Month: January 2023

‘M3gan’ Dolls Up With $30.2 Million While ‘Avatar’ Stays No. 1

The Blumhouse evil-doll horror film “M3gan” got off to a killer start, debuting with $30.2 million in ticket sales, according to studio estimates, while “Avatar: The Way of Water” continued its box-office reign in the top spot. 

Universal Pictures’ “M3gan,” about a robot companion built for a young girl after her parents are killed in a car accident, rode strong buzz and viral dancing memes to an above-expectations debut. In the low-budget slasher, starring Allison Williams, Blumhouse and producer James Wan crafted Hollywood’s first hit of the new year, likely spawning a new high-concept horror franchise. 

Audiences gave the PG-13 film a “B” CinemaScore — though reviews (94% fresh on Rotten Tomatoes) were stronger for the modern, techy twist on a “Child’s Play”-like thriller. It added $10 million internationally. 

But while “M3gan” drew audiences largely in 2D showings, large-format screens continued to be soaked up by James Cameron’s “Avatar: The Way of Water.” The 3-D three-hour sequel remained No. 1 for the fourth straight week in U.S. and Canadian theaters with $45 million in sales. 

Cameron’s sci-fi spectacle has now surpassed $500 million domestically and $1.7 billion globally. After dominating the otherwise lackluster holiday corridor, the “Avatar” sequel is nearly matching the original’s pace; the 2009 “Avatar” scored $50.3 million in its fourth weekend. “The Way of Water” already ranks as the seventh highest grossing film ever, not accounting for inflation — a total particularly owed to its strong overseas performance. The film’s $1.2 billion in international ticket sales exceeds that of any film released since the start of the pandemic. 

“M3gan” was the only new film in wide release, though Sony Pictures’ “A Man Called Otto,” starring Tom Hanks, played in 637 theaters after first launching in four theaters. The film, a remake of the Swedish film “A Man Called Ove,” managed a solid $4.2 million ahead of its nationwide release on Friday. 

Third place went to “Puss in Boots: The Last Wish,” with $13.1 million in its third week of release. The animated Universal Pictures sequel has tallied $87.7 million in three weeks, plus $109.7 million internationally. 

While many awards contenders have struggled in recent months at the box office, Darren Aronofsky’s “The Whale” is proving a modest exception. The A24 indie starring Brendan Fraser ranked seventh in its fifth week of release with $1.5 million and a cumulative total of $8.6 million — a good return for a film that cost an estimated $3 million to make. 

Estimated ticket sales for Friday through Sunday at U.S. and Canadian theaters, according to Comscore. Final domestic figures will be released Monday. 

"Avatar: The Way of Water," $45 million. 
"M3gan," $30.2 million. 
"Puss in Boots: The Last Wish," $13.1 million. 
"A Man Called Otto," $4.2 million. 
"Black Panther: Wakanda Forever," $4 million. 
"Whitney Houston: I Wanna Dance With Somebody," $2.4 million. 
"The Whale," $1.5 million. 
"Babylon," $1.4 million. 
"Violent Night," $740,000. 
"The Menu," $713,000. 

Paxlovid Not on ‘Approved Drug List’ for China’s Health Insurance

China will not include Pfizer Inc’s Paxlovid in an update to its list of medicines covered by basic medical insurance schemes as the U.S. firm quoted a high price for the COVID-19 drug, China’s Healthcare Security Administration (NHSA) said Sunday.   

The COVID-19 antiviral drug is currently covered by the country’s broad health care insurance scheme under temporary measures the regulator introduced in March last year as outbreaks rose.   

But authorities held talks with Pfizer in recent days to decide whether to include it in the latest version of their list, which they update annually.   

Inclusion on the list means a drug is accessible via state insurance schemes, which will boost volumes but comes with the condition that manufacturers lower prices. Past rounds have seen drugmakers cut prices by as much as 62% after negotiations with officials.   

“We will continue to collaborate with the Chinese government and all relevant stakeholders to secure an adequate supply of Paxlovid in China. We remain committed to fulfilling the COVID-19 treatment needs of Chinese patients,” Pfizer said in a statement, without elaborating.   

The NHSA said Paxlovid would continue to be eligible to be paid for by state medical insurance until the current planned end-date to the temporary measures of March 31.   

While the talks on Paxlovid failed, they succeeded with two other COVID-19 treatment drugs — herbal medication Qingfei Paidu granules and Chinese drugmaker Genuine Biotech’s Azvudine — which will be included in the list’s update, the regulator said.   

Three years into the pandemic, China began pivoting away from its signature “zero COVID” policy last month after historic protests of the economically-damaging curbs that had been championed by President Xi Jinping.   

The sudden loosening of restrictions has fueled a giant wave of infections and prompted many to turn to underground channels to procure remedies such as Paxlovid, which a clinical trial has found to have reduced hospitalizations in high-risk patients by around 90%.   

Boxes of Paxlovid are changing hands for as much as 50,000 yuan ($7,313.15), more than 20 times the original price of 2,300 yuan, according to local media reports and social media posts.   

Beijing has been largely resistant to Western vaccines but has greenlighted foreign oral treatments Paxlovid and Merck’s Molnupiravir. It approved Paxlovid in February.   

Reuters reported Saturday, citing sources, that China is in talks with Pfizer to secure a license that will allow domestic drugmakers to manufacture and distribute a generic version of Paxlovid.   

Last month, China Meheco Group Co Ltd said Wednesday it signed an agreement with Pfizer to import and distribute Paxlovid in mainland China.   

Pfizer also signed a deal in August for Chinese drugmaker Zhejiang Huahai to produce Paxlovid in mainland China solely for patients there. 

Seattle Schools Sue Tech Giants Over Social Media Harm

The public school district in Seattle has filed a novel lawsuit against the tech giants behind TikTok, Instagram, Facebook, YouTube and Snapchat, seeking to hold them accountable for the mental health crisis among youth.

Seattle Public Schools filed the lawsuit Friday in U.S. District Court. The 91-page complaint says the social media companies have created a public nuisance by targeting their products to children.

It blames them for worsening mental health and behavioral disorders including anxiety, depression, disordered eating and cyberbullying; making it more difficult to educate students; and forcing schools to take steps such as hiring additional mental health professionals, developing lesson plans about the effects of social media and providing additional training to teachers.

“Defendants have successfully exploited the vulnerable brains of youth, hooking tens of millions of students across the country into positive feedback loops of excessive use and abuse of Defendants’ social media platforms,” the complaint said. “Worse, the content Defendants curate and direct to youth is too often harmful and exploitive ….”

While federal law — Section 230 of the Communications Decency Act — helps protect online companies from liability arising from what third-party users post on their platforms, the lawsuit argues that provision does not protect the tech giants’ behavior in this case.

“Plaintiff is not alleging Defendants are liable for what third-parties have said on Defendants’ platforms but, rather, for Defendants’ own conduct,” the lawsuit said. “Defendants affirmatively recommend and promote harmful content to youth, such as pro-anorexia and eating disorder content.”

In emailed statements Sunday, Google and Snap said they had worked to protect young people who use their platforms.

Snap launched an in-app support system called ‘Here For You’ in 2020, to help those who might be having a mental health or emotional crisis find expert resources, and it also has enabled settings that allow parents to see whom their children contact on Snapchat, though not the content of those messages. It also has recently expanded content about the new 988 suicide and crisis phone system in the U.S.

“We will continue working to make sure our platform is safe and to give Snapchatters dealing with mental health issues resources to help them deal with the challenges facing young people today,” the company said in a written statement.

José Castañeda, a spokesperson for Google, said Google, which owns YouTube, had also given parents the ability to set reminders, limit screen time and block certain types of content on their children’s devices.

“We have invested heavily in creating safe experiences for children across our platforms and have introduced strong protections and dedicated features to prioritize their well-being,” Castañeda said.

Meta and TikTok did not immediately respond to requests for comment.

The lawsuit says that from 2009 to 2019, there was on average a 30% increase in the number of Seattle Public Schools students who reported feeling “so sad or hopeless almost every day for two weeks or more in a row” that they stopped doing some typical activities.

The school district is asking the court to order the companies to stop creating a public nuisance, to award damages, and to pay for prevention education and treatment for excessive and problematic use of social media.

While hundreds of families are pursuing lawsuits against the companies over the harm they allege their children suffered from social media, it’s not clear if any other school districts have filed a complaint like Seattle’s.

Internal studies revealed by Facebook whistleblower Frances Haugen in 2021 showed that the company knew that Instagram negatively affected teenagers by harming their body image and making eating disorders and thoughts of suicide worse. She alleged that the platform prioritized profits over safety and hid its own research from investors and the public.

CES 2023: Smelling, Touching Take Center Stage in Metaverse 

Is the metaverse closer than we think?

It depends on whom you ask at CES, where companies are showing off innovations that could immerse us deeper into virtual reality, otherwise known as VR.

The metaverse — essentially a buzzword for three-dimensional virtual communities where people can meet, work and play — was a key theme during the four-day tech gathering in Las Vegas that ends Sunday.

Taiwanese tech giant HTC unveiled a high-end VR headset that aims to compete with market leader Meta, and a slew of other companies and startups touted augmented reality glasses and sensory technologies that can help users feel — and even smell — in a virtual environment.

Among them, Vermont-based OVR Technology showcased a headset containing a cartridge with eight primary aromas that can be combined to create different scents. It’s scheduled to be released later this year.

An earlier, business-focused version used primarily for marketing fragrances and beauty products is integrated into VR goggles and allows users to smell anything from a romantic bed of roses to a marshmallow roasting over a fire at a campsite.

The company says it aims to help consumers relax and is marketing the product, which comes with an app, as a sort of digital spa mixed with Instagram.

“We are entering an era in which extended reality will drive commerce, entertainment, education, social connection, and wellbeing,” the company’s CEO and co-founder Aaron Wisniewski said in a statement. “The quality of these experiences will be measured by how immersive and emotionally engaging they are. Scent imbues them with an unmatched power.”

But more robust and immersive uses of scent — and its close cousin, taste — are still further away on the innovation spectrum. Experts say even VR technologies that are more accessible are in the early days of their development and too expensive for many consumers to purchase.

The numbers show there’s waning interest. According to the research firm NPD Group, sales of VR headsets, which found popular use in gaming, declined by 2% last year, a sour note for companies betting big on more adoption.

Still, big companies like Microsoft and Meta are investing billions. And many others are joining the race to grab some market share in supporting technologies, including wearables that replicate touch.

Customers, though, aren’t always impressed by what they find. Ozan Ozaskinli, a tech consultant who traveled more than 29 hours from Istanbul to attend CES, suited up with yellow gloves and a black vest to test out a so-called haptics product, which relays sensations through buzzes and vibrations and stimulates our sense of touch.

Ozaskinli was attempting to punch in a code on a keypad that allowed him to pull a lever and unlock a box containing a shiny gemstone. But the experience was mostly a letdown.

“I think that’s far from reality right now,” Ozaskinli said. “But if I was considering it to replace Zoom meetings, why not? At least you can feel something.”

Proponents say widespread adoption of virtual reality will ultimately benefit different parts of society by essentially unlocking the ability to be with anyone, anywhere at any time. Though it’s too early to know what these technologies can do once they fully mature, companies looking to achieve the most immersive experiences for users are welcoming them with open arms.

Aurora Townsend, the chief marketing officer at Flare, a company slated to launch a VR dating app called Planet Theta next month, said her team is building its app to incorporate more sensations like touch once the technology becomes more widely available on the consumer market.

“Being able to feel the ground when you’re walking with your partner, or holding their hands while you’re doing that… subtle ways we engage people will change once haptic technology is fully immersive in VR,” Townsend said.

Still, it’s unlikely that many of these products will become widely used in the next few years, even in gaming, said Matthew Ball, a metaverse expert. Instead, he said the pioneers of adoption are likely to be fields that have higher budgets and more precise needs, such as bomb units using haptics and virtual reality to help with their work and others in the medical field.

In 2021, Johns Hopkins neurosurgeons said they used augmented reality to perform spinal fusion surgery and remove a cancerous tumor from a patient’s spine.

And optical technology from Lumus, an Israeli company that makes AR glasses, is already being used by underwater welders, fighter pilots and surgeons who want to monitor a patient’s vital signs or MRI scans during a procedure without having to look up at several screens, said David Goldman, vice president of marketing for the company.

Meanwhile, Xander, a Boston-based startup which makes smart glasses that display real-time captions of in-person conversations for people with hearing loss, will launch a pilot program with the U.S. Department of Veterans Affairs next month to test out some of its technology, said Alex Westner, the company’s co-founder and CEO. He said the agency will allow veterans who have appointments for hearing loss or other audio issues to try out the glasses in some of their clinics. And if it goes well, the agency would likely become a customer, Westner said.

Elsewhere, big companies from Walmart to Nike have been launching different initiatives in virtual reality. But it’s not clear how much they can benefit during the early stages of the technology. The consulting firm McKinsey says the metaverse could generate up to $5 trillion by 2030. But outside of gaming, much of today’s VR use remains somewhat of a marginal amusement, said Michael Kleeman, a tech strategist and visiting scholar at the University of California San Diego.

“When people are promoting this, what they have to answer is — where’s the value in this? Where’s the profit? Not what’s fun, what’s cute and what’s interesting.”

For more coverage of CES, visit: https://apnews.com/hub/technology

Thailand Introduces New Entry Regulations as China Reopens Border

Thailand will require international travelers to show proof they are fully vaccinated for COVID before flying to Thailand, according to the country’s aviation regulator, as it prepares for more tourists after China reopened its border on Sunday.

The Civil Aviation Authority of Thailand said in a statement Saturday that starting early Monday, all foreign arrivals starting early on Monday must prove they are vaccinated or provide a letter certifying that they have recovered from COVID within six months.

Unvaccinated travelers must show a medical certificate explaining why they have not received the vaccine.

CAAT said airlines would be responsible for checking documents before passengers board and has released a list of how many doses are required for various types of COVID-19 vaccines on its website.

The new measure will remain in effect at least until the end of January, CAAT said.

The vaccination requirement was scrapped by Thailand last October but has been revived as China reopens its border following the easing of its zero-COVID policy.

The first commercial flight from China to Thailand, Xiamen Airlines flight MF833, will arrive to Bangkok from Xiamen on Monday carrying 286 passengers, government spokeswoman Traisuree Taisaranakul said Sunday.

Foreigners traveling to Thailand from a country where a negative reverse transcription polymerase chain reaction test result is a condition for entry are required to show proof of health insurance that covers COVID-19 treatment, the Health Ministry said.

The new entry requirements do not apply to Thai passport holders or passengers transiting through Thailand.

China Ends Quarantine for Overseas Travelers

China lifted quarantine requirements for inbound travelers Sunday, ending almost three years of self-imposed isolation even as the country battles a surge in COVID cases.

The first people to arrive expressed relief at not having to undergo the grueling quarantines that were a fixture of life in zero-COVID China.

And in Hong Kong, where the border with mainland China was reopened after years of closure, more than 400,000 people were set to travel north in the coming eight weeks.

Beijing last month began a dramatic dismantling of a hardline zero-COVID strategy that had enforced mandatory quarantines and punishing lockdowns.

The policy had a huge impact on the world’s second-biggest economy and generated resentment throughout society that led to nationwide protests just before it was eased.

At Shanghai’s Pudong International Airport, a woman surnamed Pang told AFP on Sunday she was thrilled with the ease of travel.

“I think it’s really good that the policy has changed now, it’s really humane,” she told AFP.

“It’s a necessary step, I think. COVID has become normalized now and after this hurdle everything will be smooth,” she said.

Chinese people rushed to plan trips abroad after officials last month announced that quarantine would be dropped, sending inquiries on popular travel websites soaring.

But the expected surge in visitors has led more than a dozen countries to impose mandatory COVID tests on travelers from the world’s most populous nation as it battles its worst-ever outbreak.

China has called travel curbs imposed by other countries “unacceptable,” despite it continuing to largely block foreign tourists and international students from travelling to the country.

China’s COVID outbreak is forecast to worsen as it enters the Lunar New Year holiday this month, during which millions are expected to travel from hard-hit megacities to the countryside to visit vulnerable older relatives.

And Beijing has moved to curb criticism of its chaotic path out of zero-COVID, with its Twitter-like Weibo service saying it had recently banned 1,120 accounts for “offenses against experts and scholars.”

‘We just walked out’

At Beijing airport Sunday, barriers that once kept international and domestic arrivals apart were gone, as were the “big whites” — staff in hazmat suits long a fixture of life in zero-COVID China.

One woman, there to greet a friend arriving from Hong Kong, said the first thing they’d do was grab a meal.

“It’s so great, we haven’t seen each other in so long,” Wu, 20, told AFP.

“They are studying over there, and we can meet each other directly in Beijing … It’s been a year,” she added.

At Shanghai airport, one man surnamed Yang who was arriving from the United States said he had not been aware that the rules had changed.

“I had no idea,” he told AFP.

“I’d consider myself extremely lucky if I only need to do quarantine for two days, turned out I don’t have to do quarantine at all, and no paperwork, we just walked out like that, exactly like in the past,” he added.

“I’m quite happy not needing to be in quarantine,” another woman being picked up by her boyfriend who declined to give her name told AFP.

“Who wants to be in quarantine? Nobody.”

Hong Kong opens

In China’s southern semiautonomous city of Hong Kong, visitors streamed across the border as travel restrictions with the Chinese mainland were eased.

Hong Kong’s recession-hit economy is desperate to reconnect with its biggest source of growth, and families are looking forward to reunions over the Lunar New Year.

Official data showed some 410,000 people in Hong Kong planned to travel north in the next two month, while some 7,000 people in the mainland planned to travel south Sunday.

At the Lok Ma Chau checkpoint near Shenzhen, a postgraduate student from mainland China surnamed Zeng told AFP they were happy to cross with no more restrictions.

“I am happy as long as I don’t have to be quarantined — it was so unbearable,” Zeng told AFP.

Ukrainian Startups Bring Tech Innovation to CES 2023

The past year has been difficult for startups everywhere, but running a company in Ukraine during the Russian invasion comes with a whole different set of challenges.

Clinical psychologist Ivan Osadchyy brought his medical device, called Knopka, to this year’s consumer technology show known as CES in Las Vegas in hopes of getting it into U.S. hospitals.

His is one of a dozen Ukrainian startups backed by a government fund that are at CES this year to show their technology to the world.

“Two of our hospitals we operated before are ruined already and one is still occupied. So this is the biggest challenge,” Osadchyy said.

“The second challenge is for production and our team because they are shelling our electricity system and people are hard to work without lights, without heating in their flats,” he said.

Inspired by grandmother

He came up with the device after spending a year with his own grandmother in the hospital and finding that he had to track down nurses when she needed something.

The system works by notifying nurses when a patient has an abnormal heart rate, is due for treatment or otherwise needs help. The nurse can’t turn off their button until they’ve dealt with the issue.

“We are still working and operating because hospitals are open and we need to support them and provide efficiency and safety for patients as well,” he said.

Karina Kudriavtseva of the government-backed Ukrainian Startup Fund, says that, like Knopka, all the country’s startups have kept going since Russia’s invasion almost a year ago.

“The times have changed, their conditions have changed, but it can only make them stronger because all of the startups are working on the thing that to save the company, save the team, save the business, and save their lives, of course,” she said.

Conflict led to relocation, innovation

The invasion forced Valentyn Frechka to relocate to France, but he says his Releaf paper company has never stopped production.

When he was 16, Frechka decided to study alternative sources of cellulose in order to decrease deforestation. He’s now developed a technology that uses fallen leaves and recycled fiber to make paper.

The company’s main product is paper shopping bags, but they also make food packaging, egg trays and corrugated boxes.

Frechka said the conflict has forced the company to become more flexible and more open to opportunities.

“When this conflict happened and we located our company to France, we have found a lot of new partners and we have raised fundraising. We have raised the money for our needs,” he said. “So, it really makes us more open for the world.”

NASA Satellite Falling From the Sky Soon

A 38-year-old retired NASA satellite is about to fall from the sky.

NASA said Friday the chance of wreckage falling on anybody is “very low.” Most of the 5,400-pound (2,450-kilogram) satellite will burn up upon reentry, according to NASA. But some pieces are expected to survive.

The space agency put the odds of injury from falling debris at about 1-in-9,400.

The science satellite is expected to come down Sunday night, give or take 17 hours, according to the Defense Department.

The California-based Aerospace Corp., however, is targeting Monday morning, give or take 13 hours, along a track passing over Africa, Asia the Middle East and the westernmost areas of North and South America.

The Earth Radiation Budget Satellite, known as ERBS, was launched in 1984 aboard the space shuttle Challenger. Although its expected working lifetime was two years, the satellite kept making ozone and other atmospheric measurements until its retirement in 2005. The satellite studied how Earth absorbed and radiated energy from the sun.

The satellite got a special send-off from Challenger. America’s first woman in space, Sally Ride, released the satellite into orbit using the shuttle’s robot arm. That same mission also featured the first spacewalk by a U.S. woman: Kathryn Sullivan. It was the first time two female astronauts flew in space together.

It was the second and final spaceflight for Ride, who died in 2012.

US Approves Alzheimer’s Drug That Modestly Slows Disease

 U.S. health officials on Friday approved a closely watched Alzheimer’s drug that’s been shown to modestly slow the early stages of the brain-robbing disease, albeit with potential safety risks that doctors and patients will have to weigh carefully.

The drug, Leqembi, is the first that’s been convincingly shown to slow the decline in memory and thinking that defines Alzheimer’s by targeting the disease’s underlying biology. The Food and Drug Administration approved it specifically for patients with mild or early cases of dementia.

An uncommon success

Leqembi, from Japan’s Eisai and its U.S. partner Biogen, is a rare success in a field accustomed to failed experimental treatments for the incurable condition. The delay in cognitive decline brought about by the drug likely amounts to just several months, but some experts say it could still meaningfully improve people’s lives.

“This drug is not a cure. It doesn’t stop people from getting worse, but it does measurably slow the progression of the disease,” said Dr. Joy Snider, a neurologist at Washington University in St. Louis. “That might mean someone could have an extra six months to a year of being able to drive.”

Snider stressed that the medicine, pronounced “leh-KEM-bee,” comes with downsides, including the need for twice-a-month infusions and possible side effects such as brain swelling and bleeding.

Approval came via FDA’s accelerated pathway, which allows drugs to launch based on early results, before they’re confirmed to benefit patients. The agency’s use of that shortcut has come under increasing scrutiny from government watchdogs and congressional investigators.

Last week, a congressional report found that the FDA’s approval of a similar Alzheimer’s drug called Aduhelm — also from Biogen and Eisai — was “rife with irregularities,” including a number of meetings with drug company staffers that went undocumented.

Average price tag: $26,500 a year

Scrutiny of the new drug, known chemically as lecanemab, will likely mean most patients won’t start receiving it for months, as insurers decide whether to cover it and for whom.

The drug will cost $26,500 for a typical year’s worth of treatment. Eisai said that price reflects the drug’s benefit in terms of improved quality of life, reduced burdens for caregivers and other factors. The company pegged its overall value at $37,000 per year, but said it priced the drug lower to reduce costs for patients and insurers. An independent group that assesses drug value recently said the drug would have to be priced below $20,600 to be cost-effective.

Some 6 million people in the U.S. and many more worldwide have Alzheimer’s, which gradually attacks areas of the brain needed for memory, reasoning, communication and daily tasks.

The FDA’s approval was based on one mid-stage study in 850 people with early symptoms of Alzheimer’s who also tested positive for a type of brain plaque that is a hallmark of the disease.

Since then, Eisai has published the results of a larger 1,800-patient study that the FDA is expected to soon review to confirm the drug’s benefit, setting up a decision on full approval later this year.

The larger study tracked patients’ results on an 18-point scale that measures memory, judgment and other cognitive abilities. Doctors compile the rating from interviews with the patient and a close contact. After 18 months, patients receiving Leqembi declined more slowly — a difference of less than half a point on the scale — than patients who received a dummy infusion. The delay amounted to just over five months.

There is little consensus on whether that difference translates into real benefits for patients, such as greater independence.

“Most patients won’t notice the difference,” said Dr. Matthew Schrag, a neurology researcher at Vanderbilt University. “This is really quite a small effect and probably below the threshold of what we’d call clinically significant.”

Schrag and some other researchers believe a meaningful improvement would require at least a difference of one full point on the 18-point scale.

Leqembi works by clearing a sticky brain protein called amyloid that’s a key indicator of Alzheimer’s. But it’s not clear exactly what causes the disease. A string of other amyloid-targeting drugs have failed, and many researchers now think combination treatments will be needed.

Aduhelm, the similar drug, was marred by controversy over its effectiveness.

The FDA approved that drug in 2021 against the advice of the agency’s own outside experts. Doctors hesitated to prescribe the drug, and insurers restricted coverage.

The FDA did not consult the same expert panel before approving Leqembi.

Rep. Rosa DeLauro of Connecticut — a frequent FDA critic — said in a statement Friday that she was “deeply concerned that FDA chose to forego” a panel meeting on the drug.

Schrag said many of the same concerns apply to both drugs.

“Is this slight, measurable benefit worth the hefty price tag and the side effects patients may experience?” she asked. “I have pretty serious doubts.”

About 13% of patients in Eisai’s study had swelling of the brain and 17% had small brain bleeds, side effects seen with earlier amyloid-targeting medications. In most cases those problems didn’t cause symptoms, which can include dizziness and vision problems.

Also, several Leqembi users died while taking the drug, including two who were on blood-thinning medications. Eisai has said the deaths can’t be attributed to the drug. The FDA label warns doctors to use caution if they prescribe Leqembi to patients on blood thinners.

Insurers are likely to cover the drug only for people like those in the company study — patients with mild dementia and confirmation of amyloid buildup. That typically requires expensive brain scans or a spinal fluid test. Doctors will need to perform a different type of scan to periodically check for brain swelling and bleeding.

Medicare coverage still up in air

A key question in the drug’s rollout will be insurance coverage by Medicare, the federal health plan that covers 60 million seniors and other Americans. The agency severely restricted coverage of Aduhelm, essentially wiping out its U.S. market and prompting Biogen to abandon marketing plans for the drug.

Eisai executives said they have already spent months discussing their drug’s data with Medicare officials. Coverage isn’t expected until after the FDA confirms the drug’s benefit, expected later this year.

“Once we have a Medicare decision, then we can truly launch the drug across the country,” said Eisai’s U.S. CEO, Ivan Cheung.

Betsy Groves, 73, was diagnosed with Alzheimer’s in 2021. A former lecturer at Harvard’s graduate school of education, she noticed she was having trouble remembering some students’ names and answering questions.

Her initial diagnosis, based on a cognitive examination, was later confirmed by a positive test for amyloid.

Groves, of Cambridge, Massachusetts, says she is “more than willing” to try Leqembi, despite potential side effects and the need for infusions.

“For me, the minute that drug comes on the market — and I get my doctor’s approval — I’m going to take it,” Groves said.

Bills’ Hamlin Breathing on His Own, Joins Team Via Video

It was uplifting enough for the Buffalo Bills staff and players to see Damar Hamlin appear on the video screen in the team’s meeting room Friday — “larger than life,” as coach Sean McDermott put it — for the first time since the safety collapsed and had to be resuscitated on the field.

What sent everyone’s emotions over the top was hearing Hamlin, his mouth and throat still raw shortly after having a breathing tube removed, softly say: ” Love you, boys.”

“Amazing. Touching. To see Damar, No. 1, through my own eyes, I know it’s something I’ve been looking forward to, kind of needing to see,” McDermott said. “And to see the players’ reaction. They stood up right away and clapped for him and yelled some things at him. It was a pretty cool exchange.”

Four days since his heart stopped after making what appeared to be a routine tackle in a game, the 24-year-old Hamlin from his hospital room in Cincinnati and the Bills enjoyed a moment of jubilation in celebrating the next step in what his doctors have termed a remarkable recovery.

“We got our boy, man. It’s all that matters,” left tackle Dion Dawkins said.

“To see the boy’s face, to see him smile and to see him go like this in the camera,” Dawkins said, flexing his muscles to mimic Hamlin, “it was everything. And then to hear him talk, it was literally everything. That’s what we needed.”

Hamlin is now breathing and walking on his own and traded in the writing pad he had been using to communicate. Though there is no timetable for his release, Hamlin’s doctors said Thursday that both breathing on his own and showing continued signs of improvement are the final steps for him to be discharged from the University of Cincinnati Medical Center.

Hamlin spent his first two days in the hospital under sedation. Upon being awakened Wednesday evening, Hamlin was able to follow commands and grip people’s hands. The breathing tube was removed, the team said Friday, and Hamlin’s “neurologic function remains intact.”

The team did not say whether Hamlin’s status remains critical or whether he’s been moved from intensive care.

“The hair on the back of my neck stood up when he said, ‘I love you boys,'” said general manager Brandon Beane, who returned to Buffalo Thursday after spending the three days at Hamlin’s bedside along with the player’s family.

The turning point in Hamlin’s recovery, for Beane, anyway, came Thursday morning when the two exchanged hugs.

“Just to be able to hug him and the grip strength that he had,” Beane said, before recalling what he told Hamlin’s father, Mario. “I told him, I’m not a crier, but man it was emotional and a lot of grown men in there [were] crying yesterday. Something I’ll never forget.”

The sight of Hamlin collapsing, which was broadcast to a North American TV audience on ESPN’s “Monday Night Football,” has led to an outpouring of support from fans and players from across the league. Fans, team owners and players — including Tom Brady and Russell Wilson — have made donations to Hamlin’s Chasing M’s Foundation, which had raised just short of $8 million by Friday afternoon.

EPA Moves to Toughen Standards for Deadly Soot Pollution

The Biden administration is proposing tougher standards for a deadly air pollutant, saying that reducing soot from tailpipes, smokestacks and wildfires could prevent thousands of premature deaths a year. 

A proposal released Friday by the Environmental Protection Agency would set maximum levels of 9 to 10 micrograms of fine particle pollution per cubic meter of air, down from 12 micrograms set a decade ago under the Obama administration. The standard for particle pollution, more commonly known as soot, was left unchanged by former President Donald Trump, who overrode a scientific recommendation for a lower standard in his final days in office. 

Environmental and public health groups that have been pushing for a stronger standard were disappointed, saying the EPA proposal does not go far enough to limit emissions of what is broadly called “fine particulate matter,” the tiny bits of soot we breathe in unseen from tailpipes, wildfires, factory and power plant smokestacks, and other sources. 

In a development that could lead to an even lower standard, the EPA said Friday that it also would take comments on a range of ideas submitted by a scientific advisory committee, including a proposal that would lower the maximum standard for soot to 8 micrograms. A microgram is one-millionth of a gram. 

EPA Administrator Michael Regan said the proposal to strengthen the national ambient air quality standards for fine particle pollution would help prevent serious health problems, including asthma attacks, heart attacks and premature death that disproportionately affect vulnerable populations. Those populations include children, older adults and those with heart and lung conditions, as well as low-income and minority communities throughout the United States. 

“This administration is committed to working to ensure that all people, regardless of the color of their skin, the community they live in or the money in their pocket, have clean air to breathe, clean water to drink and the opportunity to lead a healthy life,” Regan said at a news conference. “At EPA, we are working every single day to create cleaner and healthier communities for all and have been doing so for over 50 years.” 

‘A disappointment’

Harold Wimmer, the president of the American Lung Association, called the EPA’s proposal disappointing, saying it was “inadequate to protect public health from this deadly pollutant.” 

“Current science shows that stronger limits are urgently needed … to protect vulnerable populations,” Wimmer said, calling for the EPA to lower the standard to 8 micrograms or lower. 

Seth Johnson, an attorney for the environmental group Earthjustice, called the EPA plan “a disappointment and missed opportunity overall.” While it would strengthen some public health protections, “EPA is not living up to the ambitions of this administration to follow the science, protect public health and advance environmental justice,” Johnson said. He urged the EPA “to hear communities, not industrial polluters, and strengthen this rule. Overburdened communities have the right to breathe clean air.” 

The U.S. Chamber of Commerce and other business groups called for the current standards to be maintained. 

“The United States has some of the best air quality in the world, thanks to steady reductions in contributors to particulate matter emissions over the last decade,” said Chad Whiteman, vice president of environment and regulatory affairs at the chamber’s Global Energy Institute. 

The proposed rule could “stifle manufacturing and industrial investment and exacerbate permitting challenges that continue to hamper the economy,” Whiteman said. 

‘Regulatory burden’

Mike Ireland, president of the Portland Cement Association, which represents U.S. cement manufacturers, added that the EPA’s proposed action “is yet another regulatory burden that will hamper the cement industry’s ability to manufacture sustainable construction materials to meet the nation’s infrastructure needs.” 

EPA scientists have estimated exposure at current limits causes the early deaths of thousands of Americans annually from heart disease and lung cancer as well as causing other health problems. 

Dr. Doris Browne, president of the National Medical Association, the oldest and largest national organization representing African American physicians, hailed the plan as “the bold action needed to protect public health across the country.” 

Appearing with Regan at a news conference, Browne said the proposal is likely to have lasting benefits across the country “but especially for those communities of color and low-income communities that experience the increase in particulate matter pollution.” Smog, soot and other pollution near factories, power plants and other hazards has a “devastating impact on public health,” she said. 

The EPA proposal would require states, counties and tribal governments to meet a stricter air quality standard for fine particulate matter up to 2.5 microns in diameter — far smaller than the diameter of a human hair. A micron, also called a micrometer, is equal to one-millionth of a meter. 

The standard would not force polluters to shut down, but the EPA and state regulators could use it as the basis for other rules that target pollution from specific sources such as diesel-fueled trucks, refineries and power plants. 

A 2022 report by the American Lung Association found that 63 million Americans live in counties that experience unhealthy daily spikes in soot pollution and 21 million live in counties that exceed annual limits for soot pollution. Most of those counties were in 11 Western states, the report said. People of color were 61% more likely than white people to live in a county with unhealthy air quality, the report said. 

Fresno, California, displaced Fairbanks, Alaska, as the metropolitan area with the worst short-term particle pollution, the report found, while Bakersfield, California, continued in the most-polluted slot for year-round particle pollution for the third year in a row. 

As of December 31, five metropolitan areas were not in compliance with current standards, the EPA said. Four of those areas are in California, including the San Joaquin Valley and Los Angeles. Allegheny County, Pennsylvania, which includes Pittsburgh, also is out of compliance. 

The EPA will accept comments on the proposed rule through mid-March and will hold a virtual public hearing over several days. A final rule is expected this summer.

India Makes $2.3 Billion Green Hydrogen Push to Meet Climate Goals

India has announced a $2.3 billion plan to promote “green hydrogen” — hydrogen produced with renewable energy — which experts say could be the clean fuel of the future.

The initiative could help the world’s third-largest emitter of greenhouse gases reach its goal of net zero carbon emissions by 2070. 

A series of incentives are aimed at making green hydrogen affordable by bringing down production costs of a technology that has yet to become commercially viable.  

While India has been rapidly expanding renewables such as solar energy, these will not be enough to meet climate goals in a country whose energy needs are expected to grow more than anywhere in the world over the next two decades. India’s current reliance on carbon-emitting coal, its primary source of electricity, has raised concerns on how it will switch to clean energy.

The government is hoping that investments under what is called the National Hydrogen Mission, will provide the answer.

“For lot of heavy industries like steel, cement and oil refining, green hydrogen can be a better solution to make them cleaner. Their massive energy requirements cannot be met by other renewable sources such as solar and wind,” Vibhuti Garg, South Asia director at the Institute for Energy Economics and Financial Analysis, said.

 “But much will depend on the cost economics” he said. 

Green hydrogen is made by using electricity from renewable sources to split hydrogen from water. The energy it produces creates no carbon emissions. But in an industry still in its infancy, the key lies in significantly lowering production costs. 

“The goal is to bring down its cost over the next five years,” Information and Broadcasting Minister Anurag Thakur said this week while announcing the initiative. He said it will also help India reduce its emissions and become a major exporter in the field.   

Some experts are optimistic. “In the last one year there has been a drop in green hydrogen prices from roughly $4 per kilogram to $3 now,” said Hemant Mallya at the Council for Energy, Environment and Water, a public policy think tank in New Delhi.

He said increased use will bring down costs further. “The eventual target is $1 per kilogram because that is when you start becoming competitive with coal. But even before that if we can hit $2 per kilogram, it will compete with gas currently imported from Russia and that is pretty much achievable with scale and technological advancement.”

The hope is that just as costs for solar power have dropped substantially in recent years and are now lower than that of electricity generated by coal plants, the cost of producing green hydrogen will also reduce over time. 

India’s goal is to produce 5 million tons of green hydrogen per year by 2030. Experts call it an “ambitious” target and point out that at the moment India only has a handful of pilot projects in the sector. 

However, India wants to ensure that it is not left behind in a technology that is now being looked at with much more hope as the world grapples with a climate crisis. In giving a push to green hydrogen, India is following other countries like the United States and those in the European Union that have also approved incentives worth billions of dollars for its development. 

“I think India does not want to miss the bus and is putting the building blocks in place,” said Garg. She pointed out that in the solar energy sector for example, China took the lead in manufacturing the most cost-competitive components for solar panels, leaving most countries, including India, dependent on Chinese imports. “In green hydrogen, India wants to be a pioneer and not wait for other countries to become the lead players.” 

As the government offers financial incentives, some of India’s biggest firms have made commitments to invest in green hydrogen. They include conglomerates like the Adani Group and Reliance Industries and state-owned energy companies.  

Still, experts say there are many challenges ahead in developing the nascent industry. India will have to scale up domestic manufacturing of electrolyzers, which are a key component to develop green hydrogen and also ensure that there is enough renewable energy available to make it. The investments needed will be huge. Domestic industries might have to be incentivized to switch to using green hydrogen.  

India is also eyeing exports of green hydrogen by becoming a cost-competitive source.

“Our aim is to establish India as a global hub of green hydrogen,” Thakur said. “We will make efforts to get at least 10% of the global demand for green hydrogen.” 

Hopes that export markets will emerge if green hydrogen becomes viable have risen after the disruption in global energy markets in the wake of Russia’s invasion of Ukraine. “We need to broaden the horizon and look at exports because the premium on the price of green hydrogen might be a problem domestically, but internationally it is not that much of a challenge for someone in Europe to pay it. And because of the Ukraine crisis for example, countries in Europe, will want to transition quicker than anticipated from natural gas,” according to Mallya.  

 

Historically Black US School Leaps Into College Gymnastics

Jordynn Cromartie entered her senior year of high school facing a daunting choice, one countless other Black gymnasts have faced for decades.

The teenager from Houston wanted to attend a historically Black college or university. And she wanted to compete in the sport she’s dedicated most of her life to.

One problem. She knew she couldn’t do both, something Cromartie brought up over Thanksgiving dinner while talking to her uncle, Frank Simmons, a member of the Board of Trustees at Fisk University, a private HBCU of around 1,000 students in Nashville, Tennessee.

“He and my aunt were like, ‘Oh you haven’t made a decision, you should come to Fisk,’” Cromartie said. “I’m like, ‘Well, they don’t have a gymnastics team.’ To go to a college that doesn’t have what I would be working for forever was crazy to me.”

Simmons, stunned, made a promise to his niece.

“Watch,” he told her. “I’ll make it happen.”

In the span of a few weeks, Simmons connected Derrin Moore — the founder of Atlanta-based Brown Girls Do Gymnastics, an organization that’d been trying to drum up support for an HBCU for years — with Fisk’s trustees. One trustee listened to Moore’s pitch and offered to make a $100,000 donation on the spot if Fisk adopted the sport.

And seemingly in a flash, all the roadblocks and misconceptions Moore had encountered while spending the better part of a decade trying to persuade an HBCU to take the leap on an increasingly diverse sport evaporated.

On Friday afternoon at Orleans Arena in Las Vegas, barely 14 months after Fisk committed to building a program from the ground up, Cromartie — now a freshman at her uncle’s alma mater — and the rest of her teammates will make history when they become the first HBCU to participate in an NCAA women’s gymnastics meet. The Bulldogs will compete against Southern Utah, North Carolina and Washington as part of the inaugural Super 16, an event that also includes perennial NCAA powers like Oklahoma, UCLA and Michigan.

“I feel like it’s nice to show that Black girls can do it, too,” Cromartie said. “We have a team that’s 100% of people of color and you’ve never seen that before anywhere. … I feel like we have a point to prove.”

The face of high-level women’s gymnastics is changing. While athletes of color have excelled at the sport’s highest level for decades, participation among Black athletes has spiked over the last 10 years thanks in part to the popularity of Olympic champions Gabby Douglas and Simone Biles.

Black gymnasts account for around 10% of scholarships at the NCAA Division I level, an increase from 7% in 2012, when Douglas became the first Black woman win to Olympic gold. More than 10% of USA Gymnastics members self-identify as Black.

It’s a massive jump from when Corrinne Tarver became the first Black woman to win an NCAA all-around title at Georgia in 1989.

“When I first went to school, there were a scattering of (Black gymnasts),” said Tarver, now the head coach and athletic director at Fisk. “One on this team, one on that team … there wasn’t a lot of African-American gymnasts around back then compared to today.”

Still, it caught Umme Salim-Beasley off guard when she began exploring her college options in the early 1990s. Salim-Beasley grew up in the Washington, D.C., area and competed in the same gym as four-time Olympic medalist Dominique Dawes. Salim-Beasley wanted to go to an HBCU. When she approached an HBCU recruiter at a college fair and told the recruiter she was a gymnast, the response she received shocked her.

“They didn’t see it as a sport for women of color,” said Salim-Beasley, who ended up competing at West Virginia and is now the head coach at Rutgers. “And that was the perception, that gymnastics was not a sport that was welcoming or had enough interest from women of color.”

Which has made the response to Fisk’s inaugural class even more rewarding.

For years, Moore and Salim-Beasley — a member of the advisory council at Brown Girls Do Gymnastics — would struggle just to set up exploratory interviews with HBCU athletics officials. In the months since Fisk’s program launched, Moore and Salim-Beasley have talked to presidents at nine HBCUs.

“People are really interested,” Moore said. “They still have a lot of questions and still not pulling the trigger, but they are reaching out.”

All of which puts Fisk in an enviable if challenging spot. The program is a beta test of sorts as other HBCUs watch from afar to see how Fisk handles the massive logistical and economic hurdles that come with launching a program.

The Bulldogs don’t have an on-campus facility and are currently training at a club gym a few miles from campus, though they are fundraising in hopes of remedying that soon. They are competing this year as an independent while waiting to get their NCAA status sorted out.

And Tarver immediately threw the program into the deep end of the pool. Their inaugural schedule includes meets at Michigan, Georgia and Rutgers.

“It would have been really easy to just put in schools that were not as strong and then make our whole schedule like that and then just hope for the best,” Tarver said. “But I didn’t want to do that. I wanted them to realize that they belong on that stage.”

In that way, Tarver is following through on her recruiting pitch last spring, when she spent hours on Zoom asking young women of color to believe in something that had never existed before.

“Basically, I pitched them on the dream,” Tarver said. “I told them they’ll be a part of history. Their names will go down in history as the first HBCU ever.”

It proved to be a far easier sell than Tarver imagined.

Morgan Price initially committed to Arkansas so she could compete with her older sister, Frankie. Yet once Fisk announced it was going to take the ambitious step of competing in 2023, Price felt drawn to the opportunity.

“Since we are the first, it’s kind of special,” Price said. “We get to build it from the ground up.”

And yes, the perks of being the first don’t hurt. Several Bulldogs appeared on Jennifer Hudson’s talk show in the fall. An Emmy-winning documentarian is following them throughout the season. The splash on social media has been sizable.

So has the splash in real life. When Price returned to her club gym in Texas shortly after committing to Fisk, the energy she felt from younger gymnasts of color as they peppered her with questions was palpable.

“They were telling me, ‘I can’t wait until I can be recruited so I can be an HBCU gymnast as well,’” Price said.

That’s the big-picture plan. Moore is optimistic several HBCU schools will follow in Fisk’s footsteps soon.

They just won’t be the first. That honor will go to the women in the blue-and-gold leotards who will salute the judges for the first time Friday, as the team filled with athletes who “come from backgrounds where they were kind of told that they weren’t as good,” as Tarver put it, makes history.

Athletes who no longer have to choose between heritage and opportunity.

“Already being an HBCU, we’re the underdogs,” Cromartie said. “We haven’t had much time to practice. We don’t have the resources of other schools yet … but we are eager to prove we can keep up with everyone else. That we belong.”

Study: Two-thirds of Glaciers on Track to Disappear by 2100 

The world’s glaciers are shrinking and disappearing faster than scientists thought, with two-thirds of them projected to melt out of existence by the end of the century at current climate change trends, according to a new study.

But if the world can limit future warming to just a few more tenths of a degree and fulfill international goals — technically possible but unlikely according to many scientists — then slightly less than half the globe’s glaciers will disappear, said the same study. Mostly small but well-known glaciers are marching to extinction, study authors said.

In an also unlikely worst-case scenario of several degrees of warming, 83% of the world’s glaciers would likely disappear by the year 2100, study authors said.

Thursday’s study in the journal Science examined all of the globe’s 215,000 land-based glaciers — not counting those on ice sheets in Greenland and Antarctica — in a more comprehensive way than past studies. Scientists then used computer simulations to calculate, using different levels of warming, how many glaciers would disappear, how many trillions of tons of ice would melt, and how much it would contribute to sea level rise.

The world is now on track for a 2.7-degree Celsius (4.9 degrees Fahrenheit) temperature rise since pre-industrial times, which by the year 2100 means losing 32% of the world’s glacier mass, or 48.5 trillion metric tons of ice as well as 68% of the glaciers disappearing. That would increase sea level rise by 115 millimeters (4.5 inches) in addition to seas already getting larger from melting ice sheets and warmer water, said study lead author David Rounce.

“No matter what, we’re going to lose a lot of the glaciers,” Rounce, a glaciologist and engineering professor at Carnegie Mellon University, said. “But we have the ability to make a difference by limiting how many glaciers we lose.”

“For many small glaciers it is too late,” said study co-author Regine Hock, a glaciologist at the University of Alaska Fairbanks and the University of Oslo in Norway. “However, globally our results clearly show that every degree of global temperature matters to keep as much ice as possible locked up in the glaciers.”

Projected ice loss by 2100 ranges from 38.7 trillion metric tons to 64.4 trillion tons, depending on how much the globe warms and how much coal, oil and gas is burned, according to the study.

The study calculates that all that melting ice will add anywhere from 90 millimeters (3.5 inches) in the best case to 166 millimeters (6.5 inches) in the worst case to the world’s sea level, 4% to 14% more than previous projections.

That average sea level rise from glaciers would mean more than 10 million people around the world — and more than 100,000 people in the United States — would be living below the high tide line, who otherwise would be above it, said sea level rise researcher Ben Strauss, CEO of Climate Central. Twentieth-century sea level rise from climate change added about 100 millimeters to the surge from 2012 Superstorm Sandy, costing about $8 billion in damage just in itself, he said.

Scientists say future sea level rise will be driven more by melting ice sheets than glaciers.

But the loss of glaciers is about more than rising seas. It means shrinking water supplies for a big chunk of the world’s population, more risk from flood events from melting glaciers and losing historic ice-covered spots from Alaska to the Alps to even near Mount Everest’s base camp, several scientists told The Associated Press.

“For places like the Alps or Iceland … glaciers are part of what makes these landscapes so special,” said National Snow and Ice Data Center Director Mark Serreze, who wasn’t part of the study but praised it. “As they lose their ice in a sense they also lose their soul.”

Hock pointed to Vernagtferner glacier in the Austrian Alps, which is one of the best-studied glaciers in the world, and said “the glacier will be gone.”

The Columbia Glacier in Alaska had 216 billion tons of ice in 2015, but with just a few more tenths of a degree of warming, Rounce calculated it will be half that size. If there’s 4 degrees Celsius (7.2 degrees Fahrenheit) of warming since pre-industrial times, an unlikely worst-case scenario, it will lose two-thirds of its mass, he said.

“It’s definitely a hard one to look at and not drop your jaw at,” Rounce said.

Glaciers are crucial to people’s lives in much of the world, said National Snow and Ice Center Deputy Lead Scientist Twila Moon, who wasn’t part of the study.

“Glaciers provide drinking water, agricultural water, hydropower, and other services that support billions (yes, billions!) of people,” Moon said in an email.

Moon said the study “represents significant advances in projecting how the world’s glaciers may change over the next 80 years due to human-created climate change.”

That’s because the study includes factors in glacier changes that previous studies didn’t and is more detailed, said Ruth Mottram and Martin Stendel, climate scientists at the Danish Meteorological Institute who weren’t part of the research.

This new study better factors in how the glaciers’ ice melts not just from warmer air, but also from water both below and at the edges of glaciers and how debris can slow melt, Stendel and Mottram said. Previous studies concentrated on large glaciers and made regional estimates instead of calculations for each individual glacier.

In most cases, the estimated loss figures Rounce’s team came up with are slightly more dire than earlier estimates.

If the world can somehow limit warming to the global goal of 1.5 degrees Celsius (2.7 degrees Fahrenheit) of warming since pre-industrial times — the world is already at 1.1 degrees (2 degrees Fahrenheit) — Earth will likely lose 26% of total glacial mass by the end of the century, which is 38.7 trillion metric tons of ice melting. Previous best estimates had that level of warming melting translating to only 18% of total mass loss.

“I have worked on glaciers in the Alps and Norway which are really rapidly disappearing,” Mottram said in an email. “It’s kind of devastating to see.”

NFL Player Damar Hamlin Showing ‘Remarkable Improvement’

Buffalo Bills safety Damar Hamlin has shown what physicians treating him are calling “remarkable improvement over the past 24 hours,” the team announced Thursday, three days after the player went into cardiac arrest and had to be resuscitated on the field. 

“While still critically ill, he has demonstrated that he appears to be neurologically intact,” the Bills said in a statement. “His lungs continue to heal and he is making steady progress.” 

Bills rookie cornerback Kaiir Elam also posted a message on his Twitter account that said Hamlin “is doing better, awake and showing signs of improvement.” 

The developments came as the Bills were scheduled to return to practice on Thursday for the first time since Hamlin collapsed after his heart stopped after making a tackle and was rushed to the University of Cincinnati Medical Center during the first quarter of Buffalo’s game against the Bengals on Monday night.

The second-year player has spent the past two days sedated and listed in critical condition.

The Bills’ announcement comes as they prepare to play a home game against the New England Patriots on Sunday, and with the team still dealing with the shock of seeing their teammate collapse on the field, his heart not beating.

After returning home early Tuesday once the game was suspended, the Bills held meetings and a walkthrough practice without any media availability on Wednesday. On Thursday, players were spotted arriving at the facility, though the team has not yet released a practice schedule.

The chilling sight of Hamlin collapsing, which was broadcast to a North American TV audience on ESPN’s “Monday Night Football,” has led to an outpouring of support from fans and players from across the league.

Numerous players — former teammates and those who didn’t know Hamlin until Monday — voiced their support, while saying they were shaken by what happened.

Colts safety Rodney Thomas made the two-hour drive from Indianapolis to Cincinnati on Tuesday just to be by the side of his former high school teammate.

“He’s a fighter. I know he’s a fighter and there’s no other thought in my mind other than him walking out under his own power,” Thomas said Wednesday.

Minnesota Vikings defensive tackle Harrison Phillips, who spent the previous four seasons playing for Buffalo, had dinner delivered to the hospital for Hamlin’s family and medical staff.

Hamlin’s marketing representative Jordon Rooney said Wednesday that the player’s family was buoyed by the words and acts of kindness.

“They are elated right now,” Rooney said. “Damar is still their first concern. But for them, they always look at how they can turn a somewhat troubling situation into a good one. The bounce back from this, for him and his family, is going to be incredible.”

What remains unclear is whether the NFL will reschedule the Bills’ game against the Bengals, which has major implications in determining the top spot in the AFC. The playoffs are set to open on January 14.

The Chiefs (13-3) have a half-game lead over Buffalo (12-3), with the Bills owning the tiebreaker after beating Kansas City this season. The Bengals (11-4) are currently the third seed and have also defeated the Chiefs.

Hamlin was hurt in the first quarter when he was struck squarely in the chest while making what appeared to be routine tackle of Bengals receiver Tee Higgins. Hamlin briefly got up and adjusted his facemask before collapsing backward.

Hamlin was selected by Buffalo in the sixth round of the 2021 draft out of Pitt. He spent his rookie season limited to special teams roles, and took over the starting safety job in Week 3 in place of veteran Micah Hyde, who remains sidelined by a neck injury.

Fans, team owners and players — including Tom Brady and Russell Wilson — have made donations to Hamlin’s Chasing M’s Foundation, which had raised more than $7 million by Thursday morning. 

 

Amazon CEO Says Layoff to Exceed 18,000 Jobs

Amazon.com layoffs will now stretch to more than 18,000 jobs as part of a workforce reduction it previously disclosed, Chief Executive Andy Jassy said in a public staff note on Wednesday.

The layoff decisions, which Amazon will communicate starting January 18, will largely impact the company’s e-commerce and human-resources organizations, he said.

The cuts amount to 6% of Amazon’s roughly 300,000-person corporate workforce and represent a swift turn for a retailer that recently doubled its base pay ceiling to compete more aggressively for talent.

Jassy said in the note that annual planning “has been more difficult given the uncertain economy and that we’ve hired rapidly over the last several years.”

Amazon has more than 1.5 million workers including warehouse staff, making it America’s second-largest private employer after Walmart. It has braced for likely slower growth as soaring inflation encouraged businesses and consumers to cut back spending and its share price has halved in the past year.

Amazon began letting staff go in November from its devices division, with a source telling Reuters at the time it was targeting 10,000 job cuts.

In number, its layoffs now surpass the 11,000 job cuts at Facebook-parent Meta Platforms as well as reductions at other tech-industry peers.

FDA Allows Broader Access to Abortion Pills

In a move that amplifies the debate over access to abortion in the United States, the Food and Drug Administration this week ruled that a drug used in the majority of abortions in the country can be dispensed by retail pharmacies to individuals with valid prescriptions.

Until the ruling, that drug, mifepristone, could be dispensed only by certified clinics and doctors’ offices, or by specific online pharmacies. Now, retail pharmacies, including those of major chains like CVS and Walgreens, will have the ability, though not the obligation, to carry the medication.

However, it will remain illegal for pharmacies to dispense the medication in at least 12 states, which have passed laws banning abortions.

Mifepristone blocks hormones that contribute to the development of a fetus. When a dose is followed one to two days later with a dose of a second drug, misoprostol, which induces muscle contractions, the result is an abortion. Known as a medical abortion, the two-pill regimen accounts for more than half of all abortions in the U.S. Both mifepristone and misoprostol have other uses unrelated to abortion.

The ruling came days after it was announced that the Justice Department had issued a finding, at the request of the U.S. Postal Service, that it is legal to use the U.S. mail to deliver mifepristone and misoprostol. That finding would apply regardless of the laws of individual states.

 

State laws differ 

The Supreme Court’s ruling last year that abolished the federal right to an abortion, which was put in place by the 1973 court decision Roe v. Wade, left it to individual states to craft abortion laws themselves. This has led to a patchwork of abortion regulation across the country.

Sixteen states have adopted laws that ban all or practically all abortions. In those states, as well as in several others, laws restricting abortions would also make it illegal to sell mifepristone and misoprostol within their borders, regardless of the FDA’s position.

Other states have explicitly protected the right to abortion in their laws, with several amending their constitutions to do so.

If retail pharmacies opted to sell abortion drugs in states where they are legal, it would further widen the already large gap in abortion access in some parts of the country. In certain regions, particularly states in the Deep South, a woman seeking access to an abortion has to travel hundreds of miles to reach a state that has not banned the procedure.

Abortion rights activists cheered 

Supporters of the right to an abortion said that they were encouraged by the FDA’s ruling.

“Today’s news is a step in the right direction for health equity. Being able to access your prescribed medication abortion through the mail or to pick it up in person from a pharmacy like any other prescription is a game-changer for people trying to access basic health care,” Alexis McGill Johnson, president and CEO of Planned Parenthood Federation of America, said in a statement.

However, advocates also noted that the sale of the pills would remain illegal in 12 states, because of abortion bans passed by state legislatures.

“Today’s announcement means that people in states where abortion is legal will be able to consult with their health care providers and obtain medication abortion in the way that works best for them — whether it’s through their neighborhood pharmacy or through the mail,” Nancy Northup, president and CEO of the Center for Reproductive Rights, said in a statement. “However, 12 states have banned abortion, and this move will not change anything for the people in those states, which is why Congress must pass the Women’s Health Protection Act to ensure the right to access abortion care is protected nationwide.”

Abortion-rights opponents unhappy

Groups that support the restriction or outright elimination of abortion in the U.S. were unhappy with the ruling, with some criticizing the administration of President Joe Biden over its support for abortion rights.

Although the medical establishment, including the FDA, has said that medical abortions are safe, anti-abortion-rights groups point to rare side effects, including heavy bleeding and infection, as proof that they are dangerous.

“Today’s announcement is yet another in a long train of actions the Biden administration has taken that put women at grave risk, in its headlong rush to push abortion drugs on the American public,” Steven H. Aden, chief legal officer and general counsel for Americans United for Life, said in a statement emailed to VOA.

“The Biden administration has once again proved that it values abortion industry profits over women’s safety and unborn children’s lives,” Marjorie Dannenfelser, president of Susan B. Anthony Pro-Life America, said in a statement.

Retail pharmacies consider options 

It was not clear whether retail pharmacies, including those of large chains, would carry mifepristone and misoprostol in states that have not made abortion illegal. To do so, they would have to comply with special rules put forward by the FDA.

They would also have to assess the reputational costs and benefits of a decision that will likely have repercussions that extend beyond the balance sheet.

“We’re reviewing the FDA’s updated Risk Evaluation and Mitigation Strategy (REMS) drug safety program for mifepristone to determine the requirements to dispense in states that do not restrict the dispensing of medications prescribed for elective termination of pregnancy,” Amy Thibault, lead director of external communications for CVS Pharmacy, told VOA.

Fraser Engerman, a senior director for external relations with Walgreen Co., told VOA, “We look forward to reviewing the FDA’s announcement and mifepristone REMS program, and we will continue to enable our pharmacists to dispense medications consistent with federal and state law.”

Iran Releases Oscar-Winning Film Actress Held Over Protests

Iran released a prominent actress from an Oscar-winning film on Wednesday, nearly three weeks after she was jailed for criticizing a crackdown on anti-government protests, local reports said.

Iran’s semi-official ISNA news agency said Taraneh Alidoosti, the 38-year-old star of Asghar Farhadi’s Oscar-winning “The Salesman,” was released on bail. Her mother, Nadere Hakimelahi, had earlier said she would be released in a post on Instagram.

After her release from the notorious Evin Prison in Tehran on Wednesday, Alidoosti posed with flowers among her friends. No further details have been released about her case.

Alidoosti was among several Iranian celebrities to express support for the nationwide protests and criticize the authorities’ violent clampdown on dissent. She had posted at least three messages in support of the protests on Instagram before her account was disabled.

One message had expressed solidarity with the first man to be executed on charges linked to the protests, which were triggered by the death of a woman in police custody and have escalated into widespread calls for the overthrow of Iran’s ruling clerics.

The protests mark one of the biggest challenges to the Islamic Republic since it was established after the 1979 revolution. Security forces have used live ammunition, bird shot, tear gas and batons to disperse protesters, according to rights groups.

Mohsen Shekari was executed Dec. 9 after being charged by an Iranian court with blocking a street in Tehran and attacking a member of the country’s security forces with a machete. A week later, Iran executed a second prisoner, Majidreza Rahnavard, by public hanging. He had been accused of stabbing two members of the paramilitary Basij militia, which is leading the crackdown.

Activists say at least a dozen people have been sentenced to death in closed-door hearings over charges linked to the protests.

“His name was Mohsen Shekari,” Alidoosti wrote on an account with some 8 million followers before her arrest. “Every international organization who is watching this bloodshed and not taking action, is a disgrace to humanity.”

At least 516 protesters have been killed and over 19,000 people have been arrested, according to Human Rights Activists in Iran, a group that has closely monitored the unrest. Iranian authorities have not provided an official count of those killed or detained.

Hengameh Ghaziani and Katayoun Riahi, two other famous Iranian actresses, were arrested in November for expressing solidarity with protesters on social media. Voria Ghafouri, an Iranian soccer star, was also arrested that month for ”insulting the national soccer team and propagandizing against the government.” All three have been released.

The protests began in mid-September, when 22-year-old Mahsa Amini died after being arrested by Iran’s morality police for allegedly violating the Islamic Republic’s strict dress code. Women have played a leading role in the protests, with many publicly stripping off the compulsory Islamic headscarf, known as the hijab.

The protesters say they are fed up after decades of political and social repression. One of the main slogans has been “Death to the dictator,” referring to Iran’s 83-year-old Supreme Leader Ayatollah Ali Khamenei, who has held the country’s highest office for more than three decades.

Iranian officials blame the protests on the U.S. and other foreign powers. State-linked media have highlighted attacks on security forces, while authorities have imposed heavy restrictions on coverage of the demonstrations, including periodically cutting off internet access.

Khamenei, who has said little about the protests, spoke about Islamic dress on Wednesday in a meeting with women, saying the hijab is necessary but that those who do not “completely observe” the practice “should not be accused of being non-religious or against the revolution.”

Even before the protests, many Iranian women wore the headscarf loosely, and authorities sometimes eased off on enforcing it, particularly during the presidency of Hassan Rouhani, a relative moderate who governed from 2013 to 2021. His successor, the hard-liner Ebrahim Raisi, had moved to tighten the restrictions.

Alidoosti had previously criticized the Iranian government and its police force before this year’s protests.

In June 2020, she was given a suspended five-month prison sentence after she criticized the police on Twitter in 2018 for assaulting a woman who had removed her headscarf.

Other well-known movies Alidoosti has starred in include “The Beautiful City” and “About Elly.”

Meta Fined 390 Million Euros in Latest European Privacy Crackdown

European Union regulators on Wednesday hit Facebook parent Meta with hundreds of millions in fines for privacy violations and banned the company from forcing users in the 27-nation bloc to agree to personalized ads based on their online activity. 

Ireland’s Data Protection Commission imposed two fines totaling 390 million euros ($414 million) in its decision in two cases that could shake up Meta’s business model of targeting users with ads based on what they do online. The company says it will appeal. 

A decision in a third case involving Meta’s WhatsApp messaging service is expected later this month. 

Meta and other Big Tech companies have come under pressure from the European Union’s privacy rules, which are some of the world’s strictest. Irish regulators have already slapped Meta with four other fines for data privacy infringements since 2021 that total more than 900 million euros and have a slew of other open cases against a number of Silicon Valley companies. 

Meta also faces regulatory headaches from EU antitrust officials in Brussels flexing their muscles against tech giants: They accused the company last month of distorting competition in classified ads. 

The Irish watchdog — Meta’s lead European data privacy regulator because its regional headquarters is in Dublin — fined the company 210 million euros for violations of EU data privacy rules involving Facebook and an additional 180 million euros for breaches involving Instagram. 

The decision stems from complaints filed in May 2018 when the 27-nation bloc’s privacy rules, known as the General Data Protection Regulation, or GDPR, took effect. 

Previously, Meta relied on getting informed consent from users to process their personal data to serve them with personalized, or behavioral, ads, which are based on what users search for online, the websites they visit or the videos they click on. 

When GDPR came into force, the company changed the legal basis under which it processes user data by adding a clause to the terms of service for advertisements, effectively forcing users to agree that their data could be used. That violates EU privacy rules. 

The Irish watchdog initially sided with Meta but changed its position after its draft decision was sent to a board of EU data protection regulators, many of whom objected. 

In its final decision, the Irish watchdog said Meta “is not entitled to rely on the ‘contract’ legal basis” to deliver behavioral ads on Facebook and Instagram. 

Meta said in a statement that “we strongly believe our approach respects GDPR, and we’re therefore disappointed by these decisions and intend to appeal both the substance of the rulings and the fines.” 

Meta has three months to ensure its “processing operations” comply with the EU rules, though the ruling doesn’t specify what the company has to do. Meta noted that the decision doesn’t prevent it from displaying personalized ads, it only covers the legal basis for handling user data. 

Max Schrems, the Austrian lawyer and privacy activist who filed the complaints, said the ruling could deal a big blow to the company’s profits in the EU, because “people now need to be asked if they want their data to be used for ads or not” and can change their mind at any time. 

“The decision also ensures a level playing field with other advertisers that also need to get opt-in consent,” he said. 

Making changes to comply with the decision could add to costs for a company already facing rising business challenges. Meta reported two straight quarters of declining revenue as advertising sales dropped because of competition from TikTok, and it laid off 11,000 workers amid broader tech industry woes.