have been cases of mpox clade Ib reported in Burundi, Rwanda, Uganda, Kenya, Sweden, India and Germany, as well as Congo. It is a different form of the virus from clade II, which spread globally in 2022, largely among men who have sex with men.  

Mpox is a viral infection that typically causes flu-like symptoms and pus-filled lesions, and while usually mild it can kill. Clade Ib is thought to cause more severe disease than clade II.  

Both forms can be transmitted through close physical contact, including sexual contact.  

The United Kingdom authorities said they would not provide any more details about the patient, but added that the person’s contacts were being followed up and would be offered testing and vaccination as needed, as well as further care if they test positive or have symptoms.  

According to the latest WHO figures, there have been more than 44,000 confirmed and suspected cases of mpox in Africa this year, and more than 1,000 deaths, largely in Congo.
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london — More than 8 million people were diagnosed with tuberculosis last year, the World Health Organization said Tuesday, the highest number recorded since the U.N. health agency began keeping track.

About 1.25 million people died of TB last year, the new report said, adding that TB likely returned to being the world’s top infectious disease killer after being replaced by COVID-19 during the pandemic. The deaths are almost double the number of people killed by HIV in 2023.

WHO said TB continues to mostly affect people in Southeast Asia, Africa and the Western Pacific; India, Indonesia, China, the Philippines and Pakistan account for more than half of the world’s cases.

“The fact that TB still kills and sickens so many people is an outrage, when we have the tools to prevent it, detect it and treat it,” WHO Director-General Tedros Adhanom Ghebreyesus said in a statement.

TB deaths continue to fall globally, however, and the number of people being newly infected is beginning to stabilize. The agency noted that of the 400,000 people estimated to have drug-resistant TB last year, fewer than half were diagnosed and treated.

Tuberculosis is caused by airborne bacteria that mostly affects the lungs. Roughly a quarter of the global population is estimated to have TB, but only about 5%-10% of those develop symptoms.

Advocacy groups, including Doctors Without Borders, have long called for the U.S. company Cepheid, which produces TB tests used in poorer countries, to make them available for $5 per test to increase availability. Earlier this month, Doctors Without Borders and 150 global health partners sent Cepheid an open letter calling on them to “prioritize people’s lives” and to urgently help make TB testing more widespread globally.
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The Iowa Department of Health and Human Services on Monday confirmed the death of a middle-aged eastern Iowa resident from Lassa fever.

The individual had recently returned from travel to West Africa, where it is believed the person contracted the virus, the state health department said.

The U.S. Centers for Disease Control and Prevention is working to confirm the diagnosis of Lassa fever, the state health department said. The CDC said it assesses the risk to the general public to be extremely low.

Lassa fever is a viral disease common in West Africa, but rarely seen in the United States.

There have been eight travel-associated cases of Lassa fever in the United States in the past 55 years, according to the Iowa health department.

In West Africa, the Lassa virus is carried by rodents and spread to humans through contact with urine or droppings of infected rodents.

About 100,000 to 300,000 cases of Lassa fever and 5,000 related deaths occur in West Africa each year, according to the CDC.
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Islamabad — Pakistan and neighboring Afghanistan simultaneously launched fresh vaccination campaigns against polio Monday amid a resurgence in cases in the only two countries globally where the virus continues to be endemic and paralyze children. 

The World Health Organization reported 64 polio infections this year: 41 from Pakistan and 23 from Afghanistan, up from six each in both countries in 2023.

Pakistani officials said the weeklong house-to-house nationwide campaign that was rolled out Monday enlists 400,000 polio workers, who aim to vaccinate over 45 million children under five against the paralytic disease.

“This is Pakistan’s third nationwide campaign this year, launched in response to the alarming increase in polio cases across 71 districts,” said Ayesha Raza Farooq, the prime minister’s point-person for polio eradication.

More than half the infections in 2024 are located in southwestern Balochistan province, which sits on the Afghan border and is “facing an intense transmission” of the poliovirus. The southern province of Sindh has recorded 12 cases this year, while other regions in Pakistan, a country of more than 240 million, have reported the remaining cases, according to Pakistan’s polio eradication program.

Anwarul Haq, the coordinator of the National Emergency Operations Center for Polio Eradication, urged parents to cooperate with health teams in protecting their children against the crippling disease, stressing that there is no cure for polio. “With the threat at an all-time high, we must act as one nation to keep our children safe through vaccination,” he stated.   

Local and WHO officials attribute the resurgence of poliovirus in Pakistan to vaccine boycotts in rural areas stemming from the false propaganda that these initiatives are a Western plot to sterilize Muslim children.

Additionally, anti-state militants in violence-hit districts bordering Afghanistan occasionally attack vaccinators and their police escorts, suspecting them of spying for the government. The violence has resulted in the deaths of dozens of polio workers and police personnel, including at least two vaccinators and seven police members killed this year.

Afghanistan 

Meanwhile, health officials in Taliban-led Afghanistan announced Monday the opening of a three-day polio-vaccination campaign, saying it aims to reach 6.2 million children under five in 16 of the country’s 34 provinces. The target areas are primarily located close to the border with Pakistan.

The latest round of this year’s anti-polio campaign in Afghanistan began after nearly a two-month delay because Taliban authorities abruptly halted house-to-house vaccine deliveries in the southern province of Kandahar without publicly stating any reason. Instead, de facto Afghan authorities stressed the need to conduct vaccinations for children from site to site and mosque to mosque.

In a report released last month, an independent monitoring board of the Global Polio Eradication Initiative believed that the Taliban’s action had stemmed from their “administration’s concerns about covert surveillance activities.” The report quoted Taliban officials as explaining that their leadership is living in Kandahar and has concerns about their security.

Kandahar, regarded as the unofficial capital of Afghanistan under Taliban rule, is where the militant group’s reclusive supreme leader, Hibatullah Akhundzada, resides and governs the country through his decrees based on his strict interpretation of Islam.

The Taliban chief has banned most Afghan women from public and private sector workplaces and barred girls from receiving an education beyond the sixth grade.

WHO officials say eradicating polio in Afghanistan requires comprehensive integration of large migrant populations into the vaccination program. They say it is also crucial to reach out to groups that refuse vaccination and establish a female public health workforce dedicated to the polio initiative to tackle multiple challenges facing polio-eradication efforts in the impoverished country.
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LOS ANGELES — McDonald’s announced Sunday that Quarter Pounders will again be on its menu at hundreds of its restaurants after testing ruled out beef patties as the source of the outbreak of E. coli poisoning tied to the popular burgers that killed one person and sickened at least 75 others across 13 states.

The U.S. Food and Drug Administration continues to believe that slivered onions from a single supplier are the likely source of contamination, McDonald’s said in a statement. It said it will resume selling the Quarter Pounder at affected restaurants — without slivered onions — in the coming week.

As of Friday, the outbreak had expanded to at least 75 people sick in 13 states, federal health officials said. A total of 22 people had been hospitalized, and two developed a dangerous kidney disease complication, the Centers for Disease Control and Prevention said. One person has died in Colorado.

Early information analyzed by the FDA showed that uncooked slivered onions used on the burgers “are a likely source of contamination,” the agency said. McDonald’s has confirmed that Taylor Farms, a California-based produce company, was the supplier of the fresh onions used in the restaurants involved in the outbreak, and that they had come from a facility in Colorado Springs, Colorado.

McDonald’s pulled the Quarter Pounder burger from menus in several states — mostly in the Midwest and Mountain states — when the outbreak was announced Tuesday. McDonald’s said Friday that slivered onions from the Colorado Springs facility were distributed to approximately 900 of its restaurants, including some in transportation hubs like airports.

The company said it removed slivered onions sourced from that facility from its supply chain on Tuesday. McDonald’s said it has decided to stop sourcing onions from Taylor Farms’ Colorado Springs facility “indefinitely.”

The 900 McDonald’s restaurants that normally received slivered onions from Taylor Farms’ Colorado Springs facility will resume sales of Quarter Pounders without slivered onions, McDonald’s said.

Testing by the Colorado Department of Agriculture ruled out beef patties as the source of the outbreak, McDonald’s said.

The Department of Agriculture received multiple lots of fresh and frozen beef patties collected from various Colorado McDonald’s locations associated with the E. coli investigation. All samples were found to be negative for E. coli, the department said.

Taylor Farms said Friday that it had preemptively recalled yellow onions sent to its customers from its Colorado facility and continues to work with the CDC and the FDA as they investigate.

While it remains unclear if the recalled onions were the source of the outbreak, several other fast-food restaurants — including Taco Bell, Pizza Hut, KFC and Burger King — pulled onions from some menus in certain areas this week.

Colorado had the most illnesses reported as of Friday, with 26 cases. At least 13 people were sickened in Montana, 11 in Nebraska, 5 each in New Mexico and Utah, 4 each in Missouri and Wyoming, two in Michigan and one each in Iowa, Kansas, Oregon, Wisconsin and Washington, the CDC reported.

McDonald’s said Friday it didn’t pull the Quarter Pounder from any additional restaurants and noted that some cases in states outside the original region were tied to travel.

The CDC said some people who got sick reported traveling to other states before their symptoms started. At least three people said they ate at McDonald’s during their travel. Illnesses were reported between Sept. 27 and Oct. 11.

The outbreak involves infections with E. coli 0157:H7, a type of bacteria that produces a dangerous toxin. It causes about 74,000 infections in the U.S. annually, leading to more than 2,000 hospitalizations and 61 deaths each year, according to CDC.

Symptoms of E. coli poisoning can occur quickly, within a day or two of eating contaminated food. They typically include fever, vomiting, diarrhea or bloody diarrhea and signs of dehydration — little or no peeing, increased thirst and dizziness. The infection is especially dangerous for children younger than 5, people who are elderly, pregnant or who have weakened immune systems.
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The good news: You will get a glorious extra hour of sleep. The bad: It’ll be dark as a pocket by late afternoon for the next few months in the U.S. 

Daylight saving time ends at 2 a.m. local time next Sunday, Nov. 3, which means you should set your clock back an hour before you go to bed. Standard time will last until March 9 when we will again “spring forward” with the return of daylight saving time. 

That spring time change can be tougher on your body. Darker mornings and lighter evenings can knock your internal body clock out of whack, making it harder to fall asleep on time for weeks or longer. Studies have even found an uptick in heart attacks and strokes right after the March time change. 

“Fall back” should be easier. But it still may take a while to adjust your sleep habits, not to mention the downsides of leaving work in the dark or trying exercise while there’s still enough light. Some people with seasonal affective disorder, a type of depression usually linked to the shorter days and less sunlight of fall and winter, may struggle, too. 

Some health groups, including the American Medical Association and American Academy of Sleep Medicine, have said it’s time to do away with time switches and that sticking with standard time aligns better with the sun — and human biology. 

Most countries do not observe daylight saving time. For those that do — mostly in Europe and North America — the date that clocks are changed varies. 

Two states — Arizona and Hawaii — don’t change and stay on standard time. 

Here’s what to know about the twice yearly ritual. 

How the body reacts to light 

The brain has a master clock that is set by exposure to sunlight and darkness. This circadian rhythm is a roughly 24-hour cycle that determines when we become sleepy and when we’re more alert. The patterns change with age, one reason that early-to-rise youngsters evolve into hard-to-wake teens. 

Morning light resets the rhythm. By evening, levels of a hormone called melatonin begin to surge, triggering drowsiness. Too much light in the evening — that extra hour from daylight saving time — delays that surge and the cycle gets out of sync. 

And that circadian clock affects more than sleep, also influencing things like heart rate, blood pressure, stress hormones and metabolism. 

How do time changes affect sleep? 

Even an hour change on the clock can throw off sleep schedules — because even though the clocks change, work and school start times stay the same. 

That’s a problem because so many people are already sleep deprived. About 1 in 3 U.S. adults sleep less than the recommended seven-plus hours nightly, and more than half of U.S. teens don’t get the recommended eight-plus hours on weeknights. 

Sleep deprivation is linked to heart disease, cognitive decline, obesity and numerous other problems. 

How to prepare for the time change 

Some people try to prepare for a time change jolt by changing their bed times little by little in the days before the change. There are ways to ease the adjustment, including getting more sunshine to help reset your circadian rhythm for healthful sleep. 

Will the U.S. ever get rid of the time change? 

Lawmakers occasionally propose getting rid of the time change altogether. The most prominent recent attempt, a now-stalled bipartisan bill named the Sunshine Protection Act, proposes making daylight saving time permanent. Health experts say the lawmakers have it backward — standard time should be made permanent. 
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washington — A NASA astronaut who was hospitalized upon return from the International Space Station for an unspecified medical condition was released Saturday in “good health,” the U.S. space agency said. 

The four-member Crew-8 mission splashed down off the coast of Florida early Friday after nearly eight months aboard the orbital laboratory.   

NASA did not reveal which of the astronauts was hospitalized nor the reason, citing medical privacy.   

However, it said in a blog post that the crew member has returned to the Johnson Space Center in Houston “in good health and will resume normal post-flight reconditioning with other crew members.”   

On its way back to Earth, the SpaceX Dragon executed a normal re-entry and splashdown, and recovery of the crew and spacecraft was without incident, NASA said.   

But during routine medical assessments on the recovery ship, an “additional evaluation of the crew members was requested out of an abundance of caution,” it added, without elaborating. 

NASA astronauts Matthew Dominick, Michael Barratt and Jeanette Epps, and Roscosmos cosmonaut Alexander Grebenkin were all flown to Ascension Sacred Heart Pensacola.   

Three were subsequently released, while one remained at the hospital “under observation as a precautionary measure.” 
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CAPE CANAVERAL, Florida — A NASA astronaut was taken to the hospital for an undisclosed medical issue after returning from a nearly eight-month space station stay extended by Boeing’s capsule trouble and Hurricane Milton, the space agency said Friday.

A SpaceX capsule carrying three Americans and one Russian parachuted before dawn into the Gulf of Mexico just off the Florida coast after undocking from the International Space Station at midweek. The capsule was hoisted onto the recovery ship where the four astronauts had routine medical checks.

Soon after splashdown, a NASA astronaut had a “medical issue” and the crew was flown to a hospital in Pensacola, Florida, for additional evaluation “out of an abundance of caution,” the space agency said in a statement.

The astronaut, who was not identified, was in stable condition and remained at the hospital as a “precautionary measure,” NASA said.

The space agency said it would not share details about the astronaut’s condition, citing patient privacy.

The other three astronauts were discharged and returned to NASA’s Johnson Space Center in Houston.

It can take days or even weeks for astronauts to readjust to gravity after living in weightlessness for several months.

The astronauts should have been back two months ago. But their homecoming was stalled by problems with Boeing’s new Starliner astronaut capsule, which came back empty in September because of safety concerns. Then Hurricane Milton interfered, followed by another two weeks of high wind and rough seas.

SpaceX launched the four — NASA’s Matthew Dominick, Michael Barratt and Jeanette Epps, and Russia’s Alexander Grebenkin — in March. Barratt, the only space veteran going into the mission, acknowledged the support teams back home that had “to replan, retool and kind of redo everything right along with us … and helped us to roll with all those punches.”

Their replacements are the two Starliner test pilots Butch Wilmore and Suni Williams, whose own mission went from eight days to eight months, and two astronauts launched by SpaceX four weeks ago. Those four will remain up there until February.

The space station is now back to its normal crew size of seven — four Americans and three Russians — after months of overflow.
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BERLIN, Germany — Close to 200 countries are scheduled to negotiate a new climate finance target for the Global South at the U.N. Climate Change Conference, or COP29, in Baku, Azerbaijan, in November.  

Dubbed the “Finance COP,” next month’s conference is expected to see focused discussions on a New Collective Quantified Goal on Climate Finance, or NCQG. It defines a new target for monetary support from historic emitters – mostly countries in the Global North – to address climate needs in poorer countries.    

Surging climate needs  

In 2009, countries including the United States and the European Union agreed to contribute $100 billion collectively each year by 2020, but an OECD report showed that they struggled to meet that goal over the years. Worse still, much of the climate finance came in the form of loans, which critics say have piled more pressure on developing countries already drowning in debt.    

The new negotiations come after a spate of extreme weather conditions intensified by human-caused climate change. July, for instance, witnessed the three hottest days ever recorded. Scientists said in an article on BioScience that as fossil fuel emissions reached an all-time high, the Earth is on track for 2.7 degrees Celsius warming by 2100, far above the 1.5 degrees Celsius target established in the 2015 Paris Agreement.   

To combat the burgeoning crisis, developing countries will now need more than $100 billion a year, with estimates ranging up to $6 trillion by 2030. Even that does not sufficiently cover measures to adapt to already inevitable climate change, according to a 2021 U.N. report. 

Conference host Azerbaijan in July launched the Climate Finance Action Fund with an initial goal of raising $1 billion from fossil-fuel producing countries and companies. 

Nations are likely to reach a compromise at the lower end of a NCQG goal, according to Irene Monasterolo, professor of climate finance at the Utrecht University. 

“These results of the negotiations may not be able to address the current need for climate finance in low-income countries, which are massively affected already now by climate risk,” Monasterolo told VOA. “The focus so far has been mostly on mitigation [reducing emissions] projects and measures, while adaptation investments are lagging behind.”   

Adaptation finance   

While adaptation finance has gone up over the years, mitigation still accounts for the majority of current climate finance, the OECD report revealed. Monasterolo said the scale of adaptation finance ultimately depends on mitigation efforts.    

“We don’t see bold plans for mitigation that would be needed to achieve the 1.5 degrees Celsius target, including the Global North. We have instead some issues of policy reversal and some major economies and polluting countries like the U.S. stepping back and in Europe,” she added.    

“The science is clear. To limit global warming to below 2 degrees Celsius compared to pre-industrial times, we need to drop production, extraction, use of fossil fuels and related carbon activities and focus on renewables, and low-carbon activities should go up. But that’s not happening. In the latest geopolitical crisis, we increased our dependency on fossil fuels.”  

The wars in the Middle East and Russia have put energy security at risk, according to the International Energy Agency. While a record high level of clean energy came online last year, emissions from the energy sector also broke records.    

Another reason for low adaptation finance, Monasterolo said, is the complexity of assessing climate risks. “We need to work on how to integrate forward-looking climate risk into investors and financial authorities’ models. Market-based approaches based on past data are a poor proxy of what could happen in the near future with ongoing climate change.”   

Loss and damage fund   

At COP28 in Dubai last year, countries agreed to set up a voluntary fund for historic emitters to pay for the damage caused by climate disasters in vulnerable developing countries. Western countries also called for large emitters like China to contribute. Negotiators are expected to continue the discussion at COP29.    

For now, it remains unclear whether the loss and damage fund will be included in the new NCQG, according to Karoliina Hurri, researcher at the Center on Climate Politics and Security at the Finnish Institute of International Affairs. 

The fund “is defined as voluntary, so it’s not based on the same categorization of developed and developing countries. … Some developed countries argue that the loss and damage fund is not part of the mandate and should be negotiated separately from this.”  

Looming NDCs   

As countries are slated to declare new and more ambitious national green goals by February 2025, COP29 is expected to be a big push.   

“I am afraid we won’t see ambitious enough NDCs [national determined contributions], but I think this is really important at this COP, especially the discussion of how to ensure the [recommended] outcomes of last year’s Global Stocktake, and the discussion about transitioning away from fossil fuels,” Hurri explained. 

Hurri said many countries said they would lead by example to announce goals aligned with the 1.5 degrees Celsius warming goal. “But at the same time, nations can decide for themselves what the alignment means. This clarifies how difficult it is to reach the NDC.”   

At COP28, countries signed a historic deal to start transitioning away from polluting fossil fuels. Hurri said, however, it remains to be seen how the phases translate into actions. “Do we see, for example, schedules of roadmaps on how this process is planned on the national level?”   

Pivotal US election   

The U.S. election results could have a large impact on the implementation of potential negotiation results, including cooperation measures with the world’s biggest emitting nation, China, according to Hurri. 

“I have not seen very detailed climate policy arguments from either of the candidates, although we know that they have very different views on climate change. … We know what happened last time during President [Donald] Trump’s term that the U.S. decreased financial contribution for climate,” she said.    

COP29 will also mark the first cooperation talks between the new envoys from the United States and China — John Podesta and Liu Zhenmin. They had a working group meeting in Beijing in early September, in which they agreed to host a summit on methane and non-carbon greenhouse gases during the climate conference.   

“While the U.S. election might not influence the cooperation at this year’s COP, the election outcome can have an influence on the credibility of their cooperation in the long term on a high level,” Hurri said.   
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Four astronauts returned to Earth on Friday after a nearly eight-month space station stay extended by Boeing’s capsule trouble and Hurricane Milton.

A SpaceX capsule carrying the crew parachuted before dawn into the Gulf of Mexico just off the Florida coast after undocking from the International Space Station mid-week.

The three Americans and one Russian should have been back two months ago. But their homecoming was stalled by problems with Boeing’s new Starliner astronaut capsule, which came back empty in September because of safety concerns. Then Hurricane Milton interfered, followed by another two weeks of high wind and rough seas.

SpaceX launched the four — NASA’s Matthew Dominick, Michael Barratt and Jeanette Epps, and Russia’s Alexander Grebenkin — in March. Barratt, the only space veteran going into the mission, acknowledged the support teams back home that had “to replan, retool and kind of redo everything right along with us … and helped us to roll with all those punches.”

Their replacements are the two Starliner test pilots Butch Wilmore and Suni Williams, whose own mission went from eight days to eight months, and two astronauts launched by SpaceX four weeks ago. Those four will remain up there until February.

The space station is now back to its normal crew size of seven — four Americans and three Russians — after months of overflow.
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Maulana Tayyab Qureshi, the top cleric in Pakistan’s Khyber Pakhtunkhwa Province, has seen up close the devastating effects of polio.

Two of his own kin were once paralyzed, victims of a scourge that has been vanquished worldwide yet refuses to go away from Pakistan and neighboring Afghanistan.

“Had their parents not neglected [to have their children vaccinated], their children wouldn’t be disabled today,” Qureshi said of his relatives.

As the chief khateeb, or Friday prayer leader, of the northwestern province, Qureshi preaches this message at every opportunity — Friday sermons at his 17th century Mahabat Khan Mosque in Peshawar, Eid prayers when upward of 40,000 people congregate, meetings with village elders.

“I’m very clear cut: I tell them, it’s free. It doesn’t cost you anything. Why don’t you take it seriously?” Qureshi said in an interview with VOA.

Qureshi is not the only Pakistani cleric advocating vaccination. Several renowned scholars have issued decrees in its support, with a notable shift in attitudes. Vaccine hesitancy, an intractable obstacle to eradicating polio, has waned, he said.

A once infamous bastion of vaccine resistance outside Peshawar has now embraced immunization.

“The fatwas have had a great impact,” Qureshi said.

Yet, as Pakistan and Afghanistan seek to eradicate polio, misinformation remains a key hurdle. While immunization rates are generally high in both countries, pockets of resistance persist along the border, jeopardizing eradication efforts.

To counter vaccine misinformation, public health officials increasingly have turned to influential clerics like Qureshi. As the trusted voices within their communities, these religious leaders play a crucial role in dispelling harmful myths and misconceptions about vaccines, experts say.

“The best way to fight through this is empowering trusted voices in communities to push back on it and provide real information,” said Kai Ruggeri, a Columbia University health policy professor who has written about vaccine disinformation.

The stakes are high. Afghanistan and Pakistan are the only countries where polio remains endemic. And as World Polio Day arrives this year, there are renewed concerns over their ability to eliminate the disease.

The neighboring countries were once on the brink of going polio-free. But persistent insecurity coupled with cross-border movements has fueled a resurgence.

Pakistan has recorded 40 cases and Afghanistan at least 20, this year. This marks a significant increase from the six cases each reported last year.

A setback came last month when more than 1 million Pakistani children missed vaccinations, and Afghanistan’s Taliban briefly suspended immunization campaigns.

Oliver Rosenbauer, a spokesman for WHO’s polio eradication program in Geneva, noted that misinformation is not the only obstacle to eliminating polio; a lack of infrastructure, insecurity and population density also contribute.

“The important point is the polio virus doesn’t care why a child is not vaccinated,” Rosenbauer said in an interview. “It’s very, very good at finding that unvaccinated child.”

Polio, a crippling disease that can lead to paralysis and death, has long been eradicated globally thanks to universal immunization efforts. For most people around the world, polio is a distant memory or even a relic of history.

But in Afghanistan and Pakistan, the disease remains a stark reality despite significant progress in recent decades. Its scars are visible to those who look, Rosenbauer said.

“It’s a disease that parents still see,” he said. “If you walk around Karachi or Kabul, you’ll still see people with polio on the streets.”

This “respect for the disease” explains why vaccine hesitancy remains around 1.5% in Afghanistan and Pakistan, significantly lower than many Western countries.

Yet in densely populated areas, such as the border regions of Afghanistan and Pakistan, lingering resistance can prevent efforts to eradicate the virus.

Leading the charge against the vaccine, militants on both sides of the border have waged violent attacks on polio workers and their escorts. Their claim that the vaccine program violates Islamic law and is used for surveillance has fueled resistance.

Hundreds have been killed in both Pakistan and Afghanistan.

In January, at least five policemen were killed and more than a dozen injured in a major attack on polio teams and security personnel in northwestern Pakistan.

According to the Emergency Operations Center in Khyber Pakhtunkhwa, militants have carried out 21 attacks against polio teams and security escorts in Pakistan this year.

Mainstream clerics have pushed back.

In 2019, prominent Islamic scholars from Afghanistan and Pakistan declared the polio vaccine safe and Sharia-compliant. They stressed the “moral duty” of parents to have their children vaccinated.

In 2022, the al-Azhar University, the Sunni Muslim world’s most prestigious institution of religious education, warned against decrees banning the polio vaccine in Pakistan.

Last month, nearly 200 renowned religious scholars in Khyber Pakhtunkhwa declared support for polio vaccination.

Qureshi, the chief khateeb of KP, was among them.

The scholars “took a strong stand not only regarding the polio vaccine but all health measures by the ministry of health,” Qureshi said.

Across the border, Taliban health officials are waging their own campaign against vaccine misinformation even as attacks on health workers, often claimed by ISIS, have persisted.

Ehsanul Haq Hanafi, a cleric and senior official in the health ministry, understands the clergy’s influence in Afghan society.

“People listen to the ulema and accept what they say,” Hanafi said in an interview with VOA.

Among the myriad misconceptions about the vaccine, he said, some Afghans believe it corrupts morals or causes sterility. Others think it can accelerate puberty, he said.

“This is unscientific and baseless disinformation,” he said.

To combat this, Hanafi travels around the country to meet with locals and mullahs to convince the skeptics. While some clerics remain opposed, most accept the vaccine once its benefits are explained, he said.

“We can’t convince 100% of the people, but 80% agree with us and have their children vaccinated,” Hanafi said.

VOA’s Ihsan M. Khan contributed to this article.
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Snakebites are classified as a neglected tropical disease by the World Health Organization. In South Africa and other countries in the region, there are numerous barriers to getting the antivenom necessary to save limbs and lives. But scientists are working to make antivenom cheaper, safer and easier to produce. Kate Bartlett reports from Johannesburg. Camera: Zaheer Cassim
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The naturally occurring form of polio remains active in only two countries in the world: Pakistan and Afghanistan. Over 50 cases of so-called wild polio have been confirmed in the region this year despite continuing efforts to eradicate the disease. This report comes from both sides of the border, narrated by Bezhan Hamdard.
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One person died and dozens fell ill from E. coli infections linked to McDonald’s Quarter Pounder hamburgers in 10 states, led by Colorado, where 26 people were sickened, the U.S. Centers for Disease Control said on Tuesday.

The E. coli outbreak, linked to one of McDonald’s most popular menu items, has sickened 49 people and sent 10 to the hospital, officials say.

The strain involved, E. coli O157:H7, can cause serious illness and was the source of a 1993 outbreak that killed four children who ate undercooked hamburgers at Jack in the Box restaurants.

Shares of the world’s largest fast-food chain were down about 6% in extended trading. A livestock trader said the outbreak also could pressure U.S. cattle futures on Wednesday by threatening demand for beef.

Everyone interviewed as part of an investigation into the outbreak has reported eating at McDonald’s before their illness started, and most mentioned eating a Quarter Pounder hamburger, according to the CDC.

The specific ingredient linked to the illness has not been identified but investigators are focused on fresh, slivered onions and fresh beef patties, the CDC said.

Most of the illnesses were reported in Colorado and Nebraska.

“The initial findings from the investigation indicate that a subset of illnesses may be linked to slivered onions used in the Quarter Pounder and sourced by a single supplier that serves three distribution centers,” McDonald’s North America Chief Supply Chain Officer Cesar Piña said in a statement.

McDonald’s has proactively removed the slivered onions and beef patties used for the Quarter Pounder hamburgers from stores in the affected states while the investigation continues, the company informed the CDC.

U.S. food safety attorney Bill Marler, who represented a victim in the Jack in the Box outbreak, said more cases of illness could surface. Onions have been linked to prior E. coli O157:H7 outbreaks, he said.

According to Marler, a founder of Marler Clark in Seattle, beef contamination is less common due to food safety measures. “You’d have to have multiple restaurants under-cooking the meat,” he said.

McDonald’s is temporarily removing the Quarter Pounder from restaurants in the impacted areas, including Colorado, Kansas, Utah and Wyoming, it said in a statement, adding it was working with suppliers to replenish supply in the coming week.

Symptoms for E. coli include severe stomach cramps, diarrhea and vomiting. Most people who suffer an infection will start feeling sick three to four days after eating or drinking something that contains the bacteria, Colorado’s public health department said. However, illnesses can start anywhere from one to 10 days after exposure, the department added.

In 2015, burrito chain Chipotle saw its sales battered and reputation hit due to E.coli outbreaks in several states. That outbreak was linked to a different strain of E. coli that typically causes less severe illness than E. coli O157:H7.

In addition to Colorado, the CDC said small clusters of a few people fell ill after eating a Quarter Pounder in Nebraska, Utah and Wyoming. Kansas, Missouri, Oregon, Iowa, Wisconsin and Montana had one illness apiece.
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Health officials say there have been six cases of polio reported in Ivory Coast in 2023, and one so far this year. It doesn’t seem like many, but any polio cases are cause for concern among health officials trying to completely eradicate the disease.  VOA’s Yassin Ciyow reports from Abidjan, in this story narrated by Anthony LaBruto. (Camera: Yassin Ciyow )
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Berlin — An infection with the new mpox variant clade 1b has been detected in Germany for the first time, the Robert Koch Institute health authority said on Tuesday.  

The infection occurred abroad and was detected last Friday, the institute said, adding that it did not see an increased risk for Germany but was “monitoring the situation very closely.”  

Mpox, a viral disease related to smallpox that causes fever, body aches, swollen lymph nodes and a rash that forms into blisters, has two main subtypes — clade 1 and clade 2.  

From May 2022, clade 2 spread around the world, mostly affecting gay and bisexual men in Europe and the United States. In July 2022, the WHO declared an international public health emergency, its highest level of alarm over the spread.  

Vaccination and awareness drives in many countries helped stem the number of worldwide cases and the WHO lifted the emergency in May 2023 after reporting 140 deaths out of roughly 87,400 cases.  

But this year, a new epidemic has broken out in the Democratic Republic of Congo.  

As well as clade 1, which mainly affects children, a new strain emerged in the DRC, called clade 1b.  

Clade 1b cases have also been recorded in nearby Burundi, Kenya, Rwanda and Uganda — none of which had previously detected mpox. The WHO declared another international emergency in August.
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HONG KONG — China’s National Health Commission (NHC) published its first set of guidelines to standardize the diagnosis and treatment of obesity, with more than half of China’s adults already overweight and obese, and the rate expected to keep rising.

The guidelines, made public on October 17, come as China experiences an upward morbidity trend of its overweight and obese population. The rate of overweight or obese people could reach 65.3% by 2030, the NHC said.

“Obesity has become a major public health issue in China, ranking as the sixth leading risk factor for death and disability in the country,” the guidelines said.

China is facing a twin challenge that feeds its weight problem: In a modernizing economy underpinned by technological innovation, more jobs have become static or desk-bound, while a prolonged slowdown in growth is forcing people to adopt cheaper, unhealthy diets.

Job stress, long work hours and poor diets are growing high-risk factors in the cities, while in rural areas, agriculture work is becoming less physically demanding and inadequate healthcare is leading to poor screening and treatment of weight problems, doctors and academics say.

The guidelines provide guidance and regulations including in clinical nutrition, surgical treatment, behavioral and psychological intervention, and exercise intervention for obesity, Zhang Zhongtao, director of the guideline drafting committee and deputy head of Beijing Friendship Hospital, told the official Xinhua news agency.

China’s NHC and 15 other government departments in July launched public awareness efforts to fight obesity. The campaign, set to last for three years, is built around eight slogans: “lifelong commitment, active monitoring, a balanced diet, physical activity, good sleep, reasonable targets and family action.”

Health guidelines were distributed to primary and secondary schools in July urging regular screening, daily exercise, hiring nutritionists and implementing healthy eating habits – including lowering salt, oil and sugar.

Obesity in China is an “unintended consequence of improving living standards in the country,” Xinhua said, after China struggled for centuries to feed its population and under-nourishment was a genuine concern for many families before the reform and opening-up in the late 1970s.
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Paris — French drugmaker Sanofi’s confirmation that it will sell a controlling stake in its consumer health unit to a U.S. investment fund sparked a new political backlash Monday, stoked by fears the deal marks a loss of sovereignty over key medications.  

Paris “must block the sale” using powers to protect strategic sectors, Manuel Bompard, a senior lawmaker in the hard-left France Unbowed (LFI) party, told the TF1 broadcaster.  

Politicians and unions have torn into Sanofi’s proposed 16-billion-euro ($17.4 billion) deal with U.S. investment fund CD&R for a controlling stake in Opella.  

The subsidiary makes household-name drugs including Doliprane branded paracetamol  whose yellow boxes dominate the French market.  

Under pressure, Prime Minister Michel Barnier’s minority government said it had secured a two-percent stake in Opella for public investment bank Bpifrance and “extremely strong” guarantees against job cuts and offshoring.  

Opella employs over 11,000 workers and operates in 100 countries.  

Sanofi said it is the third-largest business worldwide in the market for over-the-counter medicines, vitamins and supplements.  

CD&R — which has a battery of investments in France — would help build Opella into a “French-headquartered, global consumer healthcare champion,” the pharma giant said in a statement.  

‘Just words’

But with memories of drug shortages during and since the Covid-19 pandemic still raw for many, critics say the defenses are too weak.

A small stake “won’t give the French state a say in strategic decisions” at Opella, said Bompard, whose LFI dominates a left alliance that is the largest opposition group against Barnier and President Emmanuel Macron.  

Thomas Portes, also of the LFI, posted on X that the government had offered “no guarantees, just words.”  

Economy Minister Antoine Armand said a contract between CD&R, Sanofi and the government included maintaining production sites, research and development and Opella’s official headquarters in France, as well as investing at least 70 million euros over five years.  

It covers “keeping up a minimum production volume for Opella’s sensitive products in France,” Armand added, including Doliprane, digestive medication Lanzor and Aspegic branded aspirin.  

There would be financial penalties for closing French production sites, laying off workers or failing to buy from French suppliers.  

That includes Seqens, a company re-establishing production in France of Doliprane’s active ingredient paracetamol.  

“Workers are not at all reassured by the latest developments,” said Johann Nicolas, a CGT union representative at Opella’s Doliprane plant in Lisieux, northern France.  

He added that a picket had throttled production there from around 1.3 million boxes of the drug per day to around 265,000.  

The proposed protections in the deal have also failed to win over even some in the government camp.  

Monday’s guarantees “do not at all indicate a commitment for the long term, whether on investment, supply or jobs,” Charles Rodwell, a lawmaker in Macron’s EPR party who has closely followed the case, told AFP.  

He vowed “painstaking” parliamentary surveillance of government action over the deal including measures to “block” the sale if ministers fall short.

Brand loyalty

Macron said last week that “the government has the instruments needed to protect France” from any unwanted “capital ownership.”  

Emotion over the Opella sales is closely linked to Doliprane.  

Boxes of the non-opioid analgesic against mild to moderate pain and fever often line entire pharmacy walls.  

The drug comes in many doses — from 100 mg for babies to 1,000 mg for adults — and in tablet, capsule, suppository and liquid forms.  

It is so ubiquitous that French people call any paracetamol product Doliprane, even when made by a different manufacturer.  

Sanofi, among the world’s top 12 health care companies, says the planned spinoff is part of a strategy to focus less on over-the-counter medication and more on innovative medicines and vaccines, including for polio, influenza and meningitis.
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Bogota, Colombia — Global environmental leaders gather Monday in Cali, Colombia to assess the world’s plummeting biodiversity levels and commitments by countries to protect plants, animals and critical habitats.

The two-week United Nations Biodiversity Conference, or COP16, is a follow-up to the 2022 Montreal meetings where 196 countries signed a historic global treaty to protect biodiversity.

The accord includes 23 measures to halt and reverse nature loss, including putting 30% of the planet and 30% of degraded ecosystems under protection by 2030.

In opening remarks on Sunday, Colombia’s environment minister and COP16 president Susana Muhamad said the conference is an opportunity “to collect the experience that has passed through this planet from all civilizations, from all cultures, from all knowledge … to generate livable, relatively stable conditions for a new society that will be forged in the light of the crisis.”

A real threat to biodiversity loss

All evidence shows a dramatic decline in species abundance and distribution, said Linda Krueger, director of biodiversity at The Nature Conservancy.

“A lot of wild species have less room to live, and they’re declining in numbers,” Krueger said. “And we also see rising extinction rates. Things that we haven’t even discovered yet are blinking out.”

The world is experiencing its largest loss of life since the dinosaurs, with around 1 million plant and animal species now threatened with extinction, according to the United Nations Environment Programme.

In the Amazon rainforest, threats to biodiversity include the expansion of the agricultural frontier and road networks, deforestation, forest fires and drought, says Andrew Miller, advocacy director at Amazon Watch, an organization that protects the rainforest.

“You put all of that together and it’s a real threat to biodiversity,” Miller said.

Global wildlife populations have plunged on average by 73% in 50 years, according to the WWF and the Zoological Society of London biennial Living Planet report this month.

The report said Latin America and the Caribbean saw 95% average declines in recorded wildlife populations.

Indigenous communities key to biodiversity protection

Indigenous people are on the front lines of protecting biodiversity and fighting against climate change, putting their lives at great risk, said Miller of Amazon Watch.

“A lot of discourse has been given about the voices of local communities … Indigenous peoples really playing a key role,” he said. “So that’s one of the things that we’ll be looking for at COP16.”

Indigenous peoples hold the solutions to combat the climate change and biodiversity crises, said Laura Rico, campaign director at Avaaz, a global activism nonprofit.

“They’re who have been taking care of the land, healing the land through their governance systems, their care systems and their ways of life,” she said. “So … it’s fundamental that the COP recognizes, promotes and encourages the legalization of their territories.”

In Colombia’s capital, Bogota, the head of an Amazon Indigenous organization said the region’s Indigenous people have been preparing for months for COP16.

“This is a great opportunity to make the impact that we need to demonstrate to all the actors that come from other countries the importance of Indigenous peoples for the world,” said José Mendez, secretary of the National Organization of the Indigenous Peoples of the Amazon.

“It’s no secret to anyone that we … are at risk right now,” he said. “The effects that we are currently experiencing due to climate change, the droughts that the country is experiencing, the Amazon River has never gone through a drought like the current one. … This is causing many species to become extinct.”

Nature can recover

Environment minister Muhamad told local media this month that one of the conference’s main objectives is to deliver the message that “biodiversity is as important, complementary and indispensable as the energy transition and decarbonization.”

Part of Colombia’s first ever leftist government, Muhamad cautioned last year’s World Economic Forum about the risks of continuing an extractive economy that ignores the social and environmental consequences of natural resource exploitation.

Since the 2022 Montreal conference, “progress has been too slow”, says Eva Zabey, executive director of the coalition Business for Nature.

“There’s been some progress,” she said. “But the headline message is the implementation of the global biodiversity framework is too slow and we need to scale and speed up.”

“COP16 comes at an absolutely critical moment for us to move from targets setting to real actions on the ground,” Zabey said.

Although biodiversity declines are grim, some environmentalists believe a reversal is possible. “We’ve had some very successful species reintroductions and we’ve saved species when we really focus on what is causing their decline,” said The Nature Conservancy’s Krueger.
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Geneva — The WHO chief on Sunday urged Rwanda to keep up its fightback against Marburg, as the country battles an outbreak of one of the world’s deadliest viruses.  

There have been 62 confirmed cases and 15 deaths in the outbreak, which was first announced in late September.  

No new cases have been detected in the last six days and 44 people have recovered from infection.  

Tedros Adhanom Ghebreyesus, the head of the World Health Organization, visited Rwanda to see the outbreak response for himself and hailed the country’s handling of the situation.  

“We’re pleased to see that there have been no new cases in the past six days, and we hope that remains the case,” he told a press conference in the capital Kigali.  

“But we are dealing with one of the world’s most dangerous viruses, and continued vigilance is essential.  

“Enhanced surveillance, contact tracing and infection prevention and control measures must continue at scale until the outbreak is declared over.”  

Such a declaration can only be made after 42 days — two consecutive incubation periods — without a new confirmed case.  

Marburg is transmitted to humans from fruit bats, and is part of the filovirus family that includes Ebola.  

With a fatality rate of up to 88 percent, Marburg’s highly infectious hemorrhagic fever is often accompanied by bleeding and organ failure.   

However, the case fatality rate in this outbreak has been held down at 24 percent.   

On Saturday, Tedros visited the treatment center where the remaining patients are being looked after.  

“Two of the patients we met had experienced all of the symptoms of Marburg, including multiple organ failure, but they were put on life support, they were successfully intubated and extubated, and are now recovering,” he said.  

“We believe this is the first time patients with Marburg virus have been extubated in Africa. These patients would have died in previous outbreaks.”  

There are currently no officially approved vaccines nor approved antiviral treatments, but potential treatments, including blood products, immune and drug therapies are being evaluated.  

A vaccination program using a trial vaccine was launched in Rwanda earlier this month. 
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MILWAUKEE — Whooping cough is at its highest level in a decade for this time of year, U.S. health officials reported Thursday.

There have been 18,506 cases of whooping cough reported so far, the Centers for Disease Control and Prevention said. That’s the most at this point in the year since 2014, when cases topped 21,800.

The increase is not unexpected — whooping cough peaks every three to five years, health experts said. And the numbers indicate a return to levels before the coronavirus pandemic, when whooping cough and other contagious illnesses plummeted.

Still, the tally has some state health officials concerned, including those in Wisconsin, where there have been about 1,000 cases so far this year, compared to a total of 51 last year.

Nationwide, CDC has reported that kindergarten vaccination rates dipped last year and vaccine exemptions are at an all-time high. Thursday, it released state figures, showing that about 86% of kindergartners in Wisconsin got the whooping cough vaccine, compared to more than 92% nationally.

Whooping cough, also called pertussis, usually starts out like a cold, with a runny nose and other common symptoms, before turning into a prolonged cough. It is treated with antibiotics. Whooping cough used to be very common until a vaccine was introduced in the 1950s, which is now part of routine childhood vaccinations. It is in a shot along with tetanus and diphtheria vaccines. The combo shot is recommended for adults every 10 years.

“They used to call it the 100-day cough because it literally lasts for 100 days,” said Joyce Knestrick, a family nurse practitioner in Wheeling, West Virginia.

Whooping cough is usually seen mostly in infants and young children, who can develop serious complications. That’s why the vaccine is recommended during pregnancy, to pass along protection to the newborn, and for those who spend a lot of time with infants.

But public health workers say outbreaks this year are hitting older kids and teens. In Pennsylvania, most outbreaks have been in middle school, high school and college settings, an official said. Nearly all the cases in Douglas County, Nebraska, are schoolkids and teens, said Justin Frederick, deputy director of the health department.

That includes his own teenage daughter.

“It’s a horrible disease. She still wakes up — after being treated with her antibiotics — in a panic because she’s coughing so much she can’t breathe,” he said.

It’s important to get tested and treated with antibiotics early, said Dr. Kris Bryant, who specializes in pediatric infectious diseases at Norton Children’s in Louisville, Kentucky. People exposed to the bacteria can also take antibiotics to stop the spread.

“Pertussis is worth preventing,” Bryant said. “The good news is that we have safe and effective vaccines.”
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People with HIV can safely receive donated kidneys from deceased donors with the virus, according to a large study that comes as the U.S. government moves to expand the practice. That could shorten the wait for organs for all, regardless of HIV status.

The new study, published Wednesday in the New England Journal of Medicine, looked at 198 kidney transplants performed across the U.S. Researchers found similar results whether the donated organ came from a person with or without the AIDS virus.

Last month, the Department of Health and Human Services proposed a rule change that would allow these types of kidney and liver transplants outside research studies. A final rule would apply to both living and deceased donors. If approved, it could take effect in the coming year.

Participants in the study were HIV positive, had kidney failure and agreed to receive an organ from either an HIV-positive deceased donor or an HIV-negative deceased donor, whichever kidney became available first.

Similar survival rates

Researchers followed the organ recipients for up to four years. They compared the half who received kidneys from HIV-positive donors to those whose kidneys came from donors without HIV.

Both groups had similarly high rates of overall survival and low rates of organ rejection. Virus levels rose for 13 patients in the HIV donor group and for four in the other group, mostly tied to patients failing to take HIV medications consistently, and in all cases returned to very low or undetectable levels.

“This demonstrates the safety and the fantastic outcomes that we’re seeing from these transplants,” said study co-author Dr. Dorry Segev of NYU Langone Health.

In 2010, surgeons in South Africa provided the first evidence that using HIV-positive donor organs was safe in people with HIV. But the practice wasn’t allowed in the United States until 2013 when the government lifted a ban and allowed research studies, at the urging of Segev. At first, the studies were with deceased donors. Then in 2019, Segev and others at Johns Hopkins University in Baltimore performed the world’s first kidney transplant from a living donor with HIV to an HIV-positive recipient.

All told, 500 transplants of kidneys and livers from HIV-positive donors have been done in the U.S.

‘A win-win’

People with HIV have been actively discouraged from signing up to be organ donors by stigma and outdated state laws and policies criminalizing organ donation for people with HIV, said Carrie Foote, a sociology professor at Indiana University in Indianapolis.

“Not only can we help those of us living with this disease, but we free up more organs in the entire organ pool so that those who don’t have HIV can get an organ faster,” said Foote, who is HIV positive and a registered organ donor. “It’s a win-win for everyone.”

More than 90,000 people are on the waiting list for kidney transplants, according to the U.S. Organ Procurement and Transplantation Network. In 2022, more than 4,000 people died waiting for kidneys.

In an editorial in the journal, Dr. Elmi Muller of Stellenbosch University in South Africa predicted the new study will have “far-reaching effects in many countries that do not perform transplantations with these organs.”

“Above all, we have taken yet another step toward fairness and equality for persons living with HIV,” wrote Muller, who pioneered the practice.
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ISLAMABAD — Pakistan said Saturday that two children in its southern Sindh province had been paralyzed by poliovirus, bringing the total number of cases nationwide to 39 for the year since March, when officials confirmed the first case.

The South Asian nation of around 240 million people reported six cases of paralytic poliovirus infections in 2023, following a period of more than a year without any documented cases, only to see the numbers rise again.

“Genetic sequencing of the cases is under way,” said a Pakistan polio eradication program statement Saturday while reporting the two new infections in Sindh. “The intense virus transmission and increase in polio cases are indicative of the harm that children suffer when they miss opportunities for vaccination.”

Pakistan and neighboring Afghanistan, with at least 20 cases this year, are the only two countries where the crippling disease is still endemic.

Pakistani officials are preparing to launch a nationwide vaccination campaign on October 28 to immunize more than 45 million children under 5 against the paralytic disease.

“It is critical for parents to open their doors to vaccinators during this drive and ensure that all children in their care receive two drops of the crucial oral polio vaccine to keep them protected from the devastating effects of polio,” the program emphasized in its Saturday statement.

Pakistan’s southwestern Balochistan province, which sits on the Afghan border, has reported 20 polio cases in 2024, while Sindh has detected 12 cases.

The Khyber Pakhtunkhwa province bordering Afghanistan has documented five paralytic poliovirus cases. Pakistan’s most populous Punjab province and the national capital, Islamabad, reported one case each.

The resurgence of poliovirus in Pakistan is blamed on boycotts of vaccination drives by parents in rural areas who allege the initiatives are a Western plot to sterilize Muslim children.

Anti-state militants in violence-hit districts bordering Afghanistan occasionally attack vaccinators and their police escorts, suspecting them of spying for the government. The violence has claimed the lives of dozens of security forces and vaccinators.

An independent monitoring board of the Global Polio Eradication Initiative noted in a report last month that more than 420,000 Pakistani children could not be inoculated in anti-polio campaigns in 2024.

The board reported more than 200 boycotts of the polio vaccination campaign in Khyber Pakhtunkhwa last year. “It is disturbing to realize that violence, insecurity, and boycotts are still as prevalent in Khyber Pakhtunkhwa as they were in 2023,” the report said.

It highlighted that residents in several impoverished districts of Pakistan also demanded electricity, gas supply, and road construction in return for getting their children vaccinated.

A representative for Pakistan’s Ministry of Health told a World Health Organization meeting in Doha, Qatar, earlier this week that polio eradication is the country’s “top priority,” and efforts have been intensified to halt virus transmission.

“Despite recent resurgence, a unified plan with provinces aims to stop polio transmission by 2025,” Safi Malik stated. “We’re focusing on quality campaigns, digital tracking of missed areas, and a strong Pakistan-Afghanistan collaboration for cross-border vaccinations,” he said. 
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