Researchers in the United States have shown for the first time they can safely and effectively infect human volunteers with Zika virus, a step toward learning more about the disease and developing vaccines and treatments.  

The study – known as a “controlled human infection model” – has previously been controversial for Zika because of the risks to participants and lack of treatments. 

But U.S. regulators and the World Health Organization ruled the new model, developed by a team at the Johns Hopkins Bloomberg School of Public Health, was safe and scientifically important.  

Zika is a viral infection spread by mosquitoes, which is usually mild or asymptomatic. 

But a major outbreak in the Americas in 2015 and 2016 showed it can be dangerous for pregnant women and fetuses, causing devastating birth defects such as microcephaly, a disorder in which a child is born with an abnormally small head and brain.  

There are no vaccines or treatments, and the outbreak in the Americas ended before new ones could be fully tested. Infections have dwindled worldwide since, with about 40,000 reported last year from that region. 

But the WHO has warned that surveillance can be patchy, and transmission patterns for Zika are not well understood. Climate change is also likely to boost the spread, which is already established in 91 countries. 

Anna Durbin, the Johns Hopkins professor who led the study, said developing countermeasures was essential because infections could re-surge. 

Also significant, she added, was the mental health burden on pregnant women in endemic regions, who worry about the virus and their babies — but have limited protection options.  

Durbin and her colleagues used two strains of Zika to infect 20 female volunteers who were not pregnant or lactating. All developed laboratory-confirmed infections, with mild illness. Eight others got a placebo.  

To minimize the risks, the patients were admitted to an inpatient unit and monitored until they were free of the virus. They agreed to use birth control methods for two months.  

The next step is evaluating the strains in male volunteers, in part to assess how long the virus, which can be sexually transmitted, stays infectious in semen.  

Durbin said several vaccine manufacturers have already asked to use the strains to test experimental products.  

The data was presented as an abstract at the annual meeting of the American Society of Tropical Medicine and Hygiene in Chicago.  
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The World Health Organization warns that tens of thousands of survivors of a series of powerful 6.3 magnitude earthquakes that struck western Afghanistan’s Herat province between October 7 and 15 are in desperate need of humanitarian aid and essential health services.

“I have personally seen how these multiple earthquakes flattened villages, displaced thousands of people and left many families in urgent need of humanitarian and health assistance,” said Alaa AbouZeid, health emergencies team lead for WHO Afghanistan.

Speaking in Kabul on Friday, AbouZeid said, “Over 114,000 people are in urgent need of lifesaving health assistance. … The health consequences are staggering.”

Those most seriously affected by the disaster, he said, are women, girls, boys and the elderly, “who account for over 90% of the deaths and injuries. Many children are left orphaned.”

The Office for the Coordination of Humanitarian Affairs, or OCHA, reports that the earthquakes directly affected more than 66,000 people — about 1,500 killed, some 2,000 injured, at least 3,700 homes destroyed and another 21,300 buildings damaged.

“I have talked to people affected by earthquakes, and the sense of loss is heartbreaking,” said Luo Dapeng, WHO representative in Afghanistan. “Many people spent days digging under the rubble to search for members who either died or got injured.”

According to an initial assessment by the WHO, at least 40 health facilities across nine districts were damaged, resulting in severe disruptions of health services for an estimated 580,000 people.

AbouZeid said health providers were afraid to go into those buildings, which showed visible cracks and risked collapse. “So, most health services for now are provided from tents,” he said, calling the situation untenable.

“We need immediate action to restore, renovate and ensure services that provide health facilities, especially in wintertime. The survivors need water [and] better shelters that can protect them from the harsh winter,” he said.

“Last year, Herat experienced minus 30 degrees centigrade during wintertime, and winter has already started in Afghanistan,” he said. “So, there are needs for water and sanitation to stop any possible disease outbreaks.”

He said that WHO staff in Afghanistan was on the ground within hours of the disaster and able to treat the injured, provide medicine and medical supplies, and give mental health and trauma care.

“Thanks to the long and established presence in Herat, we were able to rapidly mobilize resources … and extend immediate lifesaving support to the affected population at the most critical time of the emergency.”

He said the WHO has deployed 21 female health workers, including doctors and midwives, to Herat to ensure that women have unimpeded access to the health services they need.

“They have been distributed over different facilities to provide services for their female patients, with a special focus on reproductive health services, obstetrics, gynecology services and child health services,” AbouZeid said.

The WHO launched an appeal for $7.9 million Wednesday to provide urgent and essential health services for 114,000 of the most vulnerable people in the next six months.

AbouZeid said the WHO needs to scale up emergency health needs urgently and swiftly “as the upcoming winter season is bringing new health risks and exposure to the affected population currently living outdoors or in tents.”
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India successfully carried out Saturday the first of a series of key test flights after overcoming a technical glitch ahead of its planned mission to take astronauts into space by 2025, the space agency said.

The test involved launching a module to outer space and bringing it back to earth to test the spacecraft’s crew escape system, said the Indian Space Research Organization chief S. Somanath, and was being recovered after its touchdown in the Bay of Bengal.

The launch was delayed by 45 minutes in the morning because of weather conditions. The attempt was again deferred by more than an hour because of an issue with the engine, and the ground computer put the module’s liftoff on hold, said Somanath.

The glitch caused by a monitoring anomaly in the system was rectified and the test was carried out successfully 75 minutes later from the Sriharikota satellite launching station in southern India, Somanath told reporters.

It would pave the way for other unmanned missions, including sending a robot into space next year.

In September, India successfully launched its first space mission to study the sun, less than two weeks after a successful uncrewed landing near the south pole region of the moon.

After a failed attempt to land on the moon in 2019, India in September joined the United States, the Soviet Union and China as only the fourth country to achieve the milestone.

The successful mission showcased India’s rising standing as a technology and space powerhouse and dovetails with Prime Minister Narendra Modi’s desire to project an image of an ascendant country asserting its place among the global elite.

Signaling a roadmap for India’s future space ambitions, Modi earlier this week announced that India’s space agency will set up an Indian-crafted space station by 2035 and land an Indian astronaut on the moon by 2040.

Active since the 1960s, India has launched satellites for itself and other countries, and successfully put one in orbit around Mars in 2014. India is planning its first mission to the International Space Station next year in collaboration with the United States.
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It’s been a month since a Maryland man became the second person to receive a transplanted heart from a pig — and hospital video released Friday shows he’s working hard to recover.

Lawrence Faucette was dying from heart failure and ineligible for a traditional heart transplant because of other health problems when doctors at the University of Maryland School of Medicine offered the highly experimental surgery.

In the first glimpse of Faucette provided since the September 20 transplant, hospital video shows physical therapist Chris Wells urging him to smile while pushing through a pedaling exercise to regain his strength. 

“That’s going to be tough, but I’ll work it out,” Faucette, 58, replied, breathing heavily but giving a smile. 

The Maryland team last year performed the world’s first transplant of a heart from a genetically altered pig into another dying man. David Bennett survived just two months before that heart failed, for reasons that aren’t completely clear, although signs of a pig virus later were found inside the organ. Lessons from that first experiment led to changes before this second try, including better virus testing. 

Attempts at animal-to-human organ transplants — called xenotransplants — have failed for decades, as people’s immune systems immediately destroyed the foreign tissue. Now scientists are trying again using pigs genetically modified to make their organs more humanlike. 

In Friday’s hospital video, Faucette’s doctors said the pig heart has shown no sign of rejection. 

“His heart is doing everything on its own,” said Dr. Muhammad Mohiuddin, the Maryland team’s cardiac xenotransplantation chief. 

A hospital spokesperson said Faucette, of Frederick, Maryland, has been able to stand and physical therapists are helping him gain the strength needed to attempt walking. 

Many scientists hope xenotransplants one day could compensate for the huge shortage of human organ donations. More than 100,000 people are on the nation’s list for transplants, most awaiting kidneys, and thousands will die waiting. 

A handful of scientific teams have tested pig kidneys and hearts in monkeys and in donated human bodies, hoping to learn enough for the Food and Drug Administration to allow formal xenotransplant studies. 
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Astronomers have detected an intense flash of radio waves coming from what looks like a merger of galaxies dating to about 8 billion years ago — the oldest-known instance of a phenomenon called a fast radio burst that continues to defy explanation. 

This burst in less than a millisecond unleashed the amount of energy our sun emits in three decades, researchers said. It was detected using the Australian SKA Pathfinder, a radio telescope in the state of Western Australia. Its location was pinpointed by the European Southern Observatory’s Very Large Telescope in Chile, one of the most powerful optical telescopes. 

A fast radio burst, or FRB, is a pulse of radio-frequency electromagnetic radiation. It lasts a small fraction of a second but outshines most other sources of radio waves in the universe. Radio waves have the longest wavelengths in the electromagnetic spectrum. 

“The radio waves in FRBs are similar to those used in microwave ovens. The amount of energy in this FRB is the equivalent to microwaving a bowl of popcorn twice the size of the sun,” said astronomer Ryan Shannon of Swinburne University of Technology in Australia, co-leader of the study published this week in the journal Science. 

Until now, the oldest known such burst dated to 5 billion years ago, making this one 3 billion years older. The universe is about 13.8 billion years old. For comparison, Earth is about 4.5 billion years old. In seeing objects and events from long ago, astronomers peer across vast cosmic distances, making this burst also the farthest of any FRB ever detected. 

“We now know that fast radio bursts have been around for more than half the age of the universe,” said astronomer and study co-leader Stuart Ryder of Macquarie University in Australia. 

Fast radio bursts were discovered in 2007. 

“The most likely source is a hypermagnetized neutron star, called a magnetar. These stars are stellar corpses the mass of the sun but only the size of a small city. They are some of the most extreme objects in the universe, which you would need to produce such extreme bursts,” Shannon said. 

“There are more energetic events in the universe, associated with stellar explosions or a black hole shredding a star apart. But FRBs are unique in that they produce all their energy in radio waves, with nothing seen in other bands — optical light or X-rays, for example — and that the signals are so short,” Shannon added. 

They also are more common, Shannon added, with upward of 100,000 thought to occur somewhere in the universe daily. Far fewer have been detected, Shannon said, and only around 50 — including this one — have been traced back to the galaxy where they originated. 

“Galaxies in the distant universe look different than those nearby — they don’t have nice spiral arms — so it wasn’t clear if what we were seeing was one galaxy with a few clumps, or a few smaller galaxies. It is likely that the source is a few galaxies, possibly merging,” Shannon said. 

The researchers said that studying these bursts also can help to detect and measure the immense amount of matter believed to populate the expanses of space between galaxies. As these radio waves zip though the cosmos, they can flag the presence of this intergalactic plasma — gas so hot that some or all its atoms are split into the subatomic particles electrons and ions. 

“Most of the normal matter in the universe — this is the regular matter that makes up stars, planets, humans — is thought to reside in a diffuse cosmic web of gas between galaxies,” Shannon said. “People have been searching for this matter for decades using other techniques. Because it is so diffuse, it is nearly invisible in any other way, so [it] was considered ‘missing.'”
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With warmer oceans serving as fuel, Atlantic hurricanes are now more than twice as likely as before to rapidly intensify from wimpy minor hurricanes to powerful and catastrophic, a study said Thursday.

Last month Hurricane Lee went from barely a hurricane at 129 kph to the most powerful Category 5 hurricane with 249 kph winds in 24 hours. In 2017, before it devastated Puerto Rico, Hurricane Maria went from a Category 1 storm with 145 kph to a top-of-the-chart whopper with 257 kph winds in just 15 hours.

The study looked at 830 Atlantic tropical cyclones since 1971. It found that in the last 20 years, 8.1% of the time storms powered from a Category 1 minor storm to a major hurricane in just 24 hours. That happened only 3.2% of the time from 1971-90, according to a study in the journal Scientific Reports. Category 1 hurricanes top out at 153 kph and a hurricane has to have at least 178 kph winds to become major.

Those are the most extreme cases, but the fact that the rate of such turbocharging has more than doubled is disturbing, said study author Andra Garner, a climate scientist at Rowan University in New Jersey.

When storms rapidly intensify, especially as they near land, it makes it difficult for people in the storm’s path to decide on what they should do — evacuate or hunker down. It also makes it harder for meteorologists to predict how bad it will be and for emergency managers to prepare, Garner and other scientists said.

“We know that our strongest, most damaging storms very often do intensify very quickly at some point in their lifetimes,” Garner said, highlighting 2017’s Maria, which some researchers said killed nearly 3,000 people directly and indirectly. “We’re talking about something that’s hard to predict that certainly can lead to a more destructive storm.”

And this “has become more common in the last 50 years,” Garner said. “This has all happened over a time period when we’ve seen ocean waters get warmer.”

“We’ve had 90% of the excess warming that humans have caused to the planet going into our oceans,” Garner said.

Oceans this year have been setting heat records monthly since April with scientists warning of off-the-charts temperatures.

Garner found the rapid intensification of hurricanes was primarily along the East Coast’s Atlantic seaboard, more so than the Gulf of Mexico.

It’s not just the cases of extreme rapid intensification. Garner looked at all storms over different time periods and found that in general they’re intensifying faster than they used to.

There have been more Atlantic storms in the last few decades than in the 1970s and 1980s – scientists have several theories for why, from changes in air pollution to natural cycles – but Garner said by looking at percentages she took out the storm frequency factor.

Previous studies had found an increase in rapid intensification. Garner’s study was statistically meticulous in confirming what scientists had figured, said Karthik Balaguru, a Pacific Northwest National Lab climate scientist who last year had a paper demonstrating how storms near the Atlantic coast are intensifying faster before landfall than they did in the 1970s and 1980s.

The National Hurricane Center considers a storm to rapidly intensify if it increases wind speed by 46 kph in 24 hours.

In 2020, a record year for hurricanes and the last year of Garner’s study, six storms rapidly intensified that much. Hannah, Laura, Sally, Teddy, Gamma and Delta. Since then, there have been several rapid intensifying and deadly storms, including 2021’s Ida, 2022’s Ian and 2023’s Idalia.

“If we don’t work to lower our (carbon) emissions, then that’s a trend that we likely could expect to see continue to happen in the future” and even get worse, Garner said.
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Burkina Faso’s health ministry has declared a dengue fever epidemic amid the deadliest outbreak in years. More than 200 people have died, and new cases are rising sharply.

There have been 50,478 suspected cases and 214 deaths of the mosquito-borne illness this year, the ministry said in a statement released on Wednesday, mostly in the urban centers of the capital, Ouagadougou, and Bobo Dioulasso. It said about 20% of the cases and deaths were recorded last week alone.

Dengue kills an estimated 20,000 people worldwide each year. Rates of the disease have risen eightfold since 2000, driven largely by climate change, the increased movement of people and urbanization.

The World Health Organization this month warned that the disease would become a major threat in new parts of Africa as warmer temperatures create conditions for the mosquitoes carrying the infection to spread.

Dengue is spread by infected Aedes aegypti mosquitoes. Symptoms include fever, muscle pain, nausea and rashes. Lack of treatment or misdiagnosis, common in poverty-stricken countries such as Burkina Faso where health care is spotty, increase the chance of death.

Burkina Faso’s outbreak dwarfs other African outbreaks in recent years. According to figures from the Africa Centers for Disease Control and Prevention, dengue killed 18 people in Burkina Faso in 2017 and 15 in 2016.

The health ministry said that it was providing free rapid diagnostic tests and had organized spraying of insecticide in public places to counter the spread.
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Australian researchers say they have produced the most comprehensive view of the history of the universe to date. An Australian National University team says their study offers new ideas about how the universe might have started.

The research team says the study’s aim was to understand the origins of all the objects in the universe.

The U.S. space agency, NASA, says the universe “includes all of space, and all the matter and energy that space contains. It even includes time itself and, of course, it includes you.”

NASA adds that “the Milky Way is but one of billions of galaxies in the observable universe — all of them, including our own, are thought to have supermassive black holes at their centers.”

The Australian team says it has created the most comprehensive chart ever created of the history of the universe.

The lead author is honorary associate professor Charley Lineweaver. He said that when the universe began 13.8 billion years ago in a hot big bang, there were no objects, such as protons, atoms, people, planets, stars or galaxies.

The authors say the charts provide new ideas about how the universe came into being.

The first shows temperature and density of the universe as it expanded and cooled. The second plots the mass and size of all objects in the universe. The ANU researchers say the study suggests the universe may have started as what is known as an instanton, which has a specific size and mass, rather than a singularity, which they say is a hypothetical point of infinite density and temperature. Put simply, this would mean that at its beginning the universe may have been finite, and not infinite, in size. This is important because researchers say that what lies beyond the boundary of the universe is “also a major mystery.”

Lineweaver told VOA that mapping the universe will boost our understanding of it.

“When you extrapolate in so many different ways it gives you just a lay of the land that I just think is a beautiful way of understanding the universe,” he said. “If there is one way to understand the Big Bang it started out hot and dense and it got cooler and less dense, and as it did that particles and objects of all kinds condensed out of this hot, dense background. And understanding that is something that we should all make an attempt to do that because that is probably the most profound underlying theme of the history of the universe.”

Lineweaver also said he believes that research into the origins of the universe could help to answer some fundamental scientific questions about life beyond Earth.

“How did we get here? So, I am kind of semi-obsessed with the big picture of life on Earth and what it means and whether we are alone or not and so I have been writing quite a few things about that,” he said. “The basic idea is, well, if we can figure out how we got here, maybe we can make better guesses about whether other life forms have evolved elsewhere.”

The Australian National University study is published in the latest issue of The American Journal of Physics. 
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U.N. inspectors took samples from a fish market near the Fukushima nuclear power plant on Thursday following the release of wastewater from the wrecked facility in August.

China and Russia have banned Japanese seafood imports since the discharge began but Japan says it is safe, a view backed so far by the International Atomic Energy Agency (IAEA).

Some 540 Olympic swimming pools worth of water have been collected since a tsunami sent three reactors at Fukushima-Daiichi into meltdown in 2011 in one of the world’s worst nuclear disasters.

Japan says that the water has been filtered by its special ALPS technology of radioactive substances — except tritium — and diluted with seawater.

Japan says tests have shown that tritium levels are within safe limits.

The IAEA team comprising scientists from China, South Korea and Canada were collecting fish, water and sediment samples this week to verify Japan’s findings.

Paul McGinnity, a member of the mission, told reporters that the aim was “to ascertain whether the Japanese labs are measuring and analyzing properly” tritium levels.

“Tritium is the concern because tritium levels as you know are relatively high because it is not removed by the ALPS process,” McGinnity said.

“I can say that we don’t expect to see any change (in tritium levels), certainly in the fish. We do expect to see a small rise in levels of tritium in seawater samples very close to the discharge point. But otherwise, we don’t. We expect to find levels that are very similar to what we measured last year.”

Samples will be sent back to labs in the team members’ home countries for independent review, and the IAEA will evaluate and publish those results.

Russia this week followed its ally China in banning Japanese seafood imports, although it buys relatively small volumes.

Japan, which has called China’s ban politically motivated, said Moscow’s move was an “unjust” step “without any scientific basis.”

The water release is aimed at making space to begin removing the highly dangerous radioactive fuel and rubble from the wrecked reactors.
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As the war drags on, some severely injured Ukrainians who received medical help abroad are returning home. Yana Stepanenko and her mother have resettled in Lviv after a year of treatment and rehabilitation in the U.S. Omelyan Oshchudlyak has the story. Camera: Yuriy  Dankevych      
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A clinical trial is recruiting thousands of volunteers — including a large number of Black women who face disparities in breast cancer death rates — to try to find out.

People like Carole Stovall, a psychologist in Washington, D.C., have signed up for the study to help answer the question.

“We all need a mammogram anyway, so why not do it with a study that allows the scientists to understand more and move closer to finding better treatments and ways of maybe even preventing it?” Stovall said.

The underrepresentation of women and minorities in research is a long-simmering issue affecting health problems including Alzheimer’s disease, stroke and COVID-19. Trials without diversity lead to gaps in understanding of how new treatments work for all people.

“Until we get more Black women into clinical trials, we can’t change the science. And we need better science for Black bodies,” said Ricki Fairley, a breast cancer survivor and advocate who is working on the issue.

Black women are 40% more likely to die from breast cancer than white women and tend to be diagnosed younger. But it’s not clear whether 3D mammography is better for them, said Dr. Worta McCaskill-Stevens of the National Cancer Institute.

“Are there populations for whom this might be important to have early diagnosis?” asked McCaskill-Stevens. “Or is it harmful,” causing too many false alarms or unneeded follow-up tests and treatments?

McCaskill-Stevens, who is Black, leads NCI’s efforts to boost access to cancer research in minority and rural communities. She has joined the study herself.

The newer 3D technique has been around for a decade, but there’s never been conclusive evidence that it’s better than 2D at detecting advanced cancers. The screening technique combines multiple pictures of the breast taken from different angles to create a 3D-like image. Both 3D and 2D mammograms compress the breast and use low doses of radiation.

Prior studies suggest that 3D finds more cancers than 2D, but catching more cancers doesn’t necessarily mean more lives saved. Some cancers missed by standard screening may not progress or need treatment. Previous studies did not randomly assign patients to a screening method, the gold standard for research.

The notion “that if it’s new, it’s shiny, then it’s better,” isn’t necessarily true, McCaskill-Stevens said. “Until we have the evidence to support that, then we need well-designed randomized trials.”

The trial has enrolled nearly 93,000 women so far with a goal of 128,000. The NCI-funded study is now running in Canada, South Korea, Peru, Argentina, Italy and 32 U.S. states. A site in Thailand will soon begin enrolling patients.

“We added more international sites to enhance the trial’s diversity, particularly for Hispanic and Asian women,” said Dr. Etta Pisano, who leads the study.

Overall, 42% of participants are Hispanic. As recruiting continues, enrolling Black women and other women of color will “absolutely” continue as a priority, Pisano said.

Participants are randomly assigned to either 2D or 3D mammograms and are followed for several years. The number of advanced cancers detected by the two methods will be compared.

At the U.S. study sites, 21% of study participants are Black women — that’s higher than a typical cancer treatment study, in which 9% of participants are Black, McCaskill-Stevens said.

The University of North Carolina has signed up more Black women than any other study site. Nearly a quarter of the nearly 3,000 women enrolled at UNC’s two locations are Black.

“Women in North Carolina want to take part in something that’s bigger than them,” said Dr. Cherie Kuzmiak, who leads the UNC arm of the study. “They want this active role in helping determine the future of health care for women.”

In Washington, D.C., word of mouth has led to successful recruiting.

A chance encounter at her hair salon persuaded Stovall to join the research. While waiting for a hair appointment, she met Georgetown University cancer researcher Lucile Adams-Campbell. The two, both Black, started chatting.

“She explained how important it was to get women of color into the program,” said Stovall, who jumped at the chance to catch up on her mammograms after the COVID-19 pandemic delayed screening for her and thousands of others.

For Stovall, there was a personal reason to join the research. Her sister recently completed treatment for triple negative breast cancer, an aggressive type that affects Black women at higher rates than white women.

Women ages 45 to 74 without a personal history of breast cancer are eligible for the study, which launched in 2017. Many women also are providing blood and cheek swab samples for a database that will be mined for insights.

“It’s a dream that people had since the beginning of screening that we wouldn’t fit everybody into the same box,” Pisano said. The study’s findings could “reduce disparities if we’re successful, assuming people have access to care.”

Stovall, 72, had a brief scare when her mammogram, the traditional 2D type, showed something suspicious. A biopsy ruled out cancer.

“I was extremely relieved,” Stovall said. “Everybody I know has heard from me about the need for them to go get a mammogram.”
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Four-day work weeks improved Spanish workers’ health several ways, such as by lowering stress while reducing fuel emissions and benefiting children, a pilot program showed on Tuesday. 

The coastal city of Valencia — Spain’s third largest with more than 800,000 inhabitants — scheduled local holidays to fall on four consecutive Mondays between April 10 and May 7 this year. The project affected 360,000 workers. 

Many participants used the long weekends to develop healthier habits such as practicing sport, resting and eating homemade food, according to an independent commission of health and social science experts that evaluated the program. 

The data showed an improvement in self-perceived health status, lower stress levels and better feelings regarding tiredness, happiness, mood and personal satisfaction, it added. 

A drop in the use of motor vehicles led to better air quality on the four Mondays during the program’s period, as less nitrogen dioxide was emitted, according to the city’s daily emissions measurements. 

However, smokers and drinkers increased their overall use of tobacco and alcohol, it said.

More time for hobbies, leisure

A high percentage of those surveyed said they were more likely to read, study, watch films and pursue hobbies such as  photography, music or painting, the commission said. It did not specify the percentage. 

Children benefited the most, thanks to improved work-life balance enjoyed by their parents, the commission found. 

Retail sales down

While the hospitality and tourism sectors served more customers during extended weekends, retailers reported a decrease in sales and emergency medical services may have been overextended as more healthcare workers took time off, the report said. 

The project was designed by the left-wing Compromis coalition of progressive, green and regionalist parties, which ruled the city at the time. 

Last year, the Spanish government launched a similar two-year project focused on small and medium-sized industrial companies nationwide. 
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